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Results for "

antibiotic-resistant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (6) 5-HT Receptor (2) Bacterial (21) Dopamine Receptor (2) Reference Standards (1) Reverse Transcriptase (1)
By Research Areas:	Infection (24) Neurological Disease (2)

Inhibitors & Agonists

Peptides

Natural
Products

Targets Recommended: Antibiotic

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P10233A

SAAP 148 TFA	Bacterial	Infection
SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM .

HY-128384

Benzyldodecyldimethylammonium chloride dihydrate	Bacterial	Infection
Benzyldodecyldimethylammonium chloride dihydrate is a quaternary ammonium compound (QAC) and can be used as a biocide to target antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant (MDR) P. aeruginosa et. al. Benzyldodecyldimethylammonium chloride dihydrate, an antimicrobial agent, bacteriostatic or bactericidal properties depending on the concentration.

HY-165272

Antibiotic SF-2132	Bacterial Antibiotic	Infection
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .

HY-126629

Antibacterial agent 12	Bacterial	Infection
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria .

HY-151567

Antibacterial agent 123	Bacterial	Infection
Antibacterial agent 123 (compound 111) is a potent membrane-disrupting agent to combat antibiotic-resistant Gram-positive bacteria .

HY-178347

Debio 1453	Bacterial	Infection
Debio 1453 is a bactericidal FabI inhibitor potent against N. gonorrhoeae (IC₅₀ = 0.6 nM), including drug-resistant strains. Debio 1453 demonstrates a low propensity for resistance selection and is effective in eradicating both planktonic and intracellular bacteria through a mechanism of concurrently inhibiting FabI and engaging the non-mutable NADH cofactor. Debio 1453 clears antibiotic-resistant N. gonorrhoeae infection in a murine vaginal model. Debio 1453 can be used for gonorrhoea research .

HY-106590

Saccharocin antibiotic KA 5685	Bacterial	Infection
Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .

HY-129166

UCM53	Bacterial	Infection
UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis

HY-P10233

SAAP 148	Bacterial	Infection
SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM .

HY-P1872

OV-1, sheep	Bacterial	Infection
OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep), which inhibits several antibiotic-resistant bacterial strains including mucoid and nonmucoid Pseudomonas aeruginosa .

HY-N0315

Allicin Maximum Cited Publications 14 Publications Verification Diallyl thiosulfinate	Bacterial Antibiotic	Infection
Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains .

HY-149333

BO-1	Bacterial	Infection
BO-1 is a benzoate ester with antibacterial activity. BO-1 inhibits multidrug-resistant Staphylococcus aureus, and acts function synergistically with antibiotic, such as Ciprofloxacin (HY-B0356). BO-1 can reverse the resistance of antibiotic-resistant S. aureus strains, and decreases the level of inflammatory factors IL-6 and C-reactive protein in vivo in mice .

HY-A0279

Pristinamycin Pristinamycine	Bacterial Antibiotic	Infection
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-W773487

FtsZ-IN-10	Bacterial	Infection
FtsZ-IN-10 is a bacterial division inhibitor that interferes with the normal assembly of FtsZ. FtsZ-IN-10 specifically binds to Bacillus subtilis FtsZ monomers, thereby affecting their polymerization behavior. FtsZ-IN-10 may also activate nucleotide-free archaeal FtsZ to form ordered polymers. FtsZ-IN-10 can hinder the localization of FtsZ in the Z ring and inhibit bacterial cell division. Chlorinated analogs of FtsZ-IN-10 show the ability to inhibit the growth of antibiotic-resistant clinical isolates such as Staphylococcus aureus and Enterococci .

HY-N7545

Protorubradirin	Antibiotic Reverse Transcriptase	Infection
Protorubradirin is an antibiotic that can be isolated from Streptomyces achromogenes var. rubradirin together with Rubradirin. Protorubradirin has inhibitory activity against HIV reverse transcriptase. In vitro studies have shown that Protorubradirin also inhibits Staphylococcus aureus strains and Streptococci. In infected mice, subcutaneous injection of Protorubradirin showed in vivo inhibitory efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may result in a significant reduction in the activity of Protorubradirin, possibly due to faster cleavage of its C-nitroso sugar in the acidic gastric environment compared to Rubradirin .

