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Tanespimycin (Standard)

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10211R
    Tanespimycin (Standard)

    17-AAG (Standard); NSC 330507 (Standard); CP 127374 (Standard)

    		 Reference Standards HSP Autophagy Mitophagy Bacterial Apoptosis Antibiotic Infection Cancer
    Tanespimycin (Standard) is the analytical standard of Tanespimycin. This product is intended for research and analytical applications. Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression .
    Tanespimycin (Standard)

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