caspase-12

Isoforms Recommended:	Caspase 12

By Targets:	Caspase (10) Apoptosis (15) Endogenous Metabolite (10) ERK (9) Isotope-Labeled Compounds (5) Reactive Oxygen Species (ROS) (2) Reference Standards (1)
By Research Areas:	Cancer (14)

Targets Recommended: Caspase URAT1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19696A

Tauroursodeoxycholate sodium Maximum Cited Publications 84 Publications Verification Tauroursodeoxycholic acid sodium; TUDCA sodium; UR 906 sodium	ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as *caspase-3* and *caspase-12. Tauroursodeoxycholate also inhibits ERK*.

HY-19696

Tauroursodeoxycholate Maximum Cited Publications 84 Publications Verification Tauroursodeoxycholic acid; TUDCA; UR 906	ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an orally active endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as *caspase-3* and *caspase-12. Tauroursodeoxycholate also inhibits ERK* .

HY-19696S

Tauroursodeoxycholate-d5	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₅ is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696AS

Tauroursodeoxycholate-d4 sodium Tauroursodeoxycholic acid-d₄ sodium; TUDCA-d₄ sodium; UR 906-d₄ sodium	Isotope-Labeled Compounds ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-123554

Flavagline FL3	Apoptosis	Cancer
Flavagline FL3 is a flavagline with potent and selective cytotoxicity in cancer cells.Flavagline FL3 induces apoptosis of HL60 and Hela cells by triggering the translocation of Apoptosis Inducing Factor (AIF) and caspase-12 to the nucleus .

HY-19696R

Tauroursodeoxycholate (Standard) Tauroursodeoxycholic acid (Standard); TUDCA (Standard); UR 906 (Standard)	Reference Standards ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate (Standard) is the analytical standard of Tauroursodeoxycholate. This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696AR

Tauroursodeoxycholate sodium (Standard) Tauroursodeoxycholic acid sodium (Standard); TUDCA sodium (Standard); UR 906 sodium (Standard)	ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate (sodium) (Standard) is the analytical standard of Tauroursodeoxycholate (sodium). This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-P10326

Z-ATAD-FMK	Caspase Apoptosis	Cancer
Z-ATAD-FMK is an inhibitor of *caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis* by inhibiting the activity of caspase-12 and reducing the activity of caspase-9 .

HY-19696BR

Tauroursodeoxycholate dihydrate (Standard)	ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate (dihydrate) (Standard) is the analytical standard of Tauroursodeoxycholate (dihydrate). This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK .

HY-19696S1

Tauroursodeoxycholate-d4 Tauroursodeoxycholic acid-d₄; TUDCA-d₄; UR 906-d₄	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S2

Tauroursodeoxycholate-d4-1 Tauroursodeoxycholic acid-d₄-1; TUDCA-d₄-1; UR 906-d₄-1	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B1899S

Taurodeoxycholic acid-d5	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis	Others
Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

HY-N0878

Bufotalin 4 Publications Verification	Apoptosis Reactive Oxygen Species (ROS)	Cancer
Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation .

HY-N0878R

Bufotalin (Standard)	Apoptosis Reactive Oxygen Species (ROS)	Cancer
Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation .

HY-167707

Q-VD(OMe)-OPh	Apoptosis	Cancer
Q-VD(OMe)-OPh is a broad-spectrum caspase inhibitor with high activity in inhibiting apoptosis. Q-VD(OMe)-OPh is not toxic to cells at high concentrations, demonstrating its safety. Q-VD(OMe)-OPh exhibits comparable effectiveness to other widely used inhibitors in preventing apoptosis mediated by caspase 9/3, caspase 8/10, and caspase 12 .

Cat. No.	Product Name	Target	Research Area

HY-P10326

Z-ATAD-FMK	Caspase Apoptosis	Cancer
Z-ATAD-FMK is an inhibitor of *caspase-12. Z-ATAD-FMK is an inhibitor of caspase-12. Z-ATAD-FMK prevents endoplasmic reticulum stress-mediated apoptosis* by inhibiting the activity of caspase-12 and reducing the activity of caspase-9 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-19696A

Tauroursodeoxycholate sodium Maximum Cited Publications 84 Publications Verification Tauroursodeoxycholic acid sodium; TUDCA sodium; UR 906 sodium	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	ERK Caspase Apoptosis Endogenous Metabolite
Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as *caspase-3* and *caspase-12. Tauroursodeoxycholate also inhibits ERK*.

HY-19696

Tauroursodeoxycholate Maximum Cited Publications 84 Publications Verification Tauroursodeoxycholic acid; TUDCA; UR 906	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	ERK Caspase Endogenous Metabolite Apoptosis
Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an orally active endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as *caspase-3* and *caspase-12. Tauroursodeoxycholate also inhibits ERK* .

HY-N0878

Bufotalin 4 Publications Verification	Structural Classification Animals Classification of Application Fields Source classification Disease Research Fields Steroids Cancer	Apoptosis Reactive Oxygen Species (ROS)
Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation .

HY-19696R

Tauroursodeoxycholate (Standard) Tauroursodeoxycholic acid (Standard); TUDCA (Standard); UR 906 (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Reference Standards ERK Caspase Endogenous Metabolite Apoptosis
Tauroursodeoxycholate (Standard) is the analytical standard of Tauroursodeoxycholate. This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696AR

Tauroursodeoxycholate sodium (Standard) Tauroursodeoxycholic acid sodium (Standard); TUDCA sodium (Standard); UR 906 sodium (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	ERK Caspase Apoptosis Endogenous Metabolite
Tauroursodeoxycholate (sodium) (Standard) is the analytical standard of Tauroursodeoxycholate (sodium). This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696BR

Tauroursodeoxycholate dihydrate (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	ERK Caspase Apoptosis Endogenous Metabolite
Tauroursodeoxycholate (dihydrate) (Standard) is the analytical standard of Tauroursodeoxycholate (dihydrate). This product is intended for research and analytical applications. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK .

HY-N0878R

Bufotalin (Standard)	Structural Classification Animals Source classification Steroids	Apoptosis Reactive Oxygen Species (ROS)
Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation .

Cat. No.	Product Name	Chemical Structure

HY-19696S

Tauroursodeoxycholate-d5
Tauroursodeoxycholate-d₅ is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B1899S

Taurodeoxycholic acid-d5
Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

Taurodeoxycholic acid-d5

Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S2

Tauroursodeoxycholate-d4-1
Tauroursodeoxycholate-d₄-1 is the deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81095

	Caspase-12 Antibody (YA3489) CASP 12 antibody; CASP-12 antibody; Casp12 antibody; CASP12P1 antibody; caspase 12 (gene/pseudogene) antibody; caspase 12 pseudogene 1 antibody; CASPC_HUMAN antibody; Inactive caspase-12 antibody; OTTHUMP00000207032 antibody;	WB, IHC-P	Human, Mouse, Rat
	Caspase-12 Antibody (YA3489) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspase-12.

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