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Results for "

endosomolytic peptide

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Peptides

Cat. No. Product Name Target Research Area
  • HY-P4121
    L17E

    		Potassium Channel Inflammation/Immunology Cancer
    L17E is an attenuated cationic amphiphilic lytic (ACAL) peptide that can be used to deliver a variety of macromolecules, including proteins, antibodies, and DNA nanostructures. L17E inserts and cleaves the membrane structure through electrostatic interaction, enabling intracellular escape. The efficiency of L17E-mediated delivery is strongly correlated with the expression level of KCNN4 (the gene encoding the calcium-activated potassium channel KCa3.1). L17E also promotes the cellular uptake of macromolecules by inducing micropinocytosis. L17E can be further optimized and improved through dimerization strategies and in combination with other delivery systems, such as nuclear localization signal peptides and cell membrane-coated nanoparticles .
  • HY-169756
    L17E-OH

    		Peptides Others
    L17E-OH is a derived peptide of L17E, an endosomolytic peptide, a cationic amphipathic peptide with specific membrane lytic activity against late endosomes (Les) .

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