HY-N14653

Glysperin A	Bacterial	Infection
Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-N15526

Austroside A	Bacterial	Infection
Austroside A is found in Evodia austrosinensis. Austroside A shows antibacterial activity against the Staphylococcus aureus antibiotic resistant strain .

HY-N14680

Glysperin C	Bacterial	Infection
Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-N14654

Glysperin B	Bacterial	Infection
Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

HY-125745

Loloatin B 10	Antibiotic Bacterial	Infection
Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens .

HY-17390A

Loxapine succinate 1 Publications Verification	5-HT Receptor Dopamine Receptor	Infection Neurological Disease
Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .

HY-16485

Telavancin hydrochloride 1 Publications Verification TD-6424 hydrochloride	Antibiotic Bacterial	Infection
Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) .

HY-17390AR

Loxapine succinate (Standard)	Reference Standards 5-HT Receptor Dopamine Receptor	Infection Neurological Disease
Loxapine (succinate) (Standard) is the analytical standard of Loxapine (succinate). This product is intended for research and analytical applications. Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages .

HY-139798

Iboxamycin	Bacterial	Infection
Iboxamycin is a potent *antibiotic* candidate bearing a fused bicyclic amino acid residue. Iboxamycin is orally bioavailable, safe and effective in researching both Gram-positive and Gram-negative bacterial infections in mice .

Cat. No.	Product Name	Target	Research Area

HY-P10233A

SAAP 148 TFA	Bacterial	Infection
SAAP 148 TFA is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM .

HY-P10233

SAAP 148	Bacterial	Infection
SAAP 148 is an antimicrobial and antibiofilm agent, and exhibits inhibitory efficacy against antibiotic-resistant pathogens, with LC₅₀ of 0.8-12.8 μM .

HY-P1872

OV-1, sheep	Bacterial	Infection
OV-1, sheep is an alpha-helical antimicrobial ovispirin peptide derived from SMAP29 peptide (sheep), which inhibits several antibiotic-resistant bacterial strains including mucoid and nonmucoid Pseudomonas aeruginosa .

HY-125745

Loloatin B 10	Antibiotic Bacterial	Infection
Loloatin B 10 is an antibiotic, which exhibits antibacterial efficacy against gram positive antibiotic resistant human pathogens .

Allicin 10+ Cited Publications Diallyl thiosulfinate	Infection Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Bacterial Antibiotic
Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains .

Pristinamycin Pristinamycine	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

Antibiotic SF-2132	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Antibiotic
Antibiotic SF-2132 is a peptide antibiotic identified in Nocardiopsis sp., which exhibits inhibitory activity against β-lactam antibiotic-resistant strains, such as Pseudomonas and Escherichia .

Saccharocin antibiotic KA 5685	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Saccharocin (Antibiotic KA 5685) is effective against Gram-positive and negative bacteria, and also against aminoglycoside antibiotic-resistant bacteria .

Protorubradirin	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Reverse Transcriptase
Protorubradirin is an antibiotic that can be isolated from Streptomyces achromogenes var. rubradirin together with Rubradirin. Protorubradirin has inhibitory activity against HIV reverse transcriptase. In vitro studies have shown that Protorubradirin also inhibits Staphylococcus aureus strains and Streptococci. In infected mice, subcutaneous injection of Protorubradirin showed in vivo inhibitory efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may result in a significant reduction in the activity of Protorubradirin, possibly due to faster cleavage of its C-nitroso sugar in the acidic gastric environment compared to Rubradirin .

Glysperin A	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin A has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

Austroside A	Annona squamosa L. Source classification Plants Annonaceae Saccharides Monosaccharides	Bacterial
Austroside A is found in Evodia austrosinensis. Austroside A shows antibacterial activity against the Staphylococcus aureus antibiotic resistant strain .

Glysperin C	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin C has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

Glysperin B	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Glysperin B has anti-Gram positive bacteria and negative bacteria (including aminoglycoside antibiotic resistant bacteria) activity .

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antibiotic-resistant

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