Search Result

Results for "

electron transport

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) Antibiotic (3) Apoptosis (13) ATP Synthase (3) Autophagy (2) Bacterial (8) Biochemical Assay Reagents (9) Cytochrome P450 (2) Disulfidptosis (1) Drug Intermediate (1) Endogenous Metabolite (8) Enterovirus (3) Ferroptosis (4) Fungal (2) GABA Receptor (2) GLUT (1) Glycosidase (1) Herbicide (4) Influenza Virus (4) Insecticide (3) Isotope-Labeled Compounds (6) Keap1-Nrf2 (2) Mitochondrial Metabolism (21) Na+/K+ ATPase (2) Oxidative Phosphorylation (2) Parasite (7) Photosystem II (4) Pyruvate Kinase (1) Reactive Oxygen Species (11) Reference Standards (3) Topoisomerase (1) Virus Protease (1)
By Research Areas:	Cancer (22) Cardiovascular Disease (4) Endocrinology (2) Infection (28) Inflammation/Immunology (6) Metabolic Disease (12) Neurological Disease (7)

By Targets:

ADC Cytotoxin (1)

Antibiotic (3)

Apoptosis (13)

ATP Synthase (3)

Autophagy (2)

Bacterial (8)

Biochemical Assay Reagents (9)

Cytochrome P450 (2)

Disulfidptosis (1)

Drug Intermediate (1)

Endogenous Metabolite (8)

Enterovirus (3)

Ferroptosis (4)

Fungal (2)

GABA Receptor (2)

GLUT (1)

Glycosidase (1)

Herbicide (4)

Influenza Virus (4)

Insecticide (3)

Isotope-Labeled Compounds (6)

Keap1-Nrf2 (2)

Mitochondrial Metabolism (21)

Na+/K+ ATPase (2)

Oxidative Phosphorylation (2)

Parasite (7)

Photosystem II (4)

Pyruvate Kinase (1)

Reactive Oxygen Species (11)

Reference Standards (3)

Topoisomerase (1)

Virus Protease (1)

By Research Areas:

Cancer (22)

Cardiovascular Disease (4)

Endocrinology (2)

Infection (28)

Inflammation/Immunology (6)

Metabolic Disease (12)

Neurological Disease (7)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: FATP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114197

Antimalarial agent 14	Mitochondrial Metabolism Parasite	Infection
Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent .

HY-130055

HQNO 1 Publications Verification	Mitochondrial Metabolism	Infection
HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a K_d of 64 nM for complex III . HQNO is a potent inhibitor of mitochondrial NDH-2 in many species .

HY-112177

Myxothiazol	Fungal Mitochondrial Metabolism Antibiotic	Infection
Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .

HY-N6782

Oligomycin 55+ Cited Publications	Oxidative Phosphorylation ATP Synthase Fungal Antibiotic	Infection Cancer
Oligomycin, an antifungal antibiotic, is an inhibitor of H ⁺-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells .

HY-121242

Buthidazole VEL-5026	Photosystem II	Others
Buthidazole is a selective herbicide for weed control in corn. Buthidazole inhibits photosynthetic electron transport at two distinct sites in the photosynthetic electron transport chain. The major site of inhibition was on the reducing side of photosystem II. Another site of electron transport inhibition is on the oxidizing side of photosystem II. Buthidazole inhibits corn photosynthesis and prevents starch accumulation in bundle sheath chloroplasts and some ultrastructural disruption of mesophyl chloroplasts of corn plants .

HY-N11913

Siderin	Biochemical Assay Reagents	Others
Siderin is a Photosystem II inhibitor that effectively inhibits ATP synthesis and chloroplast electron transport during photosynthesis in isolated spinach. Siderin can be used in the study of plant photosynthesis .

HY-B1849

Hexazinone	Herbicide	Infection
Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .

HY-N10094

Maculosidine	Others	Others
Maculosidine is a furoquinoline alkaloid that can be isolated from Balfourodendron riedelianum. Maculosidine inhibits ATP synthesis, basal, phosphorylating and uncoupled electron transport in plants. Maculosidine inhibits Hill reaction on spinach chloroplasts .

