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Results for "

myostatin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) DNA/RNA Synthesis (1) Dystrophin (2) IGF-1R (1) mTOR (1) PI3K (1) TGF-beta/Smad (8) TGF-β Receptor (1) YAP (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (2)
Oligonucleotides:	Antisense Oligonucleotides (2)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P10476

Myostatin inhibitory peptide 2	TGF-beta/Smad	Others
Myostatin inhibitory peptide 2 (compd 2) is a *myostatin* inhibitor with a K_d of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders .

HY-P10242

Myostatin inhibitory peptide 7	TGF-beta/Smad	Others
Myostatin inhibitory peptide 7 is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 inhibits *myostatin* with a K_d of 29.7 nM. Myostatin inhibitory peptide 7 can be used for researches of muscle atrophic disorders .

HY-P99857

Domagrozumab PF-06252616	TGF-beta/Smad	Metabolic Disease
Domagrozumab is an anti-myostatin humanized monoclonal antibody with a K_D value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD) .

HY-P99370

Landogrozumab 1 Publications Verification LY2495655; Anti-GDF8 / myostatin Reference Antibody (landogrozumab)	TGF-beta/Smad	Inflammation/Immunology Cancer
Landogrozumab (LY2495655) is an humanized *anti-myostatin* monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .

HY-P99588

Stamulumab 1 Publications Verification MYO-029	TGF-β Receptor	Metabolic Disease
Stamulumab (MYO-029) is a recombinant human IgG1λ antibody that binds to *myostatin* and neutralizes its activity by preventing binding to its endogenous high-affinity receptor ActRIIB. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia in SCID mice. Stamulumab has the potential for Becker muscular dystrophy (BMD), facioscapulohumeral dystrophy (FSHD), and limb-girdle muscular dystrophy (LGMD) research .

HY-P99388

Trevogrumab REGN-1033	TGF-beta/Smad	Metabolic Disease
Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .

HY-P99518

Taldefgrobep alfa BMS 986089; RG 6206; RO 7239361; BHV2000	TGF-beta/Smad	Others
Taldefgrobep alfa (BMS 986089; RG 6206; RO 7239361) is a potent inhibitory antibody targeting to human *myostatin*. Taldefgrobep alfa is a fusion protein composed of a human IgG1-Fc domain and Adnectin domain. Taldefgrobep alfa can be used for spinal muscular atrophy (SMA) research .

HY-P10242A

Myostatin inhibitory peptide 7 TFA	TGF-beta/Smad	Others
Myostatin inhibitory peptide 7 TFA is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 TFA inhibits *myostatin* with a K_d of 29.7 nM. Myostatin inhibitory peptide 7 TFA can be used for researches of muscle atrophic disorders .

HY-P10476A

Myostatin inhibitory peptide 2 TFA	TGF-beta/Smad	Others
Myostatin inhibitory peptide 2 (compd 2) TFA is a *myostatin* inhibitor with a K_d of 35.9 nM. Myostatin inhibitory peptide 2 TFA can be used for researches of muscle atrophic disorders .

HY-130687A

Psicose DL-Psicose	PI3K mTOR Akt IGF-1R	Inflammation/Immunology
Psicose is a natural and low-calorie sweetener. Psicose can activate the PI3K/Akt/mTOR pathway to promote muscle synthesis. Psicose can upregulate IGF-1 and downregulate Myostatin. Psicose regulates mitochondrial function by increasing G6P activity. Psicose enhances antioxidant enzyme activity and reduces oxidative stress markers. Psicose reduces plasma triglycerides and total cholesterol. Psicose can improve muscle fiber size and reduce fibrosis. Psicose can be used for research on sarcopenia .

HY-132611

Golodirsen SRP-4053	Dystrophin	Neurological Disease
Golodirsen (SRP-4053) is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen can restore the expression of the anti-myostatin protein. Golodirsen can be used for the research of duchenne muscular dystrophy (DMD) .

HY-132611A

Golodirsen sodium SRP-4053 sodium	DNA/RNA Synthesis Dystrophin	Neurological Disease
Golodirsen (SRP-4053) sodium is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen sodium restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen sodium can restore the expression of the anti-myostatin protein. Golodirsen sodium can be used for the research of duchenne muscular dystrophy (DMD) .

HY-112821

IBS008738 1 Publications Verification	YAP	Inflammation/Immunology
IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model .

Cat. No.	Product Name	Target	Research Area

HY-P10476

Myostatin inhibitory peptide 2	TGF-beta/Smad	Others
Myostatin inhibitory peptide 2 (compd 2) is a *myostatin* inhibitor with a K_d of 35.9 nM. Myostatin inhibitory peptide 2 can be used for researches of muscle atrophic disorders .

HY-P10242

Myostatin inhibitory peptide 7	TGF-beta/Smad	Others
Myostatin inhibitory peptide 7 is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 inhibits *myostatin* with a K_d of 29.7 nM. Myostatin inhibitory peptide 7 can be used for researches of muscle atrophic disorders .

HY-P10242A

Myostatin inhibitory peptide 7 TFA	TGF-beta/Smad	Others
Myostatin inhibitory peptide 7 TFA is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain. Myostatin inhibitory peptide 7 TFA inhibits *myostatin* with a K_d of 29.7 nM. Myostatin inhibitory peptide 7 TFA can be used for researches of muscle atrophic disorders .

HY-P10476A

Myostatin inhibitory peptide 2 TFA	TGF-beta/Smad	Others
Myostatin inhibitory peptide 2 (compd 2) TFA is a *myostatin* inhibitor with a K_d of 35.9 nM. Myostatin inhibitory peptide 2 TFA can be used for researches of muscle atrophic disorders .

