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dTAGV-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145514C
    dTAGV-1 hydrochloride
    1 Publications Verification

    		 FKBP PROTACs Cancer
    dTAGV-1 hydrochloride is a potent and selective degrader of FKBP12 F36V-tagged proteins PROTAC degrader. dTAGV-1 hydrochloride can induce degradation of FKBP12 F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A)) [1].
    dTAGV-1 hydrochloride
  • HY-145514
    dTAGV-1 TFA
    1 Publications Verification

    		 PROTACs FKBP Cancer
    dTAGV-1 TFA is a potent and selective degrader of FKBP12 F36V-tagged proteins PROTAC degrader. dTAGV-1 TFA can induce degradation of FKBP12 F36V-Nluc in vivo. (Pink: Target Protein Ligand (HY-114420); Black: Linker (HY-W012001); Blue: VHL Ligand (HY-112078); VHL Ligan+Linker (HY-173628A)) [1]
    dTAGV-1 TFA
  • HY-145514A
    dTAGV-1-NEG

    		PROTACs FKBP Cancer
    dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12 F36V-selective degrader [1].
    dTAGV-1-NEG
  • HY-145514B
    dTAGV-1-NEG TFA

    		PROTACs FKBP Cancer
    dTAGV-1-NEG TFA is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1-NEG TFA is an FKBP12 F36V-selective degrader [1].
    dTAGV-1-NEG TFA
  • HY-173628A
    (S,R,S)-AHPC-Me-N-Boc-7-aminoheptanoic acid

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-Me-N-Boc-7-aminoheptanoic acid is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTAC dTAGV-1 TFA (HY-145514) [1].
    (S,R,S)-AHPC-Me-N-Boc-7-aminoheptanoic acid
  • HY-173627
    (R,S,S)-VH032-Me

    		Ligands for E3 Ligase Cancer
    (R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase. (R,S,S)-VH032-Me can be connected to the ligand for protein by a linker to form dTAGV-1-NEG (HY-145514A). PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1].
    (R,S,S)-VH032-Me
  • HY-173628
    (R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid is a E3 Ligase Ligand-Linker Conjugate, consisting of N-Boc-7-aminoheptanoic acid (HY-W012001) and the corresponding Linker. (R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid can be used for the synthesis of dTAGV-1-NEG (HY-145514A) [1].
    (R,S,S)-VH032-Me-N-Boc-7-aminoheptanoic acid

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