HY-130055R

HQNO (Standard)	Mitochondrial Metabolism	Infection
HQNO (Standard) is the analytical standard of HQNO. This product is intended for research and analytical applications. HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].

HY-B1849R

Hexazinone (Standard)	Herbicide	Infection
Hexazinone (Standard) is the analytical standard of Hexazinone. This product is intended for research and analytical applications. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .

HY-101415

Coenzyme Q9 Ubiquinone Q9; CoQ9; Ubiquinone 9	Apoptosis Endogenous Metabolite	Cardiovascular Disease
Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-126222

MitoTam bromide, hydrobromide	Apoptosis Mitochondrial Metabolism	Cancer
MitoTam bromide, hydrobromide, a Tamoxifen derivative , is an electron transport chain (ETC) inhibitor. MitoTam bromide, hydrobromide reduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology . MitoTam bromide, hydrobromide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells .

HY-126222A

MitoTam iodide, hydriodide	Apoptosis Mitochondrial Metabolism	Cancer
MitoTam iodide, hydriodide is a Tamoxifen derivative , an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology . MitoTam iodide, hydriodide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells . MitoTam iodide, hydriodide causes apoptosis .

HY-101415R

Coenzyme Q9 (Standard) Ubiquinone Q9 (Standard); CoQ9 (Standard); Ubiquinone 9 (Standard)	Reference Standards Apoptosis Endogenous Metabolite	Cardiovascular Disease
Coenzyme Q9 (Standard) is the analytical standard of Coenzyme Q9. This product is intended for research and analytical applications. Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-118675

L-erythro-Chloramphenicol	Drug Intermediate Bacterial	Others
L-erythro-Chloramphenicol acts as a powerful inhibitor of electron transport.

HY-N0111

Coenzyme Q10 5+ Cited Publications CoQ10; Ubiquinone-10; Ubidecarenone	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1756

Rotenone Maximum Cited Publications 97 Publications Verification	Mitochondrial Metabolism Autophagy Apoptosis	Neurological Disease Cancer
Rotenone is a *mitochondrial electron* transport chain complex I** inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.

HY-120338

RYL-552	Mitochondrial Metabolism Parasite	Infection
RYL-552, a *mitochondrial electron* transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2)** inhibtor .

HY-121214

Amisulbrom	Mitochondrial Metabolism	Infection
Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom biochemically inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system .

HY-125857B

Cytochrome C (Saccharomyces cerevisiae)	Biochemical Assay Reagents Apoptosis	Metabolic Disease
Cytochrome C (Saccharomyces cerevisiae) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (Saccharomyces cerevisiae) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (Saccharomyces cerevisiae) can act as a single electron carrier .

HY-125857C

Cytochrome C (bovine heart)	Biochemical Assay Reagents Apoptosis	Metabolic Disease
Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .

HY-125857A

Cytochrome C (equine heart)	Biochemical Assay Reagents Apoptosis	Metabolic Disease
Cytochrome C (equine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (equine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (equine heart) can act as a single electron carrier .

HY-125857

Cytochrome C	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species	Metabolic Disease
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .

HY-136406

Bongkrekic acid	ATP Synthase	Infection Cancer
Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans . Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .

HY-119984

DNP-INT	Cytochrome P450	Others
DNP-INT is a potent photosynthetic electron transport chain (PETC) inhibitor. DNP-INT competently inhibits the oxidation of plastid quinoline by binding to the Q0 site of Cyt-b6f (Kd=1.4 nM), thereby inhibiting electron transfer in plants .

HY-D0937

Methoxy-PMS 3 Publications Verification 1-Methoxy PMS; 1-Methoxyphenazine methosulfate	Reactive Oxygen Species	Others
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes .

HY-162515

8-OAc	Mitochondrial Metabolism	Cancer
8-OAc is a potent and selective mitochondrial electron transport chain (ETC) complex I inhibitor. 8-OAc exhibits cytotoxicity against cancer cell lines .

HY-13834

GW844520	Parasite Cytochrome P450	Infection
GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research .

HY-N0111S2

Coenzyme Q10-d9 CoQ10-d₉; Ubiquinone-10-d₉	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-17513

Amicarbazone BAY314666; BAY-MKH 3586	Herbicide	Others
Amicarbazone (BAY-MKH3586; BAY314666) becomes an effective inhibitor of photosynthetic electron transport by binding to the Qb site of photosystem II (PSII); it is a herbicide with broad-spectrum weed control.

