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Isoforms Recommended: T1R1
Results for "

T1R2

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Natural
Products

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139091
    FEMA 4774

    		Taste Receptor Others
    FEMA 4774 is a positive allosteric modulator of taste receptors T1R2 and T1R3, two subunits of the human sweet taste receptor. FEMA 4774 is also used as a sucrose sweetness enhancer .
    FEMA 4774
  • HY-N2541
    Gymnemic acid I

    		Taste Receptor mTOR Autophagy Apoptosis Metabolic Disease
    Gymnemic acid I is a bioactive triterpene saponin found in Gymnema sylvestre. Gymnemic acid I is an antisweetness inhibitor via human sweet receptor type 1 receptor 2 (T1R2) and T1R3. Gymnemic acid I is a ribosomal protein biosynthesis inhibitor. Gymnemic acid I has antidiabetic effects. Gymnema acid I induces autophagy-protected MIN-6 cells from apoptosis under high glucose stress by inhibiting the phosphorylation activity of mTOR .
    Gymnemic acid I
  • HY-122351A
    Advantame

    		Taste Receptor Others
    Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame
  • HY-B1390A
    Saccharin sodium

    		Bacterial Infection
    Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .
    Saccharin sodium
  • HY-122351
    Advantame free acid

    		Drug Derivative Taste Receptor Others
    Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame free acid
  • HY-122351AR
    Advantame (Standard)

    		Reference Standards Taste Receptor Others
    Advantame (Standard) is the analytical standard of Advantame. This product is intended for research and analytical applications. Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K + channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits .
    Advantame (Standard)
  • HY-B1390AR
    Saccharin sodium (Standard)

    		Bacterial Reference Standards Infection
    Saccharin (sodium) (Standard) is the analytical standard of Saccharin (sodium). This product is intended for research and analytical applications. Saccharin sodium is an orally active, non-caloric artificial sweetener (NAS). Saccharin sodium has bacteriostatic and microbiome-modulating properties. Saccharin binds to and signals via specific taste receptors, not only in the oral cavity but also alongside the gastrointestinal tract. Saccharin has been reported to bind the human and rodent heteromeric guanine nucleotide-binding protein (G protein) coupled sweet taste receptors T1R2/T2R3 as well as the human bitter taste receptor T2R43 and T2R44. Saccharin can inhibit bacterial growth in vitro .
    Saccharin sodium (Standard)
  • HY-RS14213
    TAS1R2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TAS1R2 Human Pre-designed siRNA Set A contains three designed siRNAs for TAS1R2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TAS1R2 Human Pre-designed siRNA Set A
    TAS1R2 Human Pre-designed siRNA Set A
  • HY-RS21953
    Tas1r2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Tas1r2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tas1r2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tas1r2 Mouse Pre-designed siRNA Set A
    Tas1r2 Mouse Pre-designed siRNA Set A
  • HY-RS28470
    Tas1r2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    Tas1r2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tas1r2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Tas1r2 Rat Pre-designed siRNA Set A
    Tas1r2 Rat Pre-designed siRNA Set A

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