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Results for "

diazo

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

7

Fluorescent Dye

2

Biochemical Assay Reagents

2

Peptides

2

Natural
Products

2

Isotope-Labeled Compounds

6

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-140925
    Diazo Biotin-PEG3-alkyne

    		PROTAC Linkers Cancer
    Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Diazo Biotin-PEG3-alkyne
  • HY-140918
    Diazo Biotin-PEG3-azide

    		PROTAC Linkers Cancer
    Diazo Biotin-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Diazo Biotin-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Diazo Biotin-PEG3-azide
  • HY-108357
    6-Diazo-5-oxo-L-nor-Leucine
    10+ Cited Publications

    L-6-diazo-5-oxonorleucine; DON

    		 Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
    6-Diazo-5-oxo-L-nor-Leucine
  • HY-W048205
    N6-Diazo-L-Fmoc-lysine

    		Amino Acid Derivatives Others
    N6-Diazo-L-Fmoc-lysine is an active compand and can be used in a variety of chemical studies. N6-Diazo-L-Fmoc-lysine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    N6-Diazo-L-Fmoc-lysine
  • HY-140930
    Diazo Biotin-PEG3-DBCO

    		ADC Linker Cancer
    Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Diazo Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    Diazo Biotin-PEG3-DBCO
  • HY-177516
    5-Diazo-4-oxonorvaline

    		Others Others
    5-Diazo-4-oxonorvaline is a type of asparagine analogue, belonging to diazo compounds. 5-Diazo-4-oxonorvaline can specifically target the active site of glycosyl asparaginase (Ki = 80 μM) .
    5-Diazo-4-oxonorvaline
  • HY-108357R
    6-Diazo-5-oxo-L-nor-Leucine (Standard)

    L-6-diazo-5-oxonorleucine (Standard); DON (Standard)

    		 Reference Standards Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-W142025
    6-Diazo-5-oxo-D-norleucine

    		Amino Acid Derivatives γ-Glutamyl Transferase (GGT) Metabolic Disease
    6-Diazo-5-oxo-D-norleucine, a D-Glutamine (HY-100587) analog, is a γ-glutamyl transferase inhibitor .
    6-Diazo-5-oxo-D-norleucine
  • HY-136078
    Tetrazine-diazo-PEG4-biotin

    		ADC Linker Cancer
    Tetrazine-diazo-PEG4-biotin is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Tetrazine-diazo-PEG4-biotin is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Tetrazine-diazo-PEG4-biotin
  • HY-N14906
    4-Diazo-3-methoxy-2,5-cyclohexadien-1-one

    		Bacterial Infection
    4-Diazo-3-methoxy-2,5-cyclohexadien-1-one has favourable anti-anaerobe activity. MIC: 0.4 μg/mL for Clostridium and Bacterioids, 0.2 μg/mL for Haemophilus .
    4-Diazo-3-methoxy-2,5-cyclohexadien-1-one
  • HY-D0334
    Direct Red 81

    		Fluorescent Dye
    Direct Red 81 is a diazo dye with a very high water solubility. The dye adsorption efficiency of Direct Red 81 is increased by increasing the adsorbent dose and adsorption time .
    Direct Red 81
  • HY-125058
    Kinamycin C

    		Apoptosis Cancer
    Kinamycin C is a bacterial metabolite containing a diazo group with anticancer activities. Kinamycin C induces a rapid apoptotic response in K562 cells .
    Kinamycin C
  • HY-D0213
    Sudan Black B

    		Fluorescent Dye Others
    Sudan Black B, a fat-soluble diazo dye, is a histochemical stain. Sudan Black B can be used for staining of neutral triglycerides and lipids .
    Sudan Black B
  • HY-D0468
    Basic Brown 1

    		Fluorescent Dye Others
    Basic Brown 1 is a diazo dyes .
    Basic Brown 1
  • HY-153151
    Fmoc-DON-Boc

    		Drug Intermediate Cancer
    Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist .
    Fmoc-DON-Boc
  • HY-128775
    JHU395

    		Drug Derivative Cancer
    JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST .
    JHU395
  • HY-122218
    JHU-083
    5+ Cited Publications

    		 Glutaminase Neurological Disease
    JHU-083, a proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357), is an orally active and selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b + cells and experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals .
    JHU-083
  • HY-W423183
    2-(Morpholin-4-yl)ethane-1-sulfonamide

    		Drug Derivative Cancer
    2-(Morpholin-4-yl)ethane-1-sulfonamide is a byproduct in the synthesis of diazo compounds.
    2-(Morpholin-4-yl)ethane-1-sulfonamide
  • HY-D0024
    Sudan I

    Solvent Yellow 14

    		 Bacterial Others
    Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .
    Sudan I
  • HY-W328317
    Fast garnet GBC sulfate salt, 90%

    Azoic diazo No. 4, 90%

    		 Biochemical Assay Reagents Others
    Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.
    Fast garnet GBC sulfate salt, 90%
  • HY-W019776
    Sudan I-d5

    Solvent Yellow 14-d5

    		 Bacterial Infection
    Sudan I-d5 is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .
    Sudan I-d5
  • HY-W110888
    Brilliant Yellow

    		GLUT Neurological Disease
    Brilliant Yellow, a diazo-containing sulfonic aci, is also a potent VGLUT-specific inhibitor. Brilliant Yellow is membrane-impermeable. However, there are some Brilliant Yellow analogs with low cytotoxicity and cell penetration. Brilliant Yellow analogs work on glutamatergic transmission in hippocampal neurons .
    Brilliant Yellow
  • HY-D0024R
    Sudan I (Standard)

    Solvent Yellow 14 (Standard)

    		 Reference Standards Bacterial Others
    Sudan I (Standard) is the analytical standard of Sudan I. This product is intended for research and analytical applications. Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .
    Sudan I (Standard)
  • HY-D1506
    Fl-DIBO

    		Fluorescent Dye Others
    Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fl-DIBO
  • HY-D0932
    Sudan IV

    Solvent Red 24; C.I. 26105

    		 Biochemical Assay Reagents Aryl Hydrocarbon Receptor Cytochrome P450 Metabolic Disease
    Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .
    Sudan IV
  • HY-D0932R
    Sudan IV (Standard)

    Solvent Red 24 (Standard); C.I. 26105 (Standard)

    		 Biochemical Assay Reagents Aryl Hydrocarbon Receptor Cytochrome P450 Metabolic Disease
    Sudan IV (Standard) (Solvent Red 24 (Standard)) is the analytical standard of Sudan IV (HY-D0932). This product is intended for research and analytical applications. Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.
    Sudan IV (Standard)
  • HY-D0932S
    Sudan IV-d6

    Solvent Red 24-d6; C.I. 26105-d6

    		 Isotope-Labeled Compounds Biochemical Assay Reagents Aryl Hydrocarbon Receptor Cytochrome P450 Metabolic Disease
    Sudan IV-d6 (Solvent Red 24-d6) is the deuterium labeled Sudan IV(HY-D0932). Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .
    Sudan IV-d6

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