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Isoforms Recommended:	Caspase 6

Results for "

caspase-6

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Caspase (10) Apoptosis (1) Fluorescent Dye (2) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (3) Neurological Disease (3)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Antibodies

Oligonucleotides

Targets Recommended: Caspase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1007

Z-VEID-FMK Z-VE(OMe)ID(OMe)-FMK	Caspase Apoptosis	Cancer
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible *caspase-6* peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis .

HY-108312A

Ac-VEID-CHO TFA	Caspase	Neurological Disease
Ac-VEID-CHO (TFA) is a peptide-derived *caspase* inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-P5983

Ac-VEID-AFC 1 Publications Verification	Caspase	Cancer
Ac-VEID-AFC is a *caspase-6* fluorogenic substrate, and can be used in the caspase 6 activity assay .

HY-P10822

ED11	Caspase	Neurological Disease
ED11 is a potent and selective *caspase-6* inhibitor with an IC₅₀ of 12.12 nM. ED11 competes with Htt for the caspase-6 active site, and thus reduce Htt cleavage. ED11 can cross the blood-brain barrier (BBB). ED11 has the potential for the study of Huntington's disease (HD) .

HY-P2065

Ac-VEID-AMC	Fluorescent Dye	Others
Ac-VEID-AMC is a fluorescent substrate for the determination of *caspase-6* and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .

HY-P4401A

Z-VEID-AFC TFA	Fluorescent Dye Caspase	Others
Z-VEID-AFC TFA is the trifluoroacetate salt of Z-VEID-AFC (HY-P4401). Z-VEID-AFC TFA is a fluorescent substrate for caspase-6. When Z-VEID-AFC TFA is cleaved by caspase-6, 7-amino-4-trifluoromethylcoumarin (AFC) is released, and its fluorescence can be used to quantify caspase-6 activity (Ex/Em: 400/505 nm) .

HY-P4401

Z-VEID-AFC	Caspase	Others
Z-VEID-AFC is a fluorescent substrate for caspase-6 .

HY-108312

Ac-VEID-CHO	Caspase	Neurological Disease
Ac-VEID-CHO is a peptide-derived *caspase* inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO also inhibits VEIDase activity an IC₅₀ value of 0.49 µM. Ac-VEID-CHO can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-137038

N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride TLCK hydrochloride	Caspase Ser/Thr Protease	Cancer
N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride inhibits caspase-3, caspase-6 and caspase-7, with IC₅₀s of 12.0, 54.5 and 19.3 μM, respectively. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride induces apoptosis in cell HL-60, and inhibits the decrease in mitochondrial transmembrane potential during apoptosis .

HY-RS01959

CASP6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) Caspase	Others
CASP6 Human Pre-designed siRNA Set A contains three designed siRNAs for CASP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CASP6 Human Pre-designed siRNA Set A CASP6 Human Pre-designed siRNA Set A

HY-P2610

Ac-VEID-pNA	Caspase	Others
Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for *caspase 6*, that cleaves the lamin A at the cleavage site of VEID .

Cat. No.	Product Name	Type

HY-P2065

Ac-VEID-AMC	Fluorescent Dyes/Probes
Ac-VEID-AMC is a fluorescent substrate for the determination of *caspase-6* and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .

Cat. No.	Product Name	Target	Research Area

HY-P1007

Z-VEID-FMK Z-VE(OMe)ID(OMe)-FMK	Caspase Apoptosis	Cancer
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible *caspase-6* peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis .

HY-108312A

Ac-VEID-CHO TFA	Caspase	Neurological Disease
Ac-VEID-CHO (TFA) is a peptide-derived *caspase* inhibitor and has potency of inhibition for Caspase-6, Caspase-3 and Caspase-7 with IC₅₀ values of 16.2 nM, 13.6 nM and 162.1 nM, respectively. Ac-VEID-CHO (TFA) can be used for the research of neurodegenerative conditions including Alzheimer’s and Huntington’s disease .

HY-P5983

Ac-VEID-AFC 1 Publications Verification	Caspase	Cancer
Ac-VEID-AFC is a *caspase-6* fluorogenic substrate, and can be used in the caspase 6 activity assay .

HY-P10822

ED11	Caspase	Neurological Disease
ED11 is a potent and selective *caspase-6* inhibitor with an IC₅₀ of 12.12 nM. ED11 competes with Htt for the caspase-6 active site, and thus reduce Htt cleavage. ED11 can cross the blood-brain barrier (BBB). ED11 has the potential for the study of Huntington's disease (HD) .

HY-P2065

Ac-VEID-AMC	Fluorescent Dye	Others
Ac-VEID-AMC is a fluorescent substrate for the determination of *caspase-6* and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .

HY-P4401A

Z-VEID-AFC TFA	Fluorescent Dye Caspase	Others
Z-VEID-AFC TFA is the trifluoroacetate salt of Z-VEID-AFC (HY-P4401). Z-VEID-AFC TFA is a fluorescent substrate for caspase-6. When Z-VEID-AFC TFA is cleaved by caspase-6, 7-amino-4-trifluoromethylcoumarin (AFC) is released, and its fluorescence can be used to quantify caspase-6 activity (Ex/Em: 400/505 nm) .

HY-P4401

Z-VEID-AFC	Caspase	Others
Z-VEID-AFC is a fluorescent substrate for caspase-6 .

HY-P2610

Ac-VEID-pNA	Caspase	Others
Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for *caspase 6*, that cleaves the lamin A at the cleavage site of VEID .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80047

	Caspase-6 Antibody (YA556)	WB, ICC/IF, IHC-P, IP	Human, Mouse, Rat
	Caspase-6 Antibody (YA556) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-6.

HY-P80048

	Caspase-6 p18 Antibody (YA555)	WB	Human
	Caspase-6 p18 Antibody (YA555) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-6 p18.

HY-P81812

	Caspase-6 Antibody (YA1557) CASP6; MCH2; caspase-6; CASP-6; Apoptotic protease Mch-2	WB	Human, Rat
	Caspase-6 Antibody (YA1557) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-6.

HY-P86135

	Caspase-6 Antibody (YA5827) CASP6; MCH2; caspase-6; CASP-6; Apoptotic protease Mch-2	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Caspase-6 Antibody (YA5827) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-6.

HY-P84403

	Caspase-6 Antibody (YA4100) MCH2	ICC/IF, FC, ELISA	Human
	Caspase-6 Antibody (YA4100) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Caspase-6.

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Cat. No.	Product Name		Classification

HY-RS01959

CASP6 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CASP6 Human Pre-designed siRNA Set A contains three designed siRNAs for CASP6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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