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TDP1-IN-4

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175779
    TDP1-IN-4

    		Phosphodiesterase (PDE) Cancer
    TDP1-IN-4 (Compound 33) is a Tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 0.90  μM. TDP1-IN-4 has a strong synergistic effect with Camptothecin (HY-16560) in SK-Mel-2 cells, but not in cancer cells (A549, HCT-116 and MCF-7 cells) and non-cancerous Ges-1 cells. TDP1-IN-4 can be used for cancer chemotherapy and radiotherapy research .
    TDP1-IN-4

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