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dual FXR/PPARδ agonist-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175516
    dual FXR/PPARδ agonist-2

    		FXR PPAR Inflammation/Immunology
    dual FXR/PPARδ agonist-2 is a FXR/PPARδ dual agonist through hybridation of FXR agonist GW-4064 and PPARδ agonist GW-0742.dual FXR/PPARδ agonist-2 displays potent dual-target activities with a FXR agonistic EC50 of 12.28 nM and 69 % PPARδ activation at 100 nM. dual FXR/PPARδ agonist-2 shows anti-fibrotic effects in pulmonary fibrosis mouse model .
    dual FXR/PPARδ agonist-2

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