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Results for "

macrophage-stimulating compound

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101716
    RP-54745
    1 Publications Verification

    		 Interleukin Related Inflammation/Immunology
    RP-54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
    RP-54745
  • HY-136512
    Streptazolin

    		Antibiotic Infection Inflammation/Immunology
    Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling .
    Streptazolin
  • HY-144226
    NLRP3/AIM2-IN-3
    5+ Cited Publications

    		 NOD-like Receptor (NLR) AIM2 Pyroptosis Inflammation/Immunology
    NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. NLRP3/AIM2-IN-3 shows inhibitory efficacy against pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 ± 0.008 μM. NLRP3/AIM2-IN-3 disturbs the interaction of NLRP3 or AIM2 with the adaptor protein ASC and inhibited ASC oligomerization .
    NLRP3/AIM2-IN-3
  • HY-161833
    HSP90-IN-31

    		Interleukin Related TNF Receptor Inflammation/Immunology
    HSP90-IN-31 (compound Be01) causes reduction of CD80 and CD86 expression on dendritic cells (DCs). HSP90-IN-31 decreases the production of pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β) in BMDC and peritoneal macrophages stimulated by LPS (HY-D1056). Under the delayed-type hypersensitivity (DTH) mice model, HSP90-IN-31 reduces ear swelling and pro-inflammatory cytokines in the spleen .
    HSP90-IN-31

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