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Isoforms Recommended: T1R3
Results for "

T1R3

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Natural
Products

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139091

    Taste Receptor Others
    FEMA 4774 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer .
    FEMA 4774
  • HY-W030796A

    Taste Receptor Metabolic Disease
    Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole inhibits insulin secretion induced by glucose in mouse islets .
    Lactisole
  • HY-W030796

    Taste Receptor Metabolic Disease
    Lactisole free acid is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit, a glucose-sensing receptor. Lactisole free acid inhibits insulin secretion induced by glucose in mouse islets .
    Lactisole free acid
  • HY-N2541

    Taste Receptor mTOR Autophagy Apoptosis Metabolic Disease
    Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR .
    Gymnemic acid I
  • HY-122351A

    Taste Receptor Others
    Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame
  • HY-122351

    Drug Derivative Taste Receptor Others
    Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame free acid
  • HY-122351AR

    Reference Standards Taste Receptor Others
    Advantame (Standard) is the analytical standard of Advantame. This product is intended for research and analytical applications. Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame (Standard)
  • HY-RS14214

    Small Interfering RNA (siRNA) Others

    TAS1R3 Human Pre-designed siRNA Set A contains three designed siRNAs for TAS1R3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TAS1R3 Human Pre-designed siRNA Set A
    TAS1R3 Human Pre-designed siRNA Set A
  • HY-RS27720

    Small Interfering RNA (siRNA) Others
    Tas1r3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tas1r3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Tas1r3 Rat Pre-designed siRNA Set A
    Tas1r3 Rat Pre-designed siRNA Set A
  • HY-RS21204

    Small Interfering RNA (siRNA) Others

    Tas1r3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tas1r3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tas1r3 Mouse Pre-designed siRNA Set A
    Tas1r3 Mouse Pre-designed siRNA Set A

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