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VEGFR-2-IN-5

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18625A
    VEGFR-2-IN-5 hydrochloride

    		VEGFR Cancer
    VEGFR-2-IN-5 hydrochloride is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69 .
    VEGFR-2-IN-5 hydrochloride
  • HY-18625
    VEGFR-2-IN-5

    		VEGFR Cancer
    VEGFR-2-IN-5 is a VEGFR2 inhibitor extracted from patent WO2013055780A1, Page 69 .
    VEGFR-2-IN-5
  • HY-163710
    hCA/VEGFR-2-IN-5

    		VEGFR Carbonic Anhydrase Cancer
    hCA/VEGFR-2 IN-5 (compound 9) is an indolone-phenylsulfonamide and a potential dual inhibitor of cancer-related hCA IX/XII and VEGFR-2. The IC50 values of hCA/VEGFR-2-IN-5 for VEGFR-2, hCA IX and hCA XII are 0.38 μM, 40 and 3.2 nM, respectively. hCA/VEGFR-2-IN-5 has antitumor activity .
    hCA/VEGFR-2-IN-5
  • HY-172179
    EGFR/VEGFR2-IN-5

    		EGFR VEGFR Cancer
    EGFR/VEGFR2-IN-5 (Compound 14) is an orally active dual inhibitor of EGFR and VEGFR2 with an IC50 value of 1.15 µM for VEGFR2 and an IC50 value of 0.28 μM for EGFR T790M. EGFR/VEGFR2-IN-5 has significant anticancer activity .
    EGFR/VEGFR2-IN-5
  • HY-156638
    TIE-2/VEGFR-2 kinase-IN-5

    		Tie VEGFR Cardiovascular Disease
    TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. TIE-2/VEGFR-2 kinase-IN-5 also is a potent TIE-2 and VEGFR-2 tyrosine kinase inhibitor with pIC50 values of 7.78 nM and 8.11 nM, respectively. TIE-2/VEGFR-2 kinase-IN-5 can be used for the research of angiogenesis .
    TIE-2/VEGFR-2 kinase-IN-5

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