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VCP-Eribulin

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128870
    Mal-PEG2-VCP-Eribulin

    		Drug-Linker Conjugates for ADC Cancer
    Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin (HY-13442). Eribulin is a mechanistically unique microtubule inhibitor and Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Mal-PEG2-VCP-Eribulin is an Eribulin-based agent for antibody conjugates .
    Mal-PEG2-VCP-Eribulin
  • HY-128871
    VCP-Eribulin

    		Drug-Linker Conjugates for ADC Cancer
    VCP-Eribulin consists the ADCs linker (VCP) and Eribulin . Eribulin is a mechanistically unique microtubule inhibitor for cancer . VCP-Eribulin is an Eribulin-based agent for antibody conjugates .
    VCP-Eribulin
  • HY-177549
    Fmoc-PEG6-VCP-Eribulin

    		Drug Derivative ADC Payload Microtubule/Tubulin Apoptosis Cancer
    Fmoc-PEG6-VCP-Eribulin is the derivative of Eribulin (HY-13442). Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules .
    Fmoc-PEG6-VCP-Eribulin
  • HY-177414
    BB-1701

    		Antibody-Drug Conjugates (ADCs) EGFR Inflammation/Immunology Cancer
    BB-1701 is an anti-HER2 antibody-drug conjugate (ADC). BB-1701 is composed of a humanized anti-HER2 antibody (Trastuzumab) (HY-P9907), a linker (Mal-PEG2-VCP), a microtubule inhibitor (Eribulin) (HY-13442), and the drug-linker conjugate for ADC is Mal-PEG2-VCP-Eribulin (HY-128870). BB-1701 has a potent cytotoxicity and bystander effects on tumors with heterogeneous target expression. BB-1701 significantly induces immunogenic cell death and the activation of the immune .
    BB-1701

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