Search Result
Results for "
cationic liposome
" in MedChemExpress (MCE) Product Catalog:
14
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-112005
-
DOPE
5 Publications Verification
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Liposome
Endogenous Metabolite
|
Inflammation/Immunology
|
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
-
- HY-144018
-
|
Liposome
|
Others
|
18:1 EPC chloride is a cationic alkylated phospholipid and also an egg yolk phosphatidylcholine. 18:1 EPC chloride can be used in research on liposomes and drug delivery .
|
-
-
- HY-130751
-
DODAP
1 Publications Verification
|
Liposome
|
Inflammation/Immunology
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
-
-
- HY-144021
-
|
Liposome
|
Others
|
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
|
-
-
- HY-144025
-
|
Liposome
|
Others
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
-
- HY-112005GL
-
Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
|
Liposome
|
Inflammation/Immunology
|
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
-
- HY-160275
-
|
Liposome
|
Others
|
DOPE-PEG-Fluor 555,MW 2000 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
-
- HY-168777
-
|
Liposome
|
Others
|
Lipid 7-1 is an ionizable cationic lipid that can be used for the preparation of liposomes .
|
-
-
- HY-145797
-
|
Liposome
|
Others
|
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
|
-
-
- HY-144023
-
|
Liposome
|
Others
|
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
|
-
-
- HY-W800782
-
|
Liposome
|
Others
|
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .
|
-
-
- HY-139298
-
L319
1 Publications Verification
Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
|
Liposome
|
Inflammation/Immunology
|
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
|
-
-
- HY-112763
-
|
Liposome
|
Inflammation/Immunology
|
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
|
-
-
- HY-139200
-
DOTMA
1 Publications Verification
|
Liposome
|
Others
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
-
- HY-153125
-
|
Liposome
|
Others
|
DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids .
|
-
-
- HY-W800783
-
CDESA
|
Liposome
|
Others
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
-
-
- HY-W590549
-
DODAC
|
Liposome
|
Others
|
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .
|
-
-
- HY-W800776
-
1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide
|
Liposome
|
Others
|
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
|
-
-
- HY-112766
-
|
Liposome
|
Others
|
DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
|
-
-
- HY-142997
-
|
Liposome
|
Others
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
-
- HY-160581
-
|
Liposome
|
Others
|
OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
|
-
-
- HY-172558
-
|
Biochemical Assay Reagents
|
Others
|
MEL-A is a glycolipid biosurfactant. MEL-A can be produced from vegetable oils by Pseudozyma yeasts. MEL-A can improve the low-temperature fluidity of biodiesel and hydrocarbon fuels. MEL-A is composed of a mixture of MEL-A isoforms with variable lengths of the fatty acid chain. MEL-A can significantly increases gene transfection by cationic liposomes via membrane fusion .
|
-
-
- HY-W416291
-
Poly(A)
|
Biochemical Assay Reagents
|
Cancer
|
Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.
|
-
-
- HY-P10968
-
|
Bacterial
Antibiotic
|
Infection
|
KT2 is a cationic amphipathic antibacterial peptide. KT2 can completely kill cells of E. coli O157:H7. KT2 has potent anti-biofilm activity and prevents biofilm formation of E. coli O157:H7. KT2 significantly binds to bacterial surface LPS and interacts with the lipids of liposomes with great penetration capability into bacterial cells, followed by bond to DNA and other cytoplasmic membrane .
|
-
-
- HY-131119
-
Dioctadecyldimethylammonium bromide; DODAB
|
Liposome
|
Others
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-112005GL
-
Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
|
Fluorescent Dye
|
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
Cat. No. |
Product Name |
Type |
-
- HY-112005
-
DOPE
5 Publications Verification
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Drug Delivery
|
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-144018
-
|
Drug Delivery
|
18:1 EPC chloride is a cationic alkylated phospholipid and also an egg yolk phosphatidylcholine. 18:1 EPC chloride can be used in research on liposomes and drug delivery .
|
-
- HY-130751
-
DODAP
1 Publications Verification
|
Drug Delivery
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
-
- HY-144021
-
|
Drug Delivery
|
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
|
-
- HY-144025
-
|
Drug Delivery
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
- HY-139298
-
L319
1 Publications Verification
Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
|
Drug Delivery
|
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
|
-
- HY-112005GL
-
Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
|
Biochemical Assay Reagents
|
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-160275
-
|
Drug Delivery
|
DOPE-PEG-Fluor 555,MW 2000 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-145797
-
|
Drug Delivery
|
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
|
-
- HY-144023
-
|
Drug Delivery
|
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
|
-
- HY-112763
-
|
Drug Delivery
|
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
|
-
- HY-139200
-
DOTMA
1 Publications Verification
|
Drug Delivery
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
- HY-142997
-
|
Drug Delivery
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
- HY-131119
-
Dioctadecyldimethylammonium bromide; DODAB
|
Drug Delivery
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10968
-
|
Bacterial
Antibiotic
|
Infection
|
KT2 is a cationic amphipathic antibacterial peptide. KT2 can completely kill cells of E. coli O157:H7. KT2 has potent anti-biofilm activity and prevents biofilm formation of E. coli O157:H7. KT2 significantly binds to bacterial surface LPS and interacts with the lipids of liposomes with great penetration capability into bacterial cells, followed by bond to DNA and other cytoplasmic membrane .
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-112005
-
DOPE
5 Publications Verification
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
|
Phospholipids
|
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-144018
-
|
|
Phospholipids
|
18:1 EPC chloride is a cationic alkylated phospholipid and also an egg yolk phosphatidylcholine. 18:1 EPC chloride can be used in research on liposomes and drug delivery .
|
-
- HY-130751
-
DODAP
1 Publications Verification
|
|
Cationic Lipids
|
DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
|
-
- HY-144021
-
|
|
Cationic Lipids
|
14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
|
-
- HY-144025
-
|
|
Cationic Lipids
|
DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
|
-
- HY-139298
-
L319
1 Publications Verification
Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
|
|
Cationic Lipids
|
L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
|
-
- HY-160275
-
|
|
Pegylated Lipids
Fluorescent Lipids
|
DOPE-PEG-Fluor 555,MW 2000 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-145797
-
|
|
Cationic Lipids
|
L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
|
-
- HY-144023
-
|
|
Cationic Lipids
|
16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
|
-
- HY-W800782
-
|
|
Cationic Lipids
|
DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .
|
-
- HY-112763
-
|
|
Cationic Lipids
|
CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
|
-
- HY-139200
-
DOTMA
1 Publications Verification
|
|
Cationic Lipids
|
DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
|
-
- HY-W800783
-
CDESA
|
|
Cationic Lipids
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
-
- HY-W590549
-
DODAC
|
|
Cationic Lipids
|
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that can be used as transfection reagent .
|
-
- HY-W800776
-
1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide
|
|
Cationic Lipids
|
DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
|
-
- HY-112766
-
|
|
Phospholipids
|
DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
|
-
- HY-142997
-
|
|
Cationic Lipids
|
DOSPA is a cationicliposome. DOSPA can formulate with DNA to be a transfection system. DOSPA can be used for gene therapy research .
|
-
- HY-160581
-
|
|
Cationic Lipids
|
OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
|
-
- HY-131119
-
Dioctadecyldimethylammonium bromide; DODAB
|
|
Cationic Lipids
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
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