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Unpaired guanine residues

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175761
    Riboswit-modulator-1

    		Others Others
    Riboswit-modulator-1 (Compound A1), a covalent RNA ligand, is a Flavin mononucleotide (FMN) riboswitch modulator. Riboswit-modulator-1 modifies unpaired guanine residues (G11 and G62) proximal to the FMN-binding site through a proximity-driven mechanism, and interferes with its conformational transitions. Riboswit-modulator-1 acts as a negative antagonist by eliciting the opposite effect of the natural effector molecule .
    Riboswit-modulator-1

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