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Results for "

desmethyl analogue

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123833
    PF-05661014

    		Sodium Channel Others
    PF-05661014, a desmethyl analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing inactivated channels via interaction with D4 VSD. PF-05661014 can be used for research of sodium channel modulation .
    PF-05661014
  • HY-152795
    N4-Desmethyl wyosine

    		Nucleoside Antimetabolite/Analog Others
    N4-Desmethyl wyosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    N4-Desmethyl wyosine
  • HY-111160
    SKF 83509

    		Dopamine Receptor Neurological Disease
    SKF 83509, a desmethyl analogue of SCH 23390 (HY-19545A), is a selective dopamine D1 antagonist with a Ki of 70.2 nM. SKF 83509 has no activity at dopamine D2 receptors .
    SKF 83509
  • HY-169450
    (-)-9-Hydroxycorynantheidine

    9-O-desmethyl mitragynine

    		 Opioid Receptor Neurological Disease
    (-)-9-Hydroxycorynantheidine (9-O-Desmethyl mitragynine), the 9-demethyl analogue of Mitragynine, is a selective and partial agonist of μ-opioid receptor. (-)-9-Hydroxycorynantheidine inhibits electrically stimulated twitch contraction in guinea-pig ileum .
    (-)-9-Hydroxycorynantheidine
  • HY-152797
    N4-Desmethyl-N5-Methyl wyosine

    		Nucleoside Antimetabolite/Analog Others
    N4-Desmethyl-N5-Methyl wyosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) .
    N4-Desmethyl-N5-Methyl wyosine

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