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Isoforms Recommended: TEAD
Results for "

TEAD3

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134956
    VT104
    1 Publications Verification

    		 YAP Cancer
    VT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer .
    VT104
  • HY-147208
    MSC-4106

    		YAP Cancer
    MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model .
    MSC-4106
  • HY-147136
    MYF-03-176

    		YAP Cancer
    MYF-03-176 is an orally active inhibitor of TEAD, and suppresses TEAD transcriptional activity with an IC50 of 11 nM. The IC50 values of MYF-03-176 for TEAD1, TEAD3, and TEAD4 are 47, 32, and 71 nM, respectively. MYF-03-176 inhibits hippo signaling defective malignant pleural mesothelioma (MPM) cells. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model [3].
    MYF-03-176
  • HY-RS24777
    Tead3 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Tead3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tead3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tead3 Rat Pre-designed siRNA Set A
    Tead3 Rat Pre-designed siRNA Set A
  • HY-RS14344
    TEAD3 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TEAD3 Human Pre-designed siRNA Set A contains three designed siRNAs for TEAD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TEAD3 Human Pre-designed siRNA Set A
    TEAD3 Human Pre-designed siRNA Set A
  • HY-RS18299
    Tead3 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Tead3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tead3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tead3 Mouse Pre-designed siRNA Set A
    Tead3 Mouse Pre-designed siRNA Set A
  • HY-170764
    M3686

    		YAP Cancer
    M3686 (Compound 29) is a potent, selective TEAD1 inhibitor with an IC50 value of 51 nM. M3686 also shows weaker binding activity on TEAD3. M3686 potently inhibits cell viability against YAP-dependent NCI-H226 cell line with an IC50 value of 0.06 uM. M3686 shows strong anti-tumor effects in the NCI-H226 xenograft model .
    M3686
  • HY-161568
    TEAD-IN-10

    		YAP Cancer
    TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research .
    TEAD-IN-10
  • HY-161569
    TEAD-IN-11

    		YAP Cancer
    TEAD-IN-11 (compound 38) has a good inhibitory effect on TEAD1 (IC50=8.7 nM), TEAD2 (IC50=3.4 nM), TEAD3 (IC50=5.6 nnM). TEAD-IN-11 has good selective activity against TEAD1-3 as a covalent inhibitor. TEAD-IN-11 can be used for cancer research .
    TEAD-IN-11
  • HY-173139
    TEAD-IN-19

    		YAP Cancer
    TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, exhibiting inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% against TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at a concentration of 10 μM. TEAD-IN-19 shows potent anti-proliferative and anti-migratory activities in prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds promise for research in the field of cancer therapy .
    TEAD-IN-19
  • HY-172113
    H122

    		PROTACs YAP c-Myc Cancer
    H122 is a PROTAC degrader for TEAD that degrades TEAD1 with a DC50 of 3 nM, and exhibits good affinity to TEAD2, TEAD3, and TEAD4 with Ki of 2.0, 3.6 and 1.6 nM. H122 downregulates the expression of Myc. H122 inhibits the cell growth of MSTO-211H and NCI-H226 with IC50 of 21.3 nM and 0.6 nM, and exhibits antitumor efficacy in mouse models . (Pink: ligand for target protein (HY-151525); Black: linker (HY-W573128); Blue: ligand for E3 ligase Cereblon (HY-W087383))
    H122

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