HY-N0111S

Coenzyme Q10-d6 CoQ10-d₆; Ubiquinone-10-d₆	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10-d₆ is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-158421

MS-L6	Oxidative Phosphorylation Mitochondrial Metabolism	Cancer
MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect .

HY-N0111R

Coenzyme Q10 (Standard)	Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10 (Standard) is the analytical standard of Coenzyme Q10. This product is intended for research and analytical applications. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-119687

Bifenazate	GABA Receptor Mitochondrial Metabolism Na+/K+ ATPase Reactive Oxygen Species Insecticide	Infection Cardiovascular Disease
Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm . Bifenazate is a positive allosteric modulator of GABA receptor . Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III .

HY-B1756R

Rotenone (Standard)	Mitochondrial Metabolism Autophagy Apoptosis	Neurological Disease Cancer
Rotenone (Standard) is the analytical standard of Rotenone. This product is intended for research and analytical applications. Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.

HY-B1849S

Hexazinone-d6	Isotope-Labeled Compounds	Infection
Hexazinone-d₆ is the deuterium labeled Hexazinone . Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .

HY-136406S

Bongkrekic acid-13C28	Isotope-Labeled Compounds ATP Synthase	Cancer
Bongkrekic acid- ¹³C₂₈ is the ¹³C labeled Bongkrekic acid (HY-136406). Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .

HY-121214R

Amisulbrom (Standard)	Mitochondrial Metabolism	Infection
Amisulbrom (Standard) is the analytical standard of Amisulbrom. This product is intended for research and analytical applications. Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom biochemically inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system .

HY-149998

Antimycobacterial agent-5	Bacterial Reactive Oxygen Species Apoptosis	Infection
Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide targeting mycobacterial electron transport chain (ETC) airway CIII₂CIV₂ supercomplexes. The IC₅₀ value of Antimycobacterial agent-5 against Mycobacterium smegmatisCIII₂CIV₂ is 441 nM .

HY-N9610

Coenzyme Q6 Ubiquinone 30	Endogenous Metabolite	Inflammation/Immunology
Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage .

HY-121248

Hydramethylnon AC217300	Mitochondrial Metabolism	Infection
Hydramethylnon (AC217300) is an amidinohydrazone insecticide. Hydramethylnon's mechanism of action is through inhibition of mitochondrial respiration by inhibiting the electron transport chain at the cytochrome b-c1 complex. Hydramethylnon can be used to eliminate red imported fire ants, cockroaches, and other insects .

HY-155849

PKM2-IN-4	Pyruvate Kinase	Cancer
Pkm2-in-4 (compound 5C) is a selective inhibitor of PKM2 (IC₅₀=0.35 μM), which regulates pyruvate-dependent respiration and induces mitochondrial H202 production rate and electron transport system coupling .

HY-119687R

Bifenazate (Standard)	Reference Standards GABA Receptor Mitochondrial Metabolism Na+/K+ ATPase Reactive Oxygen Species Insecticide	Infection Cardiovascular Disease
Bifenazate (Standard) is the analytical standard of Bifenazate. This product is intended for research and analytical applications. Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm . Bifenazate is a positive allosteric modulator of GABA receptor . Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III .

HY-W242709

4-Chloroquinolin-8-ol	Biochemical Assay Reagents	Others
4-Chloroquinolin-8-ol (compound 1) is an Alq3-derived aluminum ligand. Alq3 is an organometallic molecule widely used as electron transport layer and light-emitting layer in organic LEDs, and also as a host for fluorescent and phosphorescent dyes .

HY-B0817

Pyridaben	Parasite	Infection
Pyridaben is a *mitochondrial electron* transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS** function .

HY-125283

IM176OUT05	Mitochondrial Metabolism	Metabolic Disease
IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC₅₀ of 3.2 μM .

HY-170369

SHO1122147	Mitochondrial Metabolism	Metabolic Disease
SHO1122147 (Compound 7m) affects the mitochondrial electron transport chain, exhibits mitochondrial uncoupling activity (EC₅₀=3.6 μM), and increases the oxygen consumption rate (OCR=69%) and promotes cellular respiration. SHO1122147 is orally active, and can be used in reaearch of obesity and metabolic dysfunction-associated steatohepatitis (MASH) .

