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Results for "

modification sites

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Screening Libraries

2

Fluorescent Dye

5

Biochemical Assay Reagents

1

Peptides

2

Natural
Products

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119390
    AA-CW236

    		DNA Methyltransferase Cancer
    AA-CW236 is a MGMT (O6-methylguanine DNA methyltransferase) inhibitor. AA-CW236 targets MGMT active site Cys145 for covalent modification .
    AA-CW236
  • HY-136276
    DMNB-caged-Serine

    		Amino Acid Derivatives Others
    DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation .
    DMNB-caged-Serine
  • HY-D2911
    Pantetheine probe PP-3

    		Biochemical Assay Reagents Metabolic Disease
    Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
    Pantetheine probe PP-3
  • HY-134389
    6-Phe-cAMP

    N6-Phenyladenosine-3',5'-cyclic monophosphate

    		 PKA Cancer
    6-Phe-cAMP is a site-selective and highly membrane-permeant activator of protein kinase A (PKA), with a strong preference for site A of both isozymes. 6-Phe-cAMP can undergo phosphorothioate modification .
    6-Phe-cAMP
  • HY-W1048851A
    4-Arm PEG-MAL (MW 5000)

    		Biochemical Assay Reagents Others
    4-Arm PEG-MAL (MW 5000) can be used for site-specific protein and peptide modification and can be used for drug delivery .
    4-Arm PEG-MAL (MW 5000)
  • HY-W1048851D
    4-Arm PEG-MAL (MW 40000)

    		Biochemical Assay Reagents Others
    4-Arm PEG-MAL (MW 40000) can be used for site-specific protein and peptide modification and can be used for drug delivery .
    4-Arm PEG-MAL (MW 40000)
  • HY-W1048851B
    4-Arm PEG-MAL (MW 10000)

    		Biochemical Assay Reagents Others
    4-Arm PEG-MAL (MW 10000) can be used for site-specific protein and peptide modification and can be used for drug delivery .
    4-Arm PEG-MAL (MW 10000)
  • HY-W1048851C
    4-Arm PEG-MAL (MW 20000)

    		Biochemical Assay Reagents Others
    4-Arm PEG-MAL (MW 205000) can be used for site-specific protein and peptide modification and can be used for drug delivery .
    4-Arm PEG-MAL (MW 20000)
  • HY-157140
    HibK

    		Others Others
    HibK is is a new type of histone mark that is widely distributed in histone proteins. HibK as a useful tool can be used for probing post-translational modification by site-specifically incorporate HibK into proteins .
    HibK
  • HY-Z15868
    5-Hydroxycytidine

    		Nucleoside Antimetabolite/Analog Infection
    5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli .
    5-Hydroxycytidine
  • HY-137028
    2′-Thioadenosine

    PD157432

    		 EGFR Cancer
    2'-Thioadenosine (PD157432) is a selective and irreversible inhibitor of ErbB-1 and ErbB-2, with an IC50 of 45 µM for ErbB-2. 2'-Thioadenosine covalently inactivates ErbB-1 via modification of a cysteine residue at the active site .
    2′-Thioadenosine
  • HY-D1363
    BDP R6G maleimide

    		Fluorescent Dye Others
    BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
    BDP R6G maleimide
  • HY-157006A
    TCO-PEG3-NH2

    		Biochemical Assay Reagents Others
    TCO-PEG3-NH2 is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. The amino group of TCO-PEG3-NH2 can react with compounds containing carboxyl, ester, or other reactive groups to form stable amide bonds, enabling site-specific conjugation or modification of biomolecules.
    TCO-PEG3-NH2
  • HY-P5506
    C5a Receptor agonist, W5Cha

    		Complement System Others
    C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor .
    C5a Receptor agonist, W5Cha
  • HY-113138
    3-Methyluridine
    1 Publications Verification

    N3-Methyluridine

    		 Endogenous Metabolite Metabolic Disease
    3-Methyluridine (m 3U; N3-Methyluridine) is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function. For example, it affects ribosomal subunit binding and tRNA interaction. 3-Methyluridine is often used as a key raw material for the synthesis of modified nucleotides, and is used to construct RNA oligonucleotides containing methylation modifications to study the effects of RNA methylation on gene expression and drug resistance .
    3-Methyluridine
  • HY-113138R
    3-Methyluridine (Standard)

    		Endogenous Metabolite Metabolic Disease
    3-Methyluridine (Standard) is the analytical standard of 3-Methyluridine. This product is intended for research and analytical applications. 3-Methyluridine (m3U; N3-Methyluridine) is a methylated nucleotide present in ribosomal RNA (rRNA), mainly targeting specific base sites of RNA molecules such as 23S rRNA. 3-Methyluridine can introduce a methyl group at the N3 position of uracil, affecting the secondary structure stability and base pairing ability of RNA, and regulating ribosome function. For example, it affects ribosomal subunit binding and tRNA interaction. 3-Methyluridine is often used as a key raw material for the synthesis of modified nucleotides, and is used to construct RNA oligonucleotides containing methylation modifications to study the effects of RNA methylation on gene expression and drug resistance .
    3-Methyluridine (Standard)
  • HY-131455A
    Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA

    		Biochemical Assay Reagents Others
    Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA is used for detection of modification site for N-myristoylated and GPI-anchored proteins in blood-stage P. falciparum . Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 (TFA) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 TFA

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