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Results for "

concanavalin A

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

20

Biochemical Assay Reagents

2

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1

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3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2149
    Concanavalin A
    5 Publications Verification

    		 Antibiotic Apoptosis Infection Inflammation/Immunology Cancer
    Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury .
    Concanavalin A
  • HY-P2149A
    Concanavalin A (agarose)

    		Biochemical Assay Reagents Others
    Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .
    Concanavalin A (agarose)
  • HY-NP164
    Concanavalin A-HRP

    Con A-HRP

    		 Fluorescent Dye Cancer
    Concanavalin A-HRP (Con A-HRP) is a HRP-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-HRP
  • HY-NP164B
    Concanavalin A-AF488

    Con A-AF488

    		 Fluorescent Dye Cancer
    Concanavalin A-AF488 (Con A-AF488) is an AF488-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF488
  • HY-NP164K
    Concanavalin A-AF568

    Con A-AF568

    		 Fluorescent Dye Cancer
    Concanavalin A-AF568 (Con A-AF546) is an AF568-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF568
  • HY-NP164M
    Concanavalin A-AF680

    Con A-AF680

    		 Fluorescent Dye Cancer
    Concanavalin A-AF680 (Con A-AF680) is an AF680-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF680
  • HY-NP164J
    Concanavalin A-AF555

    Con A-AF555

    		 Fluorescent Dye Cancer
    Concanavalin A-AF555 (Con A-AF555) is an AF555-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF555
  • HY-NP164C
    Concanavalin A-AF350

    Con A-AF350

    		 Fluorescent Dye Cancer
    Concanavalin A-AF350 (Con A-AF350) is an AF350-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF350
  • HY-NP164L
    Concanavalin A-AF647

    Con A-AF647

    		 Fluorescent Dye Cancer
    Concanavalin A-AF647 (Con A-AF647) is an AF647-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF647
  • HY-NP164H
    Concanavalin A-AF532

    Con A-AF532

    		 Fluorescent Dye Cancer
    Concanavalin A-AF532 (Con A-AF532) is an AF532-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF532
  • HY-NP164D
    Concanavalin A-AF405

    Con A-AF405

    		 Fluorescent Dye Cancer
    Concanavalin A-AF405 (Con A-AF405) is an AF405-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF405
  • HY-NP164I
    Concanavalin A-AF546

    Con A-AF546

    		 Fluorescent Dye Cancer
    Concanavalin A-AF546 (Con A-AF546) is an AF546-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF546
  • HY-NP164E
    Concanavalin A-AF430

    Con A-AF430

    		 Fluorescent Dye Cancer
    Concanavalin A-AF430 (Con A-AF430) is an AF430-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-AF430
  • HY-NP0153
    Concanavalin A (Rhodamine)

    Con A (Rhodamine)

    		 Fluorescent Dye Others
    Concanavalin A (Con A) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Concanavalin A (Con A) Rhodamine is a biological material or organic compound that can be used in life science research .
    Concanavalin A (Rhodamine)
  • HY-NP164N
    Concanavalin A-Cy3

    Con A-Cy3

    		 Fluorescent Dye Cancer
    Concanavalin A-Cy3 (Con A-Cy3) is a Cy5 (HY-D0822)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins (Ex/Em = 554/568 nm) .
    Concanavalin A-Cy3
  • HY-NP164O
    Concanavalin A-Cy5

    Con A-Cy5

    		 Fluorescent Dye Cancer
    Concanavalin A-Cy5 (Con A-Cy5) is a Cy5 (HY-D0821)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins (Ex/Em = 630/670 nm) .
    Concanavalin A-Cy5
  • HY-NP164A
    Concanavalin A-Cy5.5

    Con A-Cy5.5

    		 Fluorescent Dye Cancer
    Concanavalin A-Cy5.5 (Con A-Cy5.5) is a Cy5.5 (HY-D0924)-labled Concanavalin A (HY-P2149). Concanavalin A is a Ca 2+/Mn 2+-dependent and mannose/glucose-binding plant lectin. Concanavalin A binds the N- and O-glycosylated proteins of head and neck carcinoma cells glycoproteins .
    Concanavalin A-Cy5.5
  • HY-W340234
    4,5-Dibromo-2-pyrrolic acid