HY-N1839

3-Hydroxybakuchiol	Apoptosis Glycosidase	Cancer
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC₅₀: 345 μM) .

HY-19877

GSK932121	Parasite	Infection
GSK932121 is an antimalarial drug with activity that inhibits the electron transport chain of P. falciparum. GSK932121 acts selectively on this pathogen at the level of cytochrome bc1 (complex III). The synthesis method of GSK932121 is highly efficient, and the final structure can be obtained in only 5 steps. The synthesis of GSK932121 can be prepared atK_ilog scale to support clinical studies .

HY-B0817S

Pyridaben-d13	Parasite	Infection
Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

Cat. No.	Product Name	Type

HY-125857C

Cytochrome C (bovine heart)	Native Proteins
Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .

HY-125857

Cytochrome C	Cell Assay Reagents
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .

HY-D0937

Methoxy-PMS 3 Publications Verification 1-Methoxy PMS; 1-Methoxyphenazine methosulfate	Cell Assay Reagents
Methoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes .

HY-125857B

Cytochrome C (Saccharomyces cerevisiae)	Native Proteins
Cytochrome C (Saccharomyces cerevisiae) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (Saccharomyces cerevisiae) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (Saccharomyces cerevisiae) can act as a single electron carrier .

HY-125857A

Cytochrome C (equine heart)	Native Proteins
Cytochrome C (equine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (equine heart) is involved in mitochondrial electron transport and intrinsic type II apoptosis. Cytochrome C (equine heart) can act as a single electron carrier .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-130055

HQNO 1 Publications Verification	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Mitochondrial Metabolism
HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a K_d of 64 nM for complex III . HQNO is a potent inhibitor of mitochondrial NDH-2 in many species .

HY-112177

Myxothiazol	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Other Antibiotics	Fungal Mitochondrial Metabolism Antibiotic
Myxothiazol, an antifungal antibiotic, is a mitochondrial electron transport chain complex III (bc1 complex) inhibitor. Myxothiazol inhibits the growth of many yeasts and fungi at concentrations between 0.01 and 3 μg/ml .

HY-N6782

Oligomycin 55+ Cited Publications	Infection Structural Classification Microorganisms Antifungal Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields	Oxidative Phosphorylation ATP Synthase Fungal Antibiotic
Oligomycin, an antifungal antibiotic, is an inhibitor of H ⁺-ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells .

HY-101415

Coenzyme Q9 Ubiquinone Q9; CoQ9; Ubiquinone 9	Cardiovascular Disease Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Endogenous metabolite Disease Research Fields	Apoptosis Endogenous Metabolite
Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-N0111

Coenzyme Q10 5+ Cited Publications CoQ10; Ubiquinone-10; Ubidecarenone	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Metabolic Disease Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Benzene Quinones Inflammation/Immunology Disease Research Fields Cancer	Endogenous Metabolite Reactive Oxygen Species Ferroptosis
Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1756

Rotenone Maximum Cited Publications 97 Publications Verification	Structural Classification Flavonoids Neurological Disease Classification of Application Fields Leguminosae Derris trifoliata Lour. Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research	Mitochondrial Metabolism Autophagy Apoptosis
Rotenone is a *mitochondrial electron* transport chain complex I** inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.

HY-N11913

Siderin	Structural Classification Source classification Coumarins Toona ciliata Roem. Phenylpropanoids Plants Meliaceae	Biochemical Assay Reagents
Siderin is a Photosystem II inhibitor that effectively inhibits ATP synthesis and chloroplast electron transport during photosynthesis in isolated spinach. Siderin can be used in the study of plant photosynthesis .

HY-N10094

Maculosidine	Structural Classification Alkaloids Source classification Rutaceae Quinoline Alkaloids Plants Balfourodendron riedelianum (Engl.) Engl.	Others
Maculosidine is a furoquinoline alkaloid that can be isolated from Balfourodendron riedelianum. Maculosidine inhibits ATP synthesis, basal, phosphorylating and uncoupled electron transport in plants. Maculosidine inhibits Hill reaction on spinach chloroplasts .

