Search Result
Results for "
alkynyl group
" in MedChemExpress (MCE) Product Catalog:
17
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-115495
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Biochemical Assay Reagents
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Others
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6-Alkynyl fucose is a tool in the study of protein O-fucosylation . 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140335
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PROTAC Linkers
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Cancer
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Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W040304
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Alk-C16
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PROTAC Linkers
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Cancer
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Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl Palmitic Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2911
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Biochemical Assay Reagents
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Metabolic Disease
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Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
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- HY-116879
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(2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE
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Biochemical Assay Reagents
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Cancer
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4-Oxo-2-Nonenal Alkyne ((2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE) is a functionalized lipid electrophile that conjugated to the exosomes via the reaction of amino and aldehyde groups. 4-Oxo-2-Nonenal Alkyne can be used in tumor exosomes determination .
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- HY-140875
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Drug Intermediate
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Others
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Propargyl-PEG3-triethoxysilane contains a triethoxysilane moiety and an alkynyl group. Propargyl-PEG3-triethoxysilane can be used for material surface modification, biological molecule labeling, immobilization, and so on.
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- HY-W1049091D
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 40000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091B
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 10000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860B
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Biochemical Assay Reagents
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Others
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4-Arm PEG-alkyne (MW 10000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1048860D
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Biochemical Assay Reagents
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Others
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4-Arm PEG-alkyne (MW 40000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1049091A
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 5000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049105
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 2000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860A
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Biochemical Assay Reagents
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Others
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4-Arm PEG-alkyne (MW 5000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1049091
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 1000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091C
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 20000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091E
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Biochemical Assay Reagents
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Others
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mPEG-Alkyne (MW 3400) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860C
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Biochemical Assay Reagents
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Others
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4-Arm PEG-alkyne (MW 20000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-174969
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Biochemical Assay Reagents
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Others
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Alkyne-PEG-Silane (MW 1000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 1000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 1000) to modify surfaces such as glass and silicon .
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- HY-174969C
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Biochemical Assay Reagents
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Others
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Alkyne-PEG-Silane (MW 5000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 5000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 5000) to modify surfaces such as glass and silicon .
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- HY-174969A
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Biochemical Assay Reagents
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Others
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Alkyne-PEG-Silane (MW 2000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 2000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 2000) to modify surfaces such as glass and silicon .
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- HY-174969B
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Biochemical Assay Reagents
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Others
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Alkyne-PEG-Silane (MW 3400) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 3400) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 3400) to modify surfaces such as glass and silicon .
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- HY-170528
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PROTAC Linkers
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Others
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DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
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- HY-174946A
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DPPE-PEG5-N3
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Biochemical Assay Reagents
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Others
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DPPE-PEG5-azide (DPPE-PEG5-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG5-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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- HY-174946
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DPPE-PEG1-N3
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Biochemical Assay Reagents
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Others
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DPPE-PEG1-azide (DPPE-PEG1-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG1-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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- HY-D2161A
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Fluorescent Dye
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Others
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AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne) .
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- HY-W457950
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E3 Ligase Ligand-Linker Conjugates
Autophagy
Apoptosis
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Cancer
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Thalidomide-5-propargyl is a propargyl-modified Thalidomide (HY-14658), that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-5-propargyl use alkynyl group at the end to be directly used in the synthesis of triazoles in the synthesis of PROTAC molecules, and is a key intermediate in the synthesis of PROTAC molecules based on CRBN design .
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- HY-D2161
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Fluorescent Dye
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Others
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AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-173578
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Biochemical Assay Reagents
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Others
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N-(2-Poc-ethyl)betulin amide is a triterpenoid with antiviral and antitumor activities. N-(2-Poc-ethyl)betulin amide contains a Poc (prop-2-yn-1-yloxycarbonyl) alkynyl protecting group, which allows for bioorthogonal reactions (such as click chemistry) and is used for targeted delivery and fluorescent labeling .
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- HY-D2112
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Fluorescent Dye
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Others
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TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2111
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Fluorescent Dye
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Others
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TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-157515
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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Cat. No. |
Product Name |
Type |
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- HY-D2161A
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Fluorescent Dyes/Probes
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AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne) .
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- HY-D2911
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Fluorescent Dyes/Probes
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Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
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- HY-D2161
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Fluorescent Dyes/Probes
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AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-D2112
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Fluorescent Dyes/Probes
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TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2111
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Fluorescent Dyes/Probes
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TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No. |
Product Name |
Type |
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- HY-W1049091D
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Drug Delivery
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mPEG-Alkyne (MW 40000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091B
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Drug Delivery
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mPEG-Alkyne (MW 10000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860B
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Drug Delivery
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4-Arm PEG-alkyne (MW 10000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1048860D
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Drug Delivery
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4-Arm PEG-alkyne (MW 40000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1049091A
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Drug Delivery
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mPEG-Alkyne (MW 5000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049105
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Drug Delivery
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mPEG-Alkyne (MW 2000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860A
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Drug Delivery
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4-Arm PEG-alkyne (MW 5000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-W1049091
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Drug Delivery
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mPEG-Alkyne (MW 1000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091C
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Drug Delivery
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mPEG-Alkyne (MW 20000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091E
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Drug Delivery
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mPEG-Alkyne (MW 3400) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1048860C
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Drug Delivery
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4-Arm PEG-alkyne (MW 20000) is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
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- HY-174969
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Drug Delivery
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Alkyne-PEG-Silane (MW 1000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 1000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 1000) to modify surfaces such as glass and silicon .
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- HY-174969C
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Drug Delivery
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Alkyne-PEG-Silane (MW 5000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 5000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 5000) to modify surfaces such as glass and silicon .
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- HY-174969A
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Drug Delivery
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Alkyne-PEG-Silane (MW 2000) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 2000) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 2000) to modify surfaces such as glass and silicon .
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- HY-174969B
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Drug Delivery
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Alkyne-PEG-Silane (MW 3400) is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG-Silane (MW 3400) is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG-Silane (MW 3400) to modify surfaces such as glass and silicon .
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- HY-174946A
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DPPE-PEG5-N3
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Drug Delivery
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DPPE-PEG5-azide (DPPE-PEG5-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG5-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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- HY-174946
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DPPE-PEG1-N3
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Drug Delivery
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DPPE-PEG1-azide (DPPE-PEG1-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG1-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Cat. No. |
Product Name |
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Classification |
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- HY-115495
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Alkynes
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6-Alkynyl fucose is a tool in the study of protein O-fucosylation . 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140335
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PROTAC Synthesis
Alkynes
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Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W040304
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Alk-C16
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Alkynes
PROTAC Synthesis
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Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl Palmitic Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W1049091D
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Alkynes
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mPEG-Alkyne (MW 40000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091B
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Alkynes
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mPEG-Alkyne (MW 10000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091A
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Alkynes
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mPEG-Alkyne (MW 5000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049105
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Alkynes
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mPEG-Alkyne (MW 2000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091
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Alkynes
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mPEG-Alkyne (MW 1000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091C
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Alkynes
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mPEG-Alkyne (MW 20000) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-W1049091E
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Alkynes
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mPEG-Alkyne (MW 3400) is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
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- HY-170528
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DBCO
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DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
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- HY-D2161
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Azide
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AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-D2112
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Labeling and Fluorescence Imaging
Azide
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TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-D2111
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Labeling and Fluorescence Imaging
Azide
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TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-157515
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Azide
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Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
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