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Results for "

acyl-CoA synthetase inhibitor

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-117651
    2-Fluoropalmitic acid

    		Acyltransferase Cancer
    2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines .
    2-Fluoropalmitic acid
  • HY-W015444
    2-Hydroxyoctanoic acid

    		Endogenous Metabolite Metabolic Disease
    2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM .
    2-Hydroxyoctanoic acid
  • HY-141699
    FATP1-IN-1
    1 Publications Verification

    		 FATP Metabolic Disease
    FATP1-IN-1 (compound 5k) is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively .
    FATP1-IN-1
  • HY-N6707
    Triacsin C
    5 Publications Verification

    WS 1228A; FR 900190

    		 Parasite Infection Cardiovascular Disease
    Triacsin C (WS 1228A), is an orally active and intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, which can be isolated from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity . Triacsin C exhibits highly inhibitory effect against rotavirus replication .
    Triacsin C
  • HY-148104
    ACSS2-IN-2
    1 Publications Verification

    		 Acetyl-CoA synthetase Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer .
    ACSS2-IN-2
  • HY-W015444R
    2-Hydroxyoctanoic acid (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    2-Hydroxyoctanoic acid (Standard) is the analytical standard of 2-Hydroxyoctanoic acid. This product is intended for research and analytical applications. 2-Hydroxyoctanoic acid is a medium chain acyl-CoA synthetase inhibitor with a Ki of 500 μM[1].
    2-Hydroxyoctanoic acid (Standard)
  • HY-173432
    LIBX-A401

    		Small Interfering RNA (siRNA) Others
    LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) (IC50 = 0.38 μM). LIBX-A401 has selectivity for ACSL4 over ACSL3 (IC50 over 50 μM) and PPARγ (IC50 over 10 μM) .
    LIBX-A401
  • HY-175328
    LIBX-A403

    		Ferroptosis Neurological Disease Cancer
    LIBX-A403 (Compound 21) is a highly selective acyl-CoA synthetase long-chain family member 4 (ACSL4) inhibitor (IC50=0.049 μM). LIBX-A403 blocks ACSL4-mediated ferroptosis-promoting phospholipid remodeling. LIBX-A403 is promising for research of cancers (e.g., triple-negative breast cancer) and neurodegenerative diseases (e.g., Parkinson’s disease) .
    LIBX-A403
  • HY-117651R
    2-Fluoropalmitic acid (Standard)

    		Reference Standards Acyltransferase Cancer
    Quinine (sulfate hydrate) (Standard) is the analytical standard of Quinine (sulfate hydrate). This product is intended for research and analytical applications. Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC50 of 169 μM .
    2-Fluoropalmitic acid (Standard)

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