HY-130055R

HQNO (Standard)	Structural Classification Natural Products Microorganisms Source classification	Mitochondrial Metabolism
HQNO (Standard) is the analytical standard of HQNO. This product is intended for research and analytical applications. HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2].

HY-101415R

Coenzyme Q9 (Standard) Ubiquinone Q9 (Standard); CoQ9 (Standard); Ubiquinone 9 (Standard)	Quinones Structural Classification Microorganisms Source classification Benzene Quinones Endogenous metabolite	Reference Standards Apoptosis Endogenous Metabolite
Coenzyme Q9 (Standard) is the analytical standard of Coenzyme Q9. This product is intended for research and analytical applications. Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .

HY-N0111R

Coenzyme Q10 (Standard)	Quinones Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Benzene Quinones Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species Ferroptosis
Coenzyme Q10 (Standard) is the analytical standard of Coenzyme Q10. This product is intended for research and analytical applications. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1756R

Rotenone (Standard)	Structural Classification Flavonoids Leguminosae Derris trifoliata Lour. Plants	Mitochondrial Metabolism Autophagy Apoptosis
Rotenone (Standard) is the analytical standard of Rotenone. This product is intended for research and analytical applications. Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.

HY-N9610

Coenzyme Q6 Ubiquinone 30	Quinones Structural Classification Microorganisms Source classification Benzene Quinones	Endogenous Metabolite
Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage .

HY-N1839

3-Hydroxybakuchiol	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Otholobium mexicanum (L.f.) J.W.Grimes	Apoptosis Glycosidase
3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC₅₀: 345 μM) .

HY-N12887

Mycothiazole	Structural Classification Natural Products Marine natural products Source classification Sponge	Mitochondrial Metabolism
Mycothiazole is an inhibitor for mitochondrial electron transport chain (ETC) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 (IC₅₀ is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans .

HY-114936

Piericidin A 3 Publications Verification AR-054	Structural Classification Neurological Disease Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Disease Research Fields	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-N0354

Anthraquinone	Seeds of Cassia tora Linn. Quinones Structural Classification other families Classification of Application Fields Leguminosae Anthraquinones Source classification Other Diseases Plants Disease Research Fields	Virus Protease Topoisomerase Apoptosis
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis .

HY-N6715

Tenuazonic acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Biological Pesticide Research Agricultural Research	Influenza Virus Bacterial Enterovirus Photosystem II
Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD₅₀ is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a *photosystem II (PSII)* inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .

HY-N6715R

Tenuazonic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Influenza Virus Bacterial Enterovirus Photosystem II
Tenuazonic acid (Standard) is the analytical standard of Tenuazonic acid. This product is intended for research and analytical applications. Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD₅₀ is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a *photosystem II (PSII)* inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .

Cat. No.	Product Name	Chemical Structure

HY-N0111S2

Coenzyme Q10-d9
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B1849S

Hexazinone-d6
Hexazinone-d₆ is the deuterium labeled Hexazinone . Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis .

HY-136406S

Bongkrekic acid-13C28

Bongkrekic acid- ¹³C₂₈ is the ¹³C labeled Bongkrekic acid (HY-136406). Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .

HY-W653921

Tenuazonic acid-d13

Tenuazonic acid-d₁₃ is deuterium labeled Tenuazonic acid. Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD₅₀ is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .

HY-N0111S

Coenzyme Q10-d6
Coenzyme Q10-d₆ is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B0817S

Pyridaben-d13

Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-N6715S

Tenuazonic acid-13C10

Tenuazonic acid- ¹³C₁₀ is ¹³C labeled Tenuazonic acid (HY-N6715). Tenuazonic acid is a nonhost-selective mycotoxin belonging to the tetramic acids family. Tenuazonic acid inhibits protein biosynthesis on ribosomes by suppressing the release of new protein. Tenuazonic acid is acutely toxic, and oral LD50 is set between 81-186 mg/kg in rats and mice. Tenuazonic acid blocks electron transport beyond the primary quinone receptor (QA) by interacting with the D1 protein and is a photosystem II (PSII) inhibitor. In addition, Tenuazonic acid has antiviral effects on measles virus, enterovirus, respiratory virus and so on. Tenuazonic acid has an inhibitory effect on skin cancer .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks