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anthracis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (10) Bacterial (15) Endogenous Metabolite (1) Parasite (1)
By Research Areas:	Cancer (3) Infection (15) Inflammation/Immunology (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-76260

Faropenem sodium 1 Publications Verification	Bacterial Antibiotic	Infection
Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis .

HY-17586

Dalbavancin hydrochloride Maximum Cited Publications 6 Publications Verification MDL-63397 hydrochloride; BI-397 hydrochloride	Bacterial Antibiotic	Infection
Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits *Staphylococcus aureus* and Bacillus anthracis with MIC₉₀s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-P9957

Raxibacumab ABthrax	Bacterial	Infection
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research .

HY-N2567

(±)-Decursinol	Bacterial	Infection Cancer
(±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC₅₀ of 102 μM .

HY-164123

Antibiofilm agent-9	Bacterial	Infection
Antibiofilm agent-9 (Compound 4) is a pyrrolomycin derivative with antibacterial activity. Antibiofilm agent-9 inhibits Bacillus anthracis with MIC of 0.031 μg/mL. Antibiofilm agent-9 exhibits antibiofilm activity with 84% biofilm inhibition (24 h, 8.0 μg/mL). Antibiofilm agent-9 exhibits a good pharmacokinetic characters in mouse model .

HY-17586A

Dalbavancin MDL-63397; BI-397	Bacterial Antibiotic	Infection
Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits *Staphylococcus aureus* and Bacillus anthracis with MIC₉₀s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-P5548

CaLL	Bacterial	Infection Cancer
CaLL is an antimicrobial peptide. CaLL has antibacterial activity against B. anthracis, B. anthracis* (vegetative), and B. cepacia* (MIC: 7.8, 31.3, 31.3 μg/mL) .

HY-P5691

P1	Bacterial	Infection Cancer
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .

HY-17586AS

Dalbavancin-d6 MDL-63397-d₆; BI-397-d₆	Bacterial Antibiotic	Infection
Dalbavancin-d₆ is the deuterium labeled Dalbavancin . Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .

HY-117831

NSC-79887	Bacterial Antibiotic Endogenous Metabolite	Infection
NSC-79887 is a nucleoside hydrolase (NH) inhibitor with activity against Bacillus anthracis. NSC-79887 is considered a good candidate inhibitor of nucleoside hydrolases for biological testing and further development. The pharmacokinetic (ADMET) prediction of NSC-79887 showed that all physicochemical parameters were within the acceptable range for human use .

HY-A0035

Faropenem	Antibiotic Bacterial	Infection
Faropenem is a potent and orally active beta-lactam antibiotic. Faropenem demonstrates broad-spectrum in vitro antimicrobial activity against many gram-positive and -negative aerobes and anaerobes. Faropenem is resistant to hydrolysis by nearly all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Faropenem is developed as an oral proagent, faropenem medoxomil, for the research of respiratory tract infections .

HY-B1831

Oritavancin LY 333328; Orbactiv	Antibiotic Bacterial	Infection Inflammation/Immunology
Oritavancin (LY 333328), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

HY-B1831A

Oritavancin diphosphate 1 Publications Verification LY333328 diphosphate	Bacterial Antibiotic	Infection Inflammation/Immunology
Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

HY-136943

K-41	Antibiotic Parasite Bacterial	Infection
K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity .

HY-B1831AR

Oritavancin (diphosphate) (Standard)	Bacterial Antibiotic	Infection Inflammation/Immunology
Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity .

Cat. No.	Product Name	Target	Research Area

HY-P5548

CaLL	Bacterial	Infection Cancer
CaLL is an antimicrobial peptide. CaLL has antibacterial activity against B. anthracis, B. anthracis* (vegetative), and B. cepacia* (MIC: 7.8, 31.3, 31.3 μg/mL) .

HY-P5691

P1	Bacterial	Infection Cancer
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .

Cat. No.	Product Name	Target	Research Area

HY-P9957

Raxibacumab ABthrax	Bacterial	Infection
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2567

(±)-Decursinol	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
(±)-Decursinol is a potent FtsZ inhibitor. (±)-Decursinol inhibits B. anthracis FtsZ polymerization with an IC₅₀ of 102 μM .

HY-136943

K-41	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Antibiotic Parasite Bacterial
K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity .

Cat. No.	Compare	Product Name	Species	Source

HY-P72177

	*TMK Protein, Bacillus anthracis* (His)** tmk; BAMEG_0039Thymidylate kinase; EC 2.7.4.9; dTMP kinase	Others	E. coli
	TMK proteins play a central role by catalyzing the phosphorylation of deoxythymidine monophosphate (dTMP), a key step in the synthesis of deoxythymidine triphosphate (dTTP). This process converts dTMP into deoxythymidine diphosphate (dTDP), an important intermediate in dTTP biosynthesis. TMK Protein, Bacillus anthracis (His) is the recombinant TMK protein, expressed by E. coli , with N-6*His labeled tag.

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HY-17586AS

Dalbavancin-d6
Dalbavancin-d₆ is the deuterium labeled Dalbavancin . Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .

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anthracis

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Natural
Products