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Results for "

derivatization

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Amino Acid Derivatives (2) Bcl-2 Family (2) Biochemical Assay Reagents (47) Drug Metabolite (2) Endogenous Metabolite (1) Fluorescent Dye (7) Fungal (1) HIV (1) Insulin Receptor (2) Ligands for E3 Ligase (7)
By Research Areas:	Cancer (11) Endocrinology (2) Infection (1) Metabolic Disease (2)
Click Chemistry:	TCO (2) Labeling and Fluorescence Imaging (2) Azide (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136590

2-Nitrosopyridine 1 Publications Verification	Biochemical Assay Reagents	Others
2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .

HY-W454678

5-Bromomethylthalidomide	Ligands for E3 Ligase	Cancer
5-Bromomethylthalidomide is an E3 ligase activator which may be further derivatized by substitution at bromide.

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dye	Others
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-137025

(S)-NIFE	Amino Acid Derivatives	Others
(S)-NIFE is a chiral derivatizing agent for proteinogenic amino acid analysis .

HY-D0035

MPAC-Br	Fluorescent Dye	Others
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-147232

N-Acryloyl-1-pyrenebutylamine	Fluorescent Dye	Others
N-Acryloyl-1-pyrenebutylamine is a potent fluorescent derivatization agent. N-Acryloyl-1-pyrenebutylamine combines with an alkyl-acrylamide side-chain to give fluorescence function on the polymer. .

HY-118469

Phanquinone 11925 C; Entronon	Biochemical Assay Reagents	Others
Phanquone (11925 C; Entronon) derives from a hydride of a 4,7-phenanthroline. Phanquone is applied as an original precolumn derivatization reagent for amino acids .

HY-138064

4-APC hydrobromide	Biochemical Assay Reagents	Others
4-APC hydrobromide is a highly sensitive and selective derivatization agent for aldehydes. 4-APC hydrobromide possesses an aniline moiety for a fast selective reaction with aliphatic aldehydes as well as a quaternary ammonium group for improved MS sensitivity. 4-APC hydrobromide allows highly sensitive and selective MS detection of aldehydes .

HY-131125

trans-4-Nitrocinnamoyl chloride	Biochemical Assay Reagents	Others
trans-4-Nitrocinnamoyl chloride is used as derivatization reagent .

HY-W425671

N-Isobutyryl-L-cysteine	Biochemical Assay Reagents Endogenous Metabolite	Others
N-Isobutyryl-L-cysteine serves as a chiral derivatizing agent that is extensively utilized for the separation of amino acid enantiomers.

HY-156559

GlcNAc-SH	Biochemical Assay Reagents	Others
GlcNAc-SH is a thiol-derivatized saccharide that can be used to label Dha to generate glycoprotein mimics .

HY-W800822

Lactic acid dodecyl ester Lauryl lactate	Biochemical Assay Reagents	Others
Lactic acid dodecyl ester (Lauryl lactate) is a lipid with a terminal hydroxyl group at the head. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W250446

(R)-Methyl 3-hydroxydecanoate	Biochemical Assay Reagents	Others
(R)-Methyl 3-hydroxydecanoate is an enantiomerically pure hydroxylated fatty acid methyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Fluorescent Dye	Others
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-W576868

Thalidomide-4,5-F	Ligands for E3 Ligase	Cancer
Thalidomide-4,5-F is a fluorinated Thalidomide analogue. Thalidomide promotes the ubiquitinylation of proteins. The structure may be further derivatized via substitution at its fluorines.

HY-W614135

7-Methyl-8-oxononanoic acid	Biochemical Assay Reagents	Others
7-Methyl-8-oxononanoic acid is an intermediate for synthesis of conjugated molecules. The acid group can derivatize amine-containing molecules in the presence of activators such as EDC or HATU.

