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Pathways Recommended: Protein Tyrosine Kinase/RTK
Results for "

inositol hexakisphosphate kinases

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153530
    LI-2242

    		IPK Superfamily Neurological Disease Metabolic Disease
    LI-2242 is an inositol hexakisphosphate kinase (IP6K) inhibitor. LI-2242 has inhibition effect for IP6K1, IP6K2, IP6K3 and IPMK with IC50 values of 31 nM, 42 nM, 8.7 nM and 1944 nM, respectively. LI-2242 can be used for thew research of type II diabetes, obesity, metabolic complications, venous thrombosis, and psychiatric disorders .
    LI-2242
  • HY-171099
    SC-919

    LI-2124

    		 IPK Superfamily Cardiovascular Disease
    SC-919 (LI-2124) is an orally active and selective inhibitor targeting inositol hexakisphosphate kinases (IP6K, including IP6K1, IP6K2, and IP6K3 subtypes) with an IC50 value of 0.65 nM for IP6K3. SC-919 reduces the production of inositol pyrophosphates (e.g., InsP₇) by inhibiting IP6K, thereby suppressing XPR1-mediated cellular phosphate export and increasing intracellular ATP levels. SC-919 is promising for research of chronic kidney disease (CKD)-related hyperphosphataemia .
    SC-919

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