Cat. No.	Product Name	Target	Research Area

HY-P99857

Domagrozumab PF-06252616	TGF-beta/Smad	Metabolic Disease
Domagrozumab is an anti-myostatin humanized monoclonal antibody with a K_D value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD) .

HY-P99370

Landogrozumab 1 Publications Verification LY2495655; Anti-GDF8 / myostatin Reference Antibody (landogrozumab)	TGF-beta/Smad	Inflammation/Immunology Cancer
Landogrozumab (LY2495655) is an humanized *anti-myostatin* monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .

HY-P99588

Stamulumab 1 Publications Verification MYO-029	TGF-β Receptor	Metabolic Disease
Stamulumab (MYO-029) is a recombinant human IgG1λ antibody that binds to *myostatin* and neutralizes its activity by preventing binding to its endogenous high-affinity receptor ActRIIB. Stamulumab leads to muscle fiber hypertrophy and not hyperplasia in SCID mice. Stamulumab has the potential for Becker muscular dystrophy (BMD), facioscapulohumeral dystrophy (FSHD), and limb-girdle muscular dystrophy (LGMD) research .

HY-P99388

Trevogrumab REGN-1033	TGF-beta/Smad	Metabolic Disease
Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .

HY-P99518

Taldefgrobep alfa BMS 986089; RG 6206; RO 7239361; BHV2000	TGF-beta/Smad	Others
Taldefgrobep alfa (BMS 986089; RG 6206; RO 7239361) is a potent inhibitory antibody targeting to human *myostatin*. Taldefgrobep alfa is a fusion protein composed of a human IgG1-Fc domain and Adnectin domain. Taldefgrobep alfa can be used for spinal muscular atrophy (SMA) research .

Species:	Human (8) Rat (5) Mouse (5) Cat (1)
Tag:	His (5) Tag Free (3) Avi (2)
Source:	HEK293 (7) CHO (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P72632

	GDF-8 Protein, Human/Mouse/Rat (HEK293) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Rat;Human;Mouse	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (HEK293) is the recombinant rat-derived GDF-8 protein, expressed by HEK293 , with tag free.

HY-P704015

	Latent GDF-8 Protein, Human (HEK293, His) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Human	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. Latent GDF-8 Protein, Human (HEK293, His) is the recombinant human-derived Latent GDF-8 protein, expressed by HEK293, with N-His labeled tag.

HY-P702874

	GDF-8 Protein, Human/Mouse/Rat (109a.a, HEK293) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Mouse;Human;Rat	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (109a.a, HEK293) is the recombinant rat-derived GDF-8 protein, expressed by HEK293 , with tag free.

HY-P700498

	MSTN Protein, Cat (HEK293, His) myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8	Cat	HEK293
	MSTN (Myostatin) serves as a dedicated negative regulator of skeletal muscle growth, forming homodimers through disulfide linkages. It inhibits WFIKKN2 activity through interaction and further contributes to its role in negatively modulating skeletal muscle growth by engaging with FSTL3. MSTN Protein, Cat (HEK293, His) is the recombinant cat-derived MSTN protein, expressed by HEK293 , with N-10*His labeled tag.

HY-P702874Y

	GDF-8 Protein, Human/Mouse/Rat (Biotinylated, 109a.a, HEK293, Avi, Solution) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Rat;Mouse;Human	HEK293
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human/Mouse/Rat (Biotinylated, 109a.a, HEK293, Avi, Solution) is the recombinant rat/mouse/human-derived GDF-8 protein, expressed by HEK293, with C-Avi labeled tag.

HY-P704631

	GDF-8 Protein, Human (CHO) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Human	CHO
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human (CHO) is the recombinant human-derived GDF-8 protein, expressed by CHO, with tag free.

HY-P704630

	GDF-8 Protein, Human (CHO, His) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Rat;Mouse;Human	CHO
	GDF-8 (Growth Differentiation Factor 8) functions as a specific negative regulator of skeletal muscle growth. It forms homodimers linked by disulfide bonds and inhibits WFIKKN2 activity through interaction. GDF-8 also interacts with FST3, playing a regulatory role in skeletal muscle growth modulation. GDF-8 Protein, Human (CHO, His) is the recombinant rat/mouse/human-derived GDF-8 protein, expressed by CHO, with N-His labeled tag.

HY-P705231

	GDF-8 Protein, Human/Mouse/Rat (Biotinylated, HEK293, His) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Rat;Mouse;Human	HEK293

HY-P705393

	Latent GDF-8 Protein, Human (Biotinylated, HEK293, His-Avi) Growth/differentiation factor 8; GDF-8; myostatin; MSTN	Human	HEK293

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HY-P85185

	GDF-8 Antibody (YA4877) MSTN; GDF8; Growth/differentiation factor 8; GDF-8; myostatin	WB, ELISA	Human
	GDF-8 Antibody (YA4877) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GDF-8.

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Cat. No.	Product Name		Classification

HY-132611

Golodirsen SRP-4053		Antisense Oligonucleotides
Golodirsen (SRP-4053) is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen can restore the expression of the anti-myostatin protein. Golodirsen can be used for the research of duchenne muscular dystrophy (DMD) .

HY-132611A

Golodirsen sodium SRP-4053 sodium		Antisense Oligonucleotides
Golodirsen (SRP-4053) sodium is an antisense oligonucleotide of the phophorodiamidate morpholino oligomer (PMO). Golodirsen sodium restores the reading frame of the Duchenne muscular dystrophy (DMD) gene by modifying the splicing process of the pre-mRNA, skipping exon 53. Golodirsen sodium can restore the expression of the anti-myostatin protein. Golodirsen sodium can be used for the research of duchenne muscular dystrophy (DMD) .

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