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linoleic acid diol

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131670
    (±)9,10-DiHOME

    		AP-1 PPAR NF-κB Inflammation/Immunology
    (±)9,10-DiHOME is the racemate of 9,10-DiHOME. 9,10-DiHOME is a leukotoxin derivative of linoleic acid diol that has been reported to be toxic in human's tissue preparations, and is produced by inflammatory leukocytes such as neutrophils and macrophages .
    (±)9,10-DiHOME
  • HY-W713416
    Isoleukotoxin diol

    		Biochemical Assay Reagents Others
    Isoleukotoxin Diol is the oxidation product of linoleic acid, with a pair of hydroxly groups on the unsaturated fatty acid tail and a carboxylic acid as the polar head.
    Isoleukotoxin diol
  • HY-W749980A
    cis-Coronaric acid

    cis-9,10-Epoxy-12(Z)-octadecenoic acid

    		 Endogenous Metabolite Others
    cis-Coronaric acid is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. It has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome. Mitochondrial dysfunction is the main feature of cis-Coronaric acid cytotoxicity, which may be due to the diol metabolites as well as the parent epoxide.
    cis-Coronaric acid

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