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Results for "

lipid transport

" in MedChemExpress (MCE) Product Catalog:

25

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2

Fluorescent Dye

6

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2

Peptides

2

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2

Isotope-Labeled Compounds

1

Click Chemistry

6

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-119770
    HDL376

    SDZ-HDL 376

    		 Scavenger Receptor Class B type I (SR-BI） Cardiovascular Disease
    HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease .
    HDL376
  • HY-116767
    BLT-1
    3 Publications Verification

    Block lipid transport-1

    		 HCV Metabolic Disease Inflammation/Immunology
    BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .
    BLT-1
  • HY-156237
    Beclin1-ATG14L interaction inhibitor 1
    1 Publications Verification

    		 Autophagy Others
    Beclin1-ATG14L interaction inhibitor 1 (com 19) is a selective Beclin1-ATG14L interaction inhibitor. This protein interaction mechanism specifically targets complex I of the lipid kinase VPS34 without affecting complex II. Because the integrity of VPS34 complex II depends on the Beclin 1-UVRAG interaction. Beclin1-ATG14L interaction inhibitor 1 can disrupt the formation of VPS34 complex I and inhibit autophagy, but does not affect complex II-related vesicle transport .
    Beclin1-ATG14L interaction inhibitor 1
  • HY-126912A
    Lauroyl coenzyme A lithium

    		Biochemical Assay Reagents Endogenous Metabolite Others
    Lauroyl coenzyme A lithium salt is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. Lauroyl coenzyme A lithium salt is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds.
    Lauroyl coenzyme A lithium
  • HY-139533
    Phosphatidylinositols, soya, sodium salts

    		Biochemical Assay Reagents Others
    Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics .
    Phosphatidylinositols, soya, sodium salts
  • HY-153136
    LNP Lipid-1

    		Liposome Others
    LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .
    LNP Lipid-1
  • HY-D1595
    BODIPY FL Cholesterol

    		Fluorescent Dye Others
    BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .
    BODIPY FL Cholesterol
  • HY-E70256
    12:0 Coenzyme A

    Lauroyl coenzyme A triammonium

    		 Biochemical Assay Reagents Endogenous Metabolite Others
    12:0 Coenzyme A (Lauroyl coenzyme A triammonium) is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. 12:0 Coenzyme A is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds .
    12:0 Coenzyme A
  • HY-N9610
    Coenzyme Q6

    Ubiquinone 30

    		 Endogenous Metabolite Inflammation/Immunology
    Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage .
    Coenzyme Q6
  • HY-B2078
    Eprazinone

    		Neurokinin Receptor Inflammation/Immunology
    Eprazinone can enhance lung function and arterial oxygen levels and can be used in the study of chronic bronchitis. Higher doses of eprazinone increased phospholipid levels and decreased neutral lipid content in bronchoalveolar lavage (BAL) fluid, but had no effect on protein and cell levels in BAL. Eprazinone dose-dependently reduced short-circuit current (Isc), primarily by reducing chloride secretion at lower concentrations and affecting sodium and chloride transport at higher doses. Eprazinone may exert its anti-inflammatory effects by regulating BAL lipid composition and airway ion transport .
    Eprazinone
  • HY-118534
    Cyclobutyrol

    BRN-2209058

    		 Endogenous Metabolite Endocrinology
    Cyclobutyrol is a potent choleretic agent. Cyclobutyrol also inhibits biliary lipid secretion. Cyclobutyrol induces choleretic is unrelated to bile acids. Cyclobutyrol and bile acids do not compete for the hepatobiliar transport mechanisms[1]
    Cyclobutyrol
  • HY-113736
    Glycyllysine

    		Amino Acid Derivatives Others
    Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
    Glycyllysine
  • HY-118534A
    Cyclobutyrol sodium

    BRN-2209058 sodium

    		 Endogenous Metabolite Endocrinology
    Cyclobutyrol sodium is a potent choleretic agent. Cyclobutyrol sodium also inhibits biliary lipid secretion. Cyclobutyrol sodium induces choleretic is unrelated to bile acids. Cyclobutyrol sodium and bile acids do not compete for the hepatobiliar transport mechanisms[1]
    Cyclobutyrol sodium
  • HY-154974
    LNP Lipid-8

