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Results for "

limb development

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132971
    Thalidomide-piperazine hydrochloride

    		Molecular Glues Ligands for E3 Ligase Autophagy Apoptosis Cancer
    Thalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development .
    Thalidomide-piperazine hydrochloride
  • HY-16268A
    Kartogenin sodium
    25+ Cited Publications

    KGN sodium

    		 TGF-beta/Smad Inflammation/Immunology
    Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation (EC50: 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .
    Kartogenin sodium
  • HY-16268
    Kartogenin
    25+ Cited Publications

    KGN

    		 TGF-beta/Smad Inflammation/Immunology
    Kartogenin (KGN) is an inducer of chondrogenic tissue formation (EC50: 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research .
    Kartogenin
  • HY-174477
    Mouse Tbx5 mRNA

    		mRNA Cardiovascular Disease
    Mouse Tbx5 mRNA encodes the mouse T-box 5 (Tbx5) protein, a DNA-binding protein that regulates the transcription of several genes. Tbx5 is involved in heart development and limb pattern formation.
    Mouse Tbx5 mRNA
  • HY-174538
    Human TBX5 mRNA

    		mRNA Cardiovascular Disease
    Human TBX5 mRNA encodes the human T-box transcription factor 5 (TBX5) protein, a member of a phylogenetically conserved family. TBX5 is a DNA-binding protein that regulates the transcription of several genes and also involved in heart development and limb pattern formation.
    Human TBX5 mRNA
  • HY-174554
    Human PAX9 mRNA

    		mRNA Cancer
    Human PAX9 mRNA encodes the human paired box 9 (PAX9) protein, a member of the paired box (PAX) family. PAX9 is required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
    Human PAX9 mRNA
  • HY-174702
    Human FGF2 mRNA

    		mRNA Neurological Disease
    Human FGF2 mRNA encodes the human fibroblast growth factor 2 (FGF2) protein, a member of the fibroblast growth factor (FGF) family. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth.
    Human FGF2 mRNA

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