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Results for "

TMV Inhibitor

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163999
    TMV-IN-12

    		TMV Infection
    TMV-IN-12 (compound 4) is an inhibitor of tobacco mosaic virus (TMV) with antifungal properties. TMV-IN-12 effectively prevents TMV particle aggregation and self-assembly of TMV capsid protein (TMV-CP) (Kd=0.142 μM), preventing TMV from infecting tobacco plants .
    TMV-IN-12
  • HY-152259
    TMV-IN-4

    		TMV Infection
    TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco .
    TMV-IN-4
  • HY-161955
    TMV-IN-11

    		TMV Infection
    TMV-IN-11 (compound syn-3g) is a potent TMV inhibitor with high inactivation capacity (IC50: 120.7 μg/mL). TMV-IN-11 can effectively inhibit the expression of TMV .
    TMV-IN-11
  • HY-148569
    TMV-IN-3

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor .
    TMV-IN-3
  • HY-148568
    TMV-IN-2

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor .
    TMV-IN-2
  • HY-155045
    TMV-IN-6

    		TMV Infection
    TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent. TMV-IN-6 inhibits virus assembly by binding totobacco mosaic virus (TMV) CP and interfere with the assembly process of TMV CP and RNA .
    TMV-IN-6
  • HY-155044
    TMV-IN-5

    		TMV Fungal Infection
    TMV-IN-5 (compound 1a) is an anti-plant virus/fungal agent. TMV-IN-5 inhibits viral assembly by binding to tobacco mosaic virus (TMV) CP. TMV-IN-5 can be used in the development of pesticides .
    TMV-IN-5
  • HY-148567
    TMV-IN-1

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor .
    TMV-IN-1
  • HY-163201
    TMV-IN-7

    		TMV Infection
    TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly .
    TMV-IN-7
  • HY-163754
    TMV-IN-9

    		TMV Infection
    TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host .
    TMV-IN-9
  • HY-N13047
    Ningnanmycin

    		Others Infection
    Ningnanmycin is a plant antiviral agent that has been found to directly bind to the coat protein (CP) of tobacco mosaic virus (TMV) and inhibit its assembly process. These interactions lead to the dissociation of the coat protein from the discoid structure into monomers，significantly reducing the pathogenicity of TMV .
    Ningnanmycin
  • HY-N15076
    Herbimycin B

    		Src Antibiotic Bacterial Infection Cancer
    Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells .
    Herbimycin B
  • HY-N12249
    7-Deoxy-trans-dihydronarciclasine

    		Amyloid-β TMV Infection Neurological Disease Inflammation/Immunology
    7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .
    7-Deoxy-trans-dihydronarciclasine
  • HY-121255
    (-)-Cryptopleurine

    (R)-Cryptopleurine; NSC 19912

    		 TMV Cancer
    (–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
    (-)-Cryptopleurine
  • HY-117085
    Lobaric acid

    		Phosphatase TMV Lipoxygenase Cancer
    Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC50=97.9 μM) and inhibits cancer cell proliferation (EC50 of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC50=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).
    Lobaric acid

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