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Results for "

laxative

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

3

Biochemical Assay Reagents

1

Peptides

7

Natural
Products

1

Isotope-Labeled Compounds

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6070
    Ricinoleic acid (purity≥85%)

    		Prostaglandin Receptor Inflammation/Immunology
    Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
    Ricinoleic acid (purity≥85%)
  • HY-P3499
    Dolcanatide

    		Guanylate Cyclase Inflammation/Immunology
    Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .
    Dolcanatide
  • HY-107799
    Castor oil
    2 Publications Verification

    		 Biochemical Assay Reagents Others
    Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
    Castor oil
  • HY-101714
    Oxyphenisatin acetate

    		Autophagy Cancer
    Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative.
    Oxyphenisatin acetate
  • HY-B2134
    Casanthranol

    		Others Metabolic Disease
    Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions .
    Casanthranol
  • HY-W326021
    Phenolphthalol

    		Estrogen Receptor/ERR Endocrinology
    Phenolphthalol is a laxative in agent preparations and also estrogenically active .
    Phenolphthalol
  • HY-117749
    Bisoxatin acetate

    WY 8138; DB09219 acetate

    		 Angiotensin-converting Enzyme (ACE) SARS-CoV Metabolic Disease
    Bisoxatin (WY 8138; DB09219) acetate is a laxative agent. Bisoxatin acetate is a stimulant for intestinal peristalsis and has the potential for the research of constipation disorder .
    Bisoxatin acetate
  • HY-121068
    Bisoxatin

    		Angiotensin-converting Enzyme (ACE) SARS-CoV Infection
    Bisoxatin is a laxative drug used for constipation. Bisoxatin binds substantially at the S-protein-ACE2 interface. Bisoxatin has the potential for inhibiting SARS-CoV-2 entry into the host research .
    Bisoxatin
  • HY-122307
    Sulisatin

    DAN-603

    		 Bacterial Metabolic Disease
    Sulisatin (DAN-603) is an anionic laxative that is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon during oral administration .
    Sulisatin
  • HY-121068R
    Bisoxatin (Standard)

    		Angiotensin-converting Enzyme (ACE) SARS-CoV Infection
    Bisoxatin (Standard) is the analytical standard of Bisoxatin. This product is intended for research and analytical applications. Bisoxatin is a laxative drug used for constipation. Bisoxatin binds substantially at the S-protein-ACE2 interface. Bisoxatin has the potential for inhibiting SARS-CoV-2 entry into the host research .
    Bisoxatin (Standard)
  • HY-B2102
    Oxyphenisatine

    Oxyphenisatin

    		 Drug Derivative Cancer
    Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.
    Oxyphenisatine
  • HY-B0557
    Bisacodyl

    		Dopamine Transporter Opioid Receptor Metabolic Disease Cancer
    Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
    Bisacodyl
  • HY-101714R
    Oxyphenisatin acetate (Standard)

    		Autophagy Cancer
    Oxyphenisatin acetate (Standard) is the analytical standard of Oxyphenisatin acetate. This product is intended for research and analytical applications. Oxyphenisatin acetate, the pro-agent of oxyphenisatin, is used to be a laxative.
    Oxyphenisatin acetate (Standard)
  • HY-B0557R
    Bisacodyl (Standard)

    		Dopamine Transporter Opioid Receptor Metabolic Disease Cancer
    Bisacodyl (Standard) is the analytical standard of Bisacodyl. This product is intended for research and analytical applications. Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect .
    Bisacodyl (Standard)
  • HY-B2102R
    Oxyphenisatine (Standard)

    		Drug Derivative Cancer
    Oxyphenisatine (Standard) is the analytical standard of Oxyphenisatine. This product is intended for research and analytical applications. Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.
    Oxyphenisatine (Standard)
  • HY-N12326
    Multiflorin A

    		Bacterial Others
    Multiflorin A is an active ingredient derived from Pruni semen. Multiflorin A has laxative activity. Multiflorin A inhibits intestinal glucose absorption and promotes bacterial metabolism .
    Multiflorin A
  • HY-B0544
    Sodium Picosulfate

    Sodium Picosulphate

    		 Others Metabolic Disease
    Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .
    Sodium Picosulfate
  • HY-Y0332C
    Phosphoric acid (sodium hydrate),≥99.0%
    1 Publications Verification

    Sodium phosphate dihydrate,≥99.0%

    		 Biochemical Assay Reagents Others
    Phosphoric acid (sodium hydrate),≥99.0% is used as a buffer capacity reagent in molecular biology, biochemistry, and chromatography. For the preparation of biological buffers. It is also used to purify antibodies, as a laxative, and in combination with other sodium phosphates
    Phosphoric acid (sodium hydrate),≥99.0%
  • HY-131637
    Desacetyl bisacodyl

