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Results for "

Status epilepticus

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121877
    Valnoctamide
    1 Publications Verification

    Valmethamide

    		 GABA Receptor Neurological Disease
    Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors .
    Valnoctamide
  • HY-103232
    IEM-1925 bromide

    		mGluR Neurological Disease
    IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
    IEM-1925 bromide
  • HY-129105
    Clomethiazole
    3 Publications Verification

    		 GABA Receptor Cytochrome P450 Neurological Disease
    Chlormethiazole is an potent and orally active GABAA agonist . Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus .
    Clomethiazole
  • HY-A0296
    Chlormethiazole hydrochloride
    3 Publications Verification

    Clomethiazole hydrochloride

    		 Cytochrome P450 Neurological Disease
    Clomethiazole hydrochloride is a potent and orally active GABAA agonist . Clomethiazole hydrochloride inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Clomethiazole hydrochloride is an anticonvulsant agent and has the potential for treating convulsive status epilepticus .
    Chlormethiazole hydrochloride
  • HY-138668
    JW-65

    		TRP Channel Cancer
    JW-65 (compound 20) is a TRPC3 inhibitor. JW-65 can be used in neurological and cardiovascular disease related research .
    JW-65
  • HY-175251
    GABAA receptor modulator-9

    		GABA Receptor Neurological Disease
    GABAA receptor modulator-9 is and positive allosteric modulator of a1β2y2 subtype GABAA that can cross the blood-brain barrier. GABAA receptor modulator-9 exhibits comparable activity on α1β2γ2 (EC50: 0.9 μM in oocytes, 0.2 μM in CHO cells) and on α1β2, α3β2γ2 and α1β3γ2 (EC50s of 1.3, 3.4 and 1.1 μM). GABAA receptor modulator-9 significantly suppresses seizure progression and reduces delayed mortality. GABAA receptor modulator-9 can be used for the study of status epilepticus (SE) .
    GABAA receptor modulator-9
  • HY-121877S
    Valnoctamide-d5

    		Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Valnoctamide-d5 is the deuterium labeled Valnoctamide. Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors .
    Valnoctamide-d5
  • HY-121877R
    Valnoctamide (Standard)

    		GABA Receptor Neurological Disease
    Valnoctamide (Standard) is the analytical standard of Valnoctamide. This product is intended for research and analytical applications. Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors .
    Valnoctamide (Standard)
  • HY-129105R
    Clomethiazole (Standard)

    		GABA Receptor Cytochrome P450 Neurological Disease
    Clomethiazole (Standard) is the analytical standard of Clomethiazole. This product is intended for research and analytical applications. Chlormethiazole is an potent and orally active GABAA agonist . Chlormethiazole inhibits cytochrome P450 isoforms: CYP2A6 and CYP2E1 in human liver microsomes. Chlormethiazole is an anticonvulsant agent and has the potential for treating convulsive status epilepticus .
    Clomethiazole (Standard)

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