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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

mast cell chymase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Angiotensin Receptor (1) Cathepsin (1) MMP (1) Proteasome (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (3)

4

Inhibitors & Agonists

2

Recombinant Proteins

1

Antibodies

Targets Recommended: Microtubule‐associated serine/threonine kinase (MAST) Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor VISTA BCL6 Tim3 BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

GI-129471	MMP	Inflammation/Immunology Cancer
GI-129471 is a MMP inhibitor. GI-129471 exhibits inhibitory activity against cancer cell invasion. GI-129471 can completely block the enhanced production of IgE and IgG1 by mouse B cells induced by rat mast cell protease-I (RMCP-I). GI-129471 can be used for the study of cancer and mast cell chymase-regulated immunological processes .

Chymase-IN-1	Proteasome	Inflammation/Immunology
Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell *chymase* with an IC₅₀ of 29 nM.

Chymase	Angiotensin Receptor	Cardiovascular Disease
Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. Chymase is released into the extracellular stroma in the context of inflammatory signals, tissue injury and cellular stress. Chymase is also involved in angiotensin II (Ang II) production, which is used in cardiovascular disease studies .

JNJ-10311795 RWJ-355871	Cathepsin	Inflammation/Immunology
JNJ-10311795 (RWJ-355871), a potent dual inhibitor of neutrophil cathepsin G (K_i = 38 nM) and mast cell *chymase* (K_i = 2.3 nM), exhibits noteworthy antiinflammatory activity .

Species:	Human (1) Mouse (1)
Tag:	His (2)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	Chymase/CMA1 Protein, Mouse (His) Alpha-chymase; mast cell chymase 1; mast cell protease 5; mMCP-5; mast cell protease I	Mouse	E. coli
	Chymase/CMA1 Protein, a prominent secreted protease in mast cells, is implicated in various physiological processes, including the generation of vasoactive peptides, extracellular matrix degradation, and the regulation of gland secretion.Chymase/CMA1 Protein, Mouse (His) is the recombinant mouse-derived Chymase/CMA1 protein, expressed by E.coli , with N-His labeled tag.

	Chymase/CMA1 Protein, Human (sf9, His) Alpha-chymase; mast cell chymase 1; mast cell protease 5; mMCP-5	Human	Sf9 insect cells
	Chymase/CMA1 Protein, a secreted protease from mast cells, plays a significant role in generating vasoactive peptides, degrading the extracellular matrix, and regulating gland secretion. Chymase/CMA1 Protein, Human (sf9, His) is the recombinant human-derived Chymase/CMA1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

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	Mast Cell Chymase Antibody (YA1629) chymase 1; chymase; CMA1; CYH; CYM; Mcp-5; MCP3P; Mcpt5; MCT1; MMCP-5	WB, IHC-P	Human
	Mast Cell Chymase Antibody (YA1629) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mast Cell Chymase.

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