HY-W742484

1-Linoleoyl-(2S)-glycerol	Biochemical Assay Reagents	Others
1-Linoleoyl-(2S)-glycerol is a lipid with a structure similar to that of linoleic acid. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-172295

Tetrafluoro-thalidomide	Ligands for E3 Ligase	Cancer
Tetrafluoro-thalidomide is a fluorinated Thalidomide analogue. Tetrafluoro-thalidomide is an activator of E3 ligase, which ubiquitinylates proteins for later proteolysis. The structure may be further derivatized via substitution at its fluorines.

HY-W413662

4-((4-Methoxybenzyl)oxy)butan-1-ol	Biochemical Assay Reagents	Others
4-[(4-Methoxyphenyl)methoxy]butan-1-ol is a compound with a methyl phenol group and a butanol tail. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W800816

1,2-Di-O-tetradecyl-rac-glycerol	Biochemical Assay Reagents	Others
1,2-Di-O-tetradecyl-rac-glycerol is a hydrophobic compound that has been found to occure naturally in the body. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W586821

Thalidomide-1-Me-5-NH2	Ligands for E3 Ligase	Cancer
Thalidomide-1-Me-5-NH2 is an aminated Thalidomide analogue. E3 Ligase activators such as this may be used in the design of PROTAC molecules via derivatization at its amine.

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-161071

Antioxidant/anticancer agent 1	Fungal	Infection Cancer
Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1 .

HY-D1730

AF488 NHS ester 1 Publications Verification	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-W453715

Thalidomide-4-F,5-Br	Ligands for E3 Ligase	Cancer
Thalidomide-4-F,5-Br is a Thalidomide analogue. Thalidomide recruits E3 ligase for the ubiquitinylation and subsequent proteolysis of a target protein. This molecule may be derivatized through substitution at fluorine or bromine.

HY-W837135

5-Hydrazinyl thalidomide hydrochloride	Ligands for E3 Ligase	Cancer
5-Hydrazinyl thalidomide hydrochloride is a Thalidomide analogue featuring a hydrazine. PROTAC linkers are made to recruit E3 ligase for the ubiquitinylation of target proteins. The hydrazine may be used for further derivatization via reactions with various carbonyl groups.

HY-W800842

1-Ethylnonyl 8-bromooctanoate	Biochemical Assay Reagents	Others
1-Ethylnonyl 8-bromooctanoate is a lipid featuring a bromide along an octanoate chain linking to a C11 chain. 1-Ethylnonyl 8-bromooctanoate can be derivatized via substitution at the bromide leaving group.

HY-W014815

BPBA 2-Bromopyridine-5-boronic acid	Biochemical Assay Reagents	Others
BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent. BPBA is used to derivatize brassinosteroids (BRs). BPBA is used for biomarker analysis of exposure to environmental pollutants such as styrene and 1,3-butadiene .

HY-W190921

t-Butyl 3-(hydroxypropoxyl)-propanoate	Biochemical Assay Reagents	Others
t-Butyl 3-(hydroxypropoxyl)-propanoate contains reactive hydroxyl and t-butyl protected carboxyl moieties. The hydroxyl group can react to further derivatize the compound. The t-butyl carbonyl group can be deprotected under acidic conditions.

HY-W016455

6-Bromo-1-hexanol	Biochemical Assay Reagents	Others
6-Bromo-1-hexanol posesses a terminal bromine and hydroxylic group. The bromine is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dye	Others
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

HY-134106

N-Boc-erythro-sphingosine	Biochemical Assay Reagents	Others
N-Boc-erythro-sphingosine is composed of t-butyl ester protected N-acetylsphingosine with a fatty acid tail. The hydroxy group enables further derivatization or replacement with other reactive functional groups. The t-butyl group can be deprotected under mild acidic conditions.

HY-W174661

tert-Butyl 6-hydroxyhexanoate	Biochemical Assay Reagents	Others
tert-Butyl 6-hydroxyhexanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

HY-W460072

tert-Butyl 7-hydroxyheptanoate	Biochemical Assay Reagents	Others
tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

HY-W591335

Biotin-PEG5-OH Biotin-PEG5-alcohol	Biochemical Assay Reagents	Others
Biotin-PEG5-OH (Biotin-PEG5-alcohol) is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.