    		Liposome Cancer
    LNP Lipid-8 (11-A-M) is an ionizable single-tail multi-head lipid that can be used as a lipid nanoparticle (LNP) to deliver siRNA to T cells without targeting ligands. LNP Lipid-8 is more selective for T cells than other cell types such as hepatocytes. LNP Lipid-8 selectively delivers siRNA/sgRNA to T cells (especially CD8 + T cells) through endogenous lipid transport pathways, and can enter cells and release RNA through endocytosis to achieve gene silencing. LNP Lipid-8 loaded with GFP siRNA (siGFP) significantly led to GFP gene silencing in mouse models. LNP Lipid-8 showed good efficacy and safety in both cells and animals, without obvious liver targeting and toxicity. LNP Lipid-8 can be used for RNA delivery research in the fields of tumor immunotherapy and T cell-mediated autoimmune diseases .
    LNP Lipid-8
  • HY-148842
    C14-4

    		Liposome Others
    C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
    C14-4
  • HY-113217
    Cholesteryl oleate

    		Liposome Endogenous Metabolite Metabolic Disease Cancer
    Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
    Cholesteryl oleate
  • HY-129990
    Dios-Arg diTFA

    		Liposome Cancer
    Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport .
    Dios-Arg diTFA
  • HY-113217S
    Cholesteryl oleate-d7

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
    Cholesteryl oleate-d7
  • HY-D1617
    BODIPY 500/510 C1, C12

    		Fluorescent Dye Others
    BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20℃.
    BODIPY 500/510 C1, C12
  • HY-120103
    PF-06649298

    		Sodium Channel Metabolic Disease
    PF-06649298 is a sodium-coupled citrate transporter (NaCT or SLC13A5) inhibitor. PF-06649298 specifically interacts with NaCT with an IC50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used for the research of regulating glucose metabolism and lipid metabolism .
    PF-06649298
  • HY-113217S1
    Cholesteryl oleate-d7-1

    		Isotope-Labeled Compounds Endogenous Metabolite Others
    Cholesteryl oleate-d7-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
    Cholesteryl oleate-d7-1
  • HY-W782122
    Photoclick cholesterol

    		Biochemical Assay Reagents Others
    Photoclick cholesterol is a sterol lipid cholesterol analog that contains a clickable terminal alkyne moiety and a photoactivatable diaziridine group. Photoclick cholesterol has the ability to photoaffinity label the mitochondrial outer membrane transport protein (TSPO) and is able to specifically bind cholesterol to TSPO. However, using excessive amounts of Photoclick cholesterol will reduce the photolabeling of total mitochondrial proteins and TSPO .
    Photoclick cholesterol
  • HY-153229
    Firefly luciferase mRNA-LNP

    		Biochemical Assay Reagents Others
    Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .
    Firefly luciferase mRNA-LNP
  • HY-P3394
    Cholera toxin B subunit, from vibrio cholerae

    CTB, from vibrio cholerae

    		 Biochemical Assay Reagents Others
    Cholera toxin B subunit, from vibrio cholerae (CTB, from vibrio cholerae) is non-toxic to cells and possesses no intrinsic adenylate cyclase activity. Cholera toxin B subunit, from vibrio cholerae attaches to cells by binding to ganglioside GM1.8 CTB has been shown to be a good label for microglial cells (due to the enrichment of ganglioside GM1 on their cell surface), but not for oligodendrocytes or astrocytes. Cholera toxin B subunit, from vibrio cholerae has been reported to be an excellent tracer for the study of axonal transport using immunohistochemical methods. Cholera toxin B subunit, from vibrio cholerae has been widely used as a marker of membrane lipid rafts .
    Cholera toxin B subunit, from vibrio cholerae
  • HY-18282
    AZ876

    		LXR Cardiovascular Disease Metabolic Disease Cancer
    AZ876 is a selective, orally active agonist of liver X receptor (LXRα/β) (Ki=0.007 μM [LXRα, human], 0.011 μM [LXRβ, human]. AZ876 induces the expression of target genes such as ABCA1 and ABCG1, promotes reverse cholesterol transport (RCT) and regulates lipid metabolism and anti-inflammatory effects. AZ876 increases cardiac polyunsaturated fatty acid levels, reduces myocardial fibrosis, and reduces lesion area and monocyte adhesion in atherosclerosis models. AZ876 can be used in cardiovascular disease research, such as preventing and treating β-adrenergic-induced cardiac diastolic dysfunction and inhibiting the progression of atherosclerosis .
    AZ876

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