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Results for "

lipidomic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Endogenous Metabolite (10) Isotope-Labeled Compounds (2)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (8) Neurological Disease (1)
Oligonucleotides:	Phospholipids (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70271

γ-Linolenoyl-CoA 6Z,9Z,12Z-Octadecatrienoyl-coenzyme A; γ-Linolenoylcoenzyme A; 6Z,9Z,12Z-Octadecatrienoyl-CoA	Endogenous Metabolite	Metabolic Disease
γ-Linolenoyl-CoA (C18:3(n6)-CoA) is a fatty acyl-CoA that can be used for lipidomics analysis of fatty acid-coenzyme A (FA-CoA) through LCMS/MS .

HY-W250743

Cresyl diphenyl phosphate	Biochemical Assay Reagents	Others
Cresyl diphenyl phosphate is a compound that disrupts lipid homeostasis in zebrafish embryos, causing alterations in lipid content and lipidomic profiles, as well as affecting gene expression and energy homeostasis. \|

HY-120965

N-Palmitoyl Taurine	Endogenous Metabolite	Metabolic Disease
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered. N-Palmitoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Its function is currently under investigation.

HY-W329357

15:0 Lyso PC 1 Publications Verification	Endogenous Metabolite	Cardiovascular Disease
15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .

HY-120964

N-Stearoyl Taurine	Endogenous Metabolite	Metabolic Disease
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered.2 This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3 N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling.

HY-157620

18:0 Lyso PS sodium	Endogenous Metabolite
18:0 Lyso PS sodium is a bioactive molecule with the activity of promoting cell signaling. 18:0 Lyso PS sodium plays an important role in regulating the fluidity and integrity of cell membranes. 18:0 Lyso PS sodium is widely used in lipidomics research to analyze lipid metabolism in cells.

HY-120964S

N-Stearoyl Taurine-d4	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
N-Stearoyl Taurine-d₄ is the deuterium labeled N-Stearoyl taurine (HY-120964). N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling .

HY-120965S

N-Palmitoyl Taurine-d4	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
N-Palmitoyl taurine-d₄ is the deuterium labeled N-Palmitoyl taurine (HY-120965). N-Palmitoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Its function is currently under investigation .

HY-157695

1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC	Endogenous Metabolite	Others
1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.

HY-165095

1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol 1,2-Palmitolein-3-palmitin; TG(16:1/16:1/16:0)	Others	Others
1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol (1,2-Palmitolein-3-palmitin) is a triglyceride used for serum lipidomics analysis by liquid chromatography-mass spectrometry. This method can effectively separate and detect lipids in positive and negative ionization modes and has certain performance in the identification and characterization of serum triglycerides.

HY-120963

N-Oleoyl Taurine	Endogenous Metabolite	Metabolic Disease
Several different arachidonoyl amino acids, including N-arachidonoyl dopamine and N-arachidonoyl serine, have been isolated and characterized from bovine brain.1 During mass spectral lipidomics analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, were discovered.2 This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3 N-Oleoyl taurine is an amino-acyl endocannabinoid isolated from rat brain that may activate TRPV1 and TRPV4.

HY-W414548

7α,27-Dihydroxycholesterol	Others	Neurological Disease Metabolic Disease
7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).

HY-126720

N-Lignoceroyl Taurine	Endogenous Metabolite	Metabolic Disease
N-Lignoceroyl Taurine is an arachidonoyl amino acid and taurine conjugate with a fatty acid that can be isolated from bovine brain. N-Lignoceroyl Taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of the brain and spinal cord of wild-type and fatty acid amide hydrolase (FAAH) knockout mice. N-Lignoceroyl Taurine levels were 23-26-fold higher in FAAH ^-/- mice compared to wild-type mice, suggesting that FAAH utilizes N-Lignoceroyl Taurine as a substrate. However, in vitro experiments with purified FAAH showed that N-Lignoceroyl Taurine was hydrolyzed 2,000-fold slower in FAAH compared to oleoylethanolamide. N-Acyl Taurines with polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) calcium channel family, including TRPV1 and TRPV4.

Cat. No.	Product Name

HY-L214

Liposome Library	138 compounds
Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components. MCE contains 138 liposome compounds, which is a good tool for lipidomic-related studies.

Liposome Library

138 compounds

Liposomes are spherical or multilayered spherical vesicles formed by the self-assembly of diacyl chain phospholipids (lipid bilayers) in aqueous solutions, which can be made from natural or synthetic phospholipids and exhibit good biocompatibility and low toxicity. They can serve as delivery carriers for various bioactive substances (such as drugs, proteins, nucleic acids, etc.) and are widely used in biomedical and chemical research. The main advantages of liposomes include 1) Protective effect: Their bilayer structure can protect encapsulated molecules from enzymatic degradation, oxidation, and other influences, extending stability and activity; 2) Active targeting: Surface modifications enable active targeting, enhancing the concentration of drugs or molecules in specific tissues or cells; 3) Customizability: The composition and structure of liposomes can be adjusted according to needs, such as altering phospholipid types or adding targeting ligands. These properties make liposomes highly valuable in developing novel drug delivery systems, serving as nucleic acid carriers for gene transfection, studying cellular uptake mechanisms and drug release kinetics, as well as developing functional food additives to improve the bioavailability of nutritional components.

MCE contains 138 liposome compounds, which is a good tool for lipidomic-related studies.

Cat. No.	Product Name	Type

HY-W329357

15:0 Lyso PC 1 Publications Verification	Drug Delivery
15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .

15:0 Lyso PC

1 Publications Verification

Drug Delivery

15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease .

Cat. No.	Product Name	Chemical Structure

HY-120964S

N-Stearoyl Taurine-d4
N-Stearoyl Taurine-d₄ is the deuterium labeled N-Stearoyl taurine (HY-120964). N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling .

HY-120965S

N-Palmitoyl Taurine-d4
N-Palmitoyl taurine-d₄ is the deuterium labeled N-Palmitoyl taurine (HY-120965). N-Palmitoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Its function is currently under investigation .

Cat. No.	Product Name		Classification

HY-157620

18:0 Lyso PS sodium		Phospholipids
18:0 Lyso PS sodium is a bioactive molecule with the activity of promoting cell signaling. 18:0 Lyso PS sodium plays an important role in regulating the fluidity and integrity of cell membranes. 18:0 Lyso PS sodium is widely used in lipidomics research to analyze lipid metabolism in cells.

HY-157695

1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC		Phospholipids
1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.

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