HY-W591992

PEG17	Biochemical Assay Reagents	Others
PEG17 is a polymer consisiting of repeating ethylene glycol subunits and terminal hydroxyl groups. The ethylene glycol units increase the water solubility of hydrophobic compounds, allowing for them to be more compatible in aqueous settings. The terminal hydroxyl groups can react to further derivatize the compound.

HY-W591972

6-Hydroxyhexyl 4-methylbenzenesulfonate	Biochemical Assay Reagents	Others
6-Hydroxyhexyl 4-methylbenzenesulfonate is a six carbon linker containing a hydroxyl group and a tosyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-W190911

Cyclooct-4-en-1-yl(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate	Biochemical Assay Reagents	Others
Cyclooct-4-en-1-yl(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate is commonly used in Click Chemistry reactions. The hydroxyl group allows for additional reactions to take place to further derivatize the compound.

HY-W190939

C11-PEG9-alcohol	Biochemical Assay Reagents	Others
C11-PEG9-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W800616

C11-PEG4-alcohol	Biochemical Assay Reagents	Others
C11-PEG4-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W012971

5-Amino-1-pentanol	Biochemical Assay Reagents	Others
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-149872

DCA-RMR1	Biochemical Assay Reagents	Others
DCA-RMR1 is a cross-linker. DCA-RMR1 elicits facile bicyclization of native peptides via N-terminus Cys-Cys cross-linking. DCA-RMR1 derivatizes RMR1 with 1,3-dichloroacetone (DCA) .

HY-W586320

Thalidomide-5-Br,6-F	Ligands for E3 Ligase	Cancer
Thalidomide-5-Br,6-F is a Thalidomide analogue. Thalidomide-5-Br,6-F is an activator of E3 ligase, which ubiquitinylates proteins for proteolysis. The structure may be further derivatized via substitution at fluorine or bromine.

HY-W591308

3-[2-(3-Hydroxypropoxy)ethoxy]propan-1-ol	Biochemical Assay Reagents	Others
3-[2-(3-hydroxypropoxy)ethoxy]propan-1-ol is a linker consisting of two terminal hydroxyl groups. The partial PEG chain increases the water solubility of a compound in aqueous media. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.

HY-W440891

DSPE-PEG-OH (MW 1000)	Biochemical Assay Reagents	Others
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.

HY-W702728

rac 1-Palmitoyl-2-chloropropanediol	Biochemical Assay Reagents	Others
rac 1-Palmitoyl-2-chloropropanediol is a monoacylglycerol of palmitic acid at the sn-1 position and a chloride group at the sn-2 position. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The chlorine is a good leaving group and can undergo substitution reactions.

Cat. No.	Product Name	Type

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Protein Labeling
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dyes/Probes
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

HY-D1730A

AF488 NHS ester TEA 1 Publications Verification	Fluorescent Dyes/Probes
AF488 NHS ester TEA is an amine specific fluorescence probe (λ_em=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dyes/Probes
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-D0035

MPAC-Br	Fluorescent Dyes/Probes
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-W591335

Biotin-PEG5-OH Biotin-PEG5-alcohol	Fluorescent Dyes/Probes
Biotin-PEG5-OH (Biotin-PEG5-alcohol) is a biotinylation reagent containing a primary hydroxyl that can be derivatized. The PEG spacer provides greater solubility to labeled molecules compared to reagents having only hydrocarbon spacers.

Cat. No.	Product Name	Type

HY-W074541

Girard’s reagent T

Trimethylacetohydrazideammonium chloride

Surfactants

Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

HY-W440891

DSPE-PEG-OH (MW 1000)	Drug Delivery
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.

Cat. No.	Product Name	Target	Research Area

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

Cat. No.	Product Name		Classification

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH		TCO Labeling and Fluorescence Imaging
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride		Labeling and Fluorescence Imaging TCO
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-W800664

5-(Azido-PEG4)-pent-2-yn-1-ol		Azide
5-(Azido-PEG4)-pent-2-yn-1-Ol is a PEG linker containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

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