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Results for "

membrane-permeant

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

2

Fluorescent Dye

4

Peptides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153056
    BNN3

    		NO Synthase Others
    BNN3 is a caged nitric oxide (NO) donor. BNN3 is membrane-permeant and incorporated in the lipid membrane .
    BNN3
  • HY-P1369
    DynaMin inhibitory peptide, myristoylated

    		Dynamin Neurological Disease
    DynaMin inhibitory peptide, myristoylated is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated is a membrane-permeant form of the peptide that prevents endocytosis .
    DynaMin inhibitory peptide, myristoylated
  • HY-103316A
    Ned 19
    2 Publications Verification

    		 Calcium Channel Cardiovascular Disease Cancer
    Ned 19 is a selective membrane-permeant non competitive NAADP antagonist and inhibits NAADP-mediated Ca 2+ signaling, with an IC50 of 65 nM . Ned 19 strongly inhibits tumor growth and vascularization as well as lung metastases in mice .
    Ned 19
  • HY-141510
    myo-Inositol trispyrophosphate hexasodium

    ITPP hexasodium

    		 HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease Cancer
    myo-Inositol trispyrophosphate (ITPP) hexasodium is a salt form of inositol triphosphate (ITPP). myo-Inositol trispyrophosphate (ITPP) hexasodium is a membrane-permeant hemoglobin allosteric regulator. myo-Inositol trispyrophosphate (ITPP) hexasodium enhances the oxygen release capacity of red blood cells by reducing the affinity of hemoglobin to oxygen. myo-Inositol trispyrophosphate (ITPP) hexasodium can be used in the study of cardiovascular disease and cancer .
    myo-Inositol trispyrophosphate hexasodium
  • HY-141510A
    myo-Inositol trispyrophosphate hexa-triethylamine

    ITPP hexa-triethylamine

    		 Biochemical Assay Reagents HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease Cancer
    myo-Inositol trispyrophosphate (ITPP) hexa-triethylamine is a salt form of inositol triphosphate (ITPP). myo-Inositol trispyrophosphate hexa-triethylamine is a membrane-permeant hemoglobin allosteric regulator. myo-Inositol trispyrophosphate hexa-triethylamine enhances the oxygen release capacity of red blood cells by reducing the affinity of hemoglobin to oxygen. myo-Inositol trispyrophosphate hexa-triethylamine can be used in the study of cardiovascular disease and cancer .
    myo-Inositol trispyrophosphate hexa-triethylamine
  • HY-134389
    6-Phe-cAMP

    N6-Phenyladenosine-3',5'-cyclic monophosphate

    		 PKA Cancer
    6-Phe-cAMP is a site-selective and highly membrane-permeant activator of protein kinase A (PKA), with a strong preference for site A of both isozymes. 6-Phe-cAMP can undergo phosphorothioate modification .
    6-Phe-cAMP
  • HY-D1643
    5,5'-Dinitro BAPTA AM

    		Biochemical Assay Reagents Others
    5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca 2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand .
    5,5'-Dinitro BAPTA AM
  • HY-D1758
    Fura-5F AM

    		Fluorescent Dye Others
    Fura-5F AM is a membrane-permeant fluorescent calcium indicator. Upon entering the cell, this probe is hydrolyzed by cytosilic esterases and trapped as the active chelator.
    Fura-5F AM
  • HY-P1369A
    DynaMin inhibitory peptide, myristoylated TFA

    		Dynamin Neurological Disease
    DynaMin inhibitory peptide, myristoylated TFA is a DynaMin inhibitor to interfere with the binding of amphiphysin with dynamin. DynaMin inhibitory peptide, myristoylated TFA is a membrane-permeant form of the peptide that prevents endocytosis .
    DynaMin inhibitory peptide, myristoylated TFA
  • HY-134299
    8-CPT-cAMP-AM

    8-(4-Chlorophenylthio)-cAMP-AM

    		 Ras Others
    8-CPT-cAMP-AM is a highly membrane-permeant analogue of signal molecule cAMP. 8-CPT-cAMP-AM is an activator of cAMP- and cGMP-dependent protein kinases and of Epac (exchange protein activated by cAMP) .
    8-CPT-cAMP-AM
  • HY-D1746
    EDTA-AM

    EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester

    		 Biochemical Assay Reagents Mitosis Others
    EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .
    EDTA-AM
  • HY-P2307
    Tat-NR2Baa

    		iGluR NO Synthase Neurological Disease
    Tat-NR2BAA is the control peptide of Tat-NR2B9c (HY-P0117), inactive. The sequence of Tat-NR2BAA is similar to Tat-NR2B9c, but it has a double-point mutation in the COOH terminal tSXV motif, making it incapable of binding PSD-95. Tat-NR2B9c is a membrane-permeant peptide and disrupts PSD-95/NMDAR binding, correlate with uncoupling NR2B- and/or NR2A-type NMDARs from PSD-95 .
    Tat-NR2Baa
  • HY-P2307A
    Tat-NR2Baa TFA

    		iGluR NO Synthase Neurological Disease
    Tat-NR2BAA TFA is the control peptide of Tat-NR2B9c (HY-P0117), inactive. The sequence of Tat-NR2BAA TFA is similar to Tat-NR2B9c, but it has a double-point mutation in the COOH terminal tSXV motif, making it incapable of binding PSD-95. Tat-NR2B9c is a membrane-permeant peptide and disrupts PSD-95/NMDAR binding, correlate with uncoupling NR2B- and/or NR2A-type NMDARs from PSD-95 .
    Tat-NR2Baa TFA

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