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Results for "

TPE

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Carboxylesterase (CES) (1) Caspase (1) Fluorescent Dye (3) Huntingtin (1) Parasite (1) Phosphatase (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (3) Infection (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D2639

TPE-PY	Fluorescent Dye	Metabolic Disease
TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .

HY-143218

TPE-MI 5+ Cited Publications Tetraphenylethene maleimide	Huntingtin Parasite	Infection Neurological Disease
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .

HY-149865

TPE-1p	Phosphatase Fluorescent Dye	Cancer
TPE-1p is a cascade-activated AIEgen-peptide probe. TPE-1p self-assembles in aqueous solution to exhibit bright fluorescence in response to alkaline phosphatase (ALP) and ChT-L. TPE-1p can be utilized to noninvasively assess the inhibition efficiency of a ChT-L inhibitor in cells .

HY-P6285

*Z-TPE-2DEVD*	Fluorescent Dye Caspase	Cancer
Z-TPE-2DEVD is a specific probe for caspase-3 .

HY-147915

Benz-AP	Carboxylesterase (CES) Reactive Oxygen Species (ROS)	Cancer
Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .

Cat. No.	Product Name	Type

HY-D2639

TPE-PY	Fluorescent Dyes/Probes
TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .

TPE-PY

Fluorescent Dyes/Probes

TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .

HY-143218

TPE-MI 5+ Cited Publications Tetraphenylethene maleimide	Fluorescent Dyes/Probes
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .

TPE-MI

5+ Cited Publications

Tetraphenylethene maleimide

Fluorescent Dyes/Probes

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .

*Z-TPE-2DEVD*	Fluorescent Dye Caspase	Cancer
Z-TPE-2DEVD is a specific probe for caspase-3 .

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