    		Drug Metabolite Metabolic Disease
    Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion .
    Desacetyl bisacodyl
  • HY-107793
    Picosulfate sodium salt hydrate

    		Drug Derivative Metabolic Disease
    Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications .
    Picosulfate sodium salt hydrate
  • HY-135319
    Strictinin

    		Bacterial Antibiotic Infection
    Strictinin is a phenolic compound isolated from Pu'er teas. Strictinin has potential antiviral, antibacterial and laxative activities. Strictinin occurs by accelerating intestinal transit rather than enhancing gastric emptying, increasing food intake, or inducing diarrhea in rats.
    Strictinin
  • HY-Y0308
    Disodium phosphate

    		Biochemical Assay Reagents Others
    Disodium phosphate is commonly used as a food additive, buffer and laboratory reagent. Disodium phosphate has unique chemical properties that make it an important ingredient in the manufacture of fertilizers, detergents and water treatment products. Additionally, it is used in various medical applications such as osmotic laxatives and electrolyte replacement solutions.
    Disodium phosphate
  • HY-W105835
    Magnesium citrate

    Trimagnesium dicitrate

    		 Toll-like Receptor (TLR) Neurological Disease
    Magnesium citrate (Trimagnesium dicitrate) is an orally active magnesium-containing compound that can cross the blood-brain barrier (BBB). Magnesium citrate can be used as an intestinal cleanser and is studied for its application in laxatives. Magnesium citrate can also increase the pain threshold and is studied for pain-relief purposes .
    Magnesium citrate
  • HY-131637R
    Desacetyl bisacodyl (Standard)

    		Drug Metabolite Metabolic Disease
    Desacetyl bisacodyl (Standard) is the analytical standard of Desacetyl bisacodyl. This product is intended for research and analytical applications. Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion .
    Desacetyl bisacodyl (Standard)
  • HY-122307A
    Sulisatin disodium

    DAN-603 disodium

    		 Bacterial Metabolic Disease
    Sulisatin (DAN-603) disodium is an anionic diarrhea-promoting compound. During oral administration, Sulisatin disodium is hydrolyzed to diphenolic derivatives by bacterial aryl sulfate sulfohydrolases in the colon .
    Sulisatin disodium
  • HY-N0108S
    Physcion-d3

    Parietin-d3; Rheochrysidin-d3

    		 Isotope-Labeled Compounds Bacterial Infection Inflammation/Immunology Cancer
    Physcion-d3 (Parietin-d3) is the deuterium labeled Physcion (HY-N0108). Physcion acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .
    Physcion-d3
  • HY-167825
    Barakol

    		MMP Apoptosis Bcl-2 Family Reactive Oxygen Species Neurological Disease Inflammation/Immunology Cancer
    Barakol is a major compound found in Cassia siamea. Barakol inhibits MMP-3 activity. Barakol potentiates the anti-metastatic effect of Doxorubicin (HY-15142). Barakol induces apoptosis, with ROS generation, increase in expression ratio of Bax/Bcl-2, and caspase-9 activation. Barakol has laxative, anxiolytic, CNS depressant, and antioxidant, anticancer effects .
    Barakol
  • HY-N0108R
    Physcion (Standard)

    		Bacterial Infection Inflammation/Immunology Cancer
    Physcion (Standard) is the analytical standard of Physcion. This product is intended for research and analytical applications. Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively . Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects .
    Physcion (Standard)
  • HY-N6070A
    Ricinoleic acid (purity≥99%)

    		Prostaglandin Receptor Inflammation/Immunology
    Ricinoleic acid (purity≥99%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
    Ricinoleic acid (purity≥99%)
  • HY-N6070AR
    Ricinoleic acid (purity≥99%) (Standard)

    		Prostaglandin Receptor Inflammation/Immunology
    Ricinoleic acid (purity≥99%) (Standard) is the analytical standard of Ricinoleic acid (purity≥99%). This product is intended for research and analytical applications. Ricinoleic acid (purity≥99%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
    Ricinoleic acid (purity≥99%) (Standard)
  • HY-N6070R
    Ricinoleic acid (purity≥85%) (Standard)

    		Prostaglandin Receptor Inflammation/Immunology
    Ricinoleic acid (purity≥85%) (Standard) is the analytical standard of Ricinoleic acid (purity≥85%). This product is intended for research and analytical applications. Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties .
    Ricinoleic acid (purity≥85%) (Standard)

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