    		Galectin Others
    4,5-Dibromo-2-pyrrolic acid (compound 2) is an immunosuppressive compound. 4,5-Dibromo-2-pyrrolic acid suppresses the proliferative response of splenocytes to suboptimal concentrations of the mitogen, concanavalin A (Con A) .
    4,5-Dibromo-2-pyrrolic acid
  • HY-P3107
    Homodestcardin

    		Endogenous Metabolite Inflammation/Immunology
    Homodestcardin, a destruxinbased cyclodepsipeptide, is a immunosuppressant. Homodestcardin, a fungal metabolite, displays pronounced activities against concanavalin A (Con A) activation, with an IC50 value of 0.86 μM .
    Homodestcardin
  • HY-11011
    A-770041
    5+ Cited Publications

    		 Src Inflammation/Immunology
    A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection .
    A-770041
  • HY-16384
    L-156602

    Antibiotic L 156602; PD 124966

    		 Complement System Inflammation/Immunology
    L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH) .
    L-156602
  • HY-P1997
    Ferrichrome Iron-free

    Desferrichrome; DFC; N-Desferriferrichrome

    		 Biochemical Assay Reagents Others
    Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
    Ferrichrome Iron-free
  • HY-135766
    Colletodiol

    (+)-Colletodiol

    		 Influenza Virus Infection
    Colletodiol is a fungal metabolite that has been found in D. grovesii and has immunosuppressant and antiviral activities. It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s=12 and 5 μg/mL, respectively).1 Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.
    Colletodiol
  • HY-130757
    Remisporine B

    		Endogenous Metabolite Inflammation/Immunology
    Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC50 of 30.1 µg/mL and 32.4 µg/mL .
    Remisporine B
  • HY-120600
    Sibiriline

    		Necroptosis Apoptosis RIP kinase Inflammation/Immunology
    Sibiriline is a specific competitive inhibitor of RIPK1 that targets the RIPK1 ATP-binding site and locks it in an inactive conformation. Sibiriline inhibits TNF-induced RIPK1-dependent necroptosis and RIPK1-dependent apoptosis, but does not protect cells from caspase-dependent apoptosis. Sibiriline protects mice from concanavalin A-induced hepatitis and has the potential to inhibit immune-dependent hepatitis. .
    Sibiriline
  • HY-137822
    p-Nitrophenyl α-D-mannopyranoside

    4-Nitrophenyl a-D-mannopyranoside

    		 Glycosidase Others
    p-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149)) .
    p-Nitrophenyl α-D-mannopyranoside
  • HY-170362
    cGAS-IN-4

    		Cyclic GMP-AMP Synthase Inflammation/Immunology
    cGAS-IN-4 (Compound 36) is an orally active inhibitor for cyclic GMP-AMP synthase (cGAS) with IC50 of 32 nM and 5.8 nM for h-cGAS and m-cGAS. cGAS-IN-4 inhibits the cGAMP in THP-1 cell with an IC50 of 60 nM, which improves the cellular potency. cGAS-IN-4 exhibits anti-inflammatory efficacy in Concanavalin A (HY-P2149)-induced acute liver injury in mouse models . orally active, THP-1, C57Bl/6 mouse, orally active
    cGAS-IN-4
  • HY-175869
    Ferroptosis-IN-22

    		Ferroptosis Metabolic Disease Inflammation/Immunology
    Ferroptosis-IN-22 is a selective ferroptosis inhibitor by targeting NCOA4 and disrupting its interaction with ferritin with an EC50 of 520 nM and a Kd of 0.78 μM. Ferroptosis-IN-22 has a strong inhibitory activity against ferroptosis induced by multiple ferroptosis inducers (RSL3 (HY-100218A), Erastin (HY-15763), ML210 (HY-100003), FIN56 (HY-103087)), but does not inhibit necrosis induced by H2O2 or apoptosis induced by STS (HY-15141). Ferroptosis-IN-22 effectively ameliorates Concanavalin A (HY-P2149)-induced acute liver injury. Ferroptosis-IN-22 can be used for the study of ferroptosis-related diseases .
    Ferroptosis-IN-22

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