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hydrogenolysis

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14

Inhibitors & Agonists

1

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W027631
    cis-2-Butene-1,4-diol

    		Fluorescent Dye Infection
    cis-2-Butene-1,4-diol, an industrial product, can be used for the synthesis of antiviral product oxetanocin A. cis-2-Butene-1,4-diol is a probe for studying isomerization versus hydrogenation and hydrogenolysis reactions .
    cis-2-Butene-1,4-diol
  • HY-17466
    Sancycline

    Bonomycin; 6-Demethyl-6-deoxytetracycline

    		 Bacterial Antibiotic Metabolic Disease Inflammation/Immunology
    Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .
    Sancycline
  • HY-17466A
    Sancycline hydrochloride

    Bonomycin hydrochloride; 6-Demethyl-6-deoxytetracycline hydrochloride

    		 Antibiotic Bacterial Metabolic Disease Inflammation/Immunology
    Sancycline (6-Demethyl-6-deoxytetracycline) hydrochloride acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline hydrochloride, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin .
    Sancycline hydrochloride
  • HY-W025371
    Dihydrosinapyl alcohol

    		Others Others
    Dihydrosinapyl alcohol, a natural product, can be obtained from lignocellulose by hydrogenation and hydrogenolysis .
    Dihydrosinapyl alcohol
  • HY-W451433
    OTs-PEG1-NHCbz

    		Biochemical Assay Reagents Others
    OTs-PEG1-NHCbz is a PEG linker containing a tosyl group and benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of the compound in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    OTs-PEG1-NHCbz
  • HY-17466R
    Sancycline (Standard)

    Bonomycin (Standard); 6-Demethyl-6-deoxytetracycline (Standard)

    		 Bacterial Antibiotic Metabolic Disease Inflammation/Immunology
    Sancycline (Standard) is the analytical standard of Sancycline. This product is intended for research and analytical applications. Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin[1][2][3].
    Sancycline (Standard)
  • HY-N9903
    Tetrahydrodehydrodiconiferyl alcohol

    TDDC

    		 Others Others
    Tetrahydrodehydrodiconiferyl alcohol (TDDC) is a reduction product of dihydrodehydrodiconiferyl alcohol catalyzed by phenylcoumaran benzylic ether reductase. Tetrahydrodehydrodiconiferyl alcohol can be isolated from a hydrogenolysis product of protolignin .
    Tetrahydrodehydrodiconiferyl alcohol
  • HY-W800684
    Benzyloxy carbonyl-PEG4-NHS ester

    		Biochemical Assay Reagents Others
    Benzyloxy carbonyl-PEG4-NHS ester is a reagent with a benzyl protecting group and an NHS ester. The NHS ester reacts with primary amines (-NH2). The benzyl protecting group can be removed by hydrogenolysis.
    Benzyloxy carbonyl-PEG4-NHS ester
  • HY-W800681
    Benzyloxy carbonyl-PEG4-acid

    		Biochemical Assay Reagents Others
    Benzyloxy carbonyl-PEG4-acid is a linker with a benzyl protecting group and a carboxylic acid. The carboxylic acid can undergo reactions with primary amines with the help of activators (EDC or HATU). The benzyl protecting group can be removed via hydrogenolysis.
    Benzyloxy carbonyl-PEG4-acid
  • HY-W591969
    Benzyl (6-oxohexyl)carbamate

    		Biochemical Assay Reagents Others
    Benzyl (6-oxohexyl)carbamate is a linker containing an aldehyde group and a benzyl (Cbz) protecting group. The aldehyde can react with hydrazine or hydrazide to form a hydrolytic acyl hydrozone linkage. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    Benzyl (6-oxohexyl)carbamate
  • HY-W160298
    N-Cbz-7-Aminoheptanoic acid

    		Biochemical Assay Reagents Others
    N-Cbz-7-Aminoheptanoic acid is a six carbon linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    N-Cbz-7-Aminoheptanoic acid
  • HY-W403327
    CbzNH-PEG4-CH2COOH

    		Biochemical Assay Reagents Others
    CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    CbzNH-PEG4-CH2COOH
  • HY-W348348
    CbzNH-PEG3-CH2CH2NH2

    		Biochemical Assay Reagents Others
    CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    CbzNH-PEG3-CH2CH2NH2
  • HY-P10563
    Noraramtide

    BHV-1100

    		 CD38 Cancer
    Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
    Noraramtide

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