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Results for "

cardiac defect

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W099479
    Insect repellent M 3535

    Ethyl butylacetylaminopropionate; IR-3535

    		 Reactive Oxygen Species (ROS) Apoptosis Cardiovascular Disease Inflammation/Immunology
    Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf). Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway .
    Insect repellent M 3535
  • HY-19987
    BML-284
    Maximum Cited Publications
    28 Publications Verification

    		 Wnt Cancer
    BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM .
    BML-284
  • HY-N1487
    Oleanonic acid
    1 Publications Verification

    3-Oxooleanolic acid

    		 HIV Autophagy Ferroptosis Amyloid-β Infection Neurological Disease Inflammation/Immunology Cancer
    Oleanonic acid (3-Oxooleanolic acid) is an orally available triterpene that has anti-inflammatory and insecticidal properties. In vitro, oleanonic acid can improve oxidative stress, autophagy defects, ferroptosis, mitochondrial damage, and endoplasmic reticulum stress induced by Amyloid-β, and in vivo, it can alleviate myocardial hypertrophy in rats .
    Oleanonic acid
  • HY-19987R
    BML-284 (Standard)

    		Wnt Cancer
    BML-284 (Standard) is the analytical standard of BML-284. This product is intended for research and analytical applications. BML-284 is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM .
    BML-284 (Standard)
  • HY-19987A
    BML-284 hydrochloride

    		Wnt Cancer
    BML-284 hydrochloride is a potent and cell-permeable Wnt signaling activator. BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM .
    BML-284 hydrochloride
  • HY-W099479R
    Insect repellent M 3535 (Standard)

    Ethyl butylacetylaminopropionate (Standard); IR-3535 (Standard)

    		 Reference Standards Reactive Oxygen Species (ROS) Apoptosis Cardiovascular Disease Inflammation/Immunology
    Insect repellent M 3535 (Standard) is the analytical standard of Insect repellent M 3535. This product is intended for research and analytical applications. Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a novel potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf). Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway .
    Insect repellent M 3535 (Standard)
  • HY-N8321R
    5-O-Caffeoylshikimic acid (Standard)

    		Reference Standards Others Cancer
    Insect repellent M 3535 (Standard) is the analytical standard of Insect repellent M 3535. This product is intended for research and analytical applications. Insect repellent M 3535 (Ethyl butylacetylaminopropionate; IR-3535) is a novel potent anthelmintic that is toxic to zebrafish with a lethal concentration 50 (LC50) of 140 mg/L at 72 hours post fertilization (hpf). Insect repellent M 3535 causes morphological abnormalities and cardiac defects in early embryonic development of zebrafish by potentially inducing the production and accumulation of reactive oxygen species (Reactive Oxygen Species) and activating oxidative stress responses, thereby activating the endogenous apoptosis pathway .
    5-O-Caffeoylshikimic acid (Standard)

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