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Zeleciment basivarsen

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-177452
    Zeleciment basivarsen

    DYNE-101

    		 Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor Others
    Zeleciment basivarsen (DYNE-101) is an antibody-oligonucleotide conjugate (AOC) that consists of a TfR1-binding Fab Zeleciment (HY-P990780) conjugated to an antisense oligonucleotide Basivarsen (HY-177453). This conjugate designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).
    Zeleciment basivarsen
  • HY-177454
    Basivarsen linker

    		ADC Linker Others
    Basivarsen linker is a linker used in HY-177452 Zeleciment basivarsen for coupling a TfR1-binding Fab (HY-P990780 Zeleciment) and an antisense oligonucleotide. Zeleciment basivarsen is an antibody-oligonucleotide conjugate (AOC) designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).
    Basivarsen linker

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