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Results for "

Siderophores

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

2

Peptides

17

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123648

    Biochemical Assay Reagents Others
    Rhizoferrin is a siderophore, which can be isolated from Rhizopus microsporus. Rhizoferrin binds iron ions with high affinity, and can be used as an effective iron source .
    Rhizoferrin
  • HY-122280

    Endogenous Metabolite Infection
    Aerobactin is a siderophore produced by bacteria. Aerobactin is a highly potent pathogenic factor .
    Aerobactin
  • HY-N11874

    Bacterial Infection
    Staphyloferrin A is a siderophore protein that can be combined with antibiotics to study drug-resistant bacteria that cause skin diseases .
    Staphyloferrin A
  • HY-124236

    Bacterial Others
    Chrysobactin is a compound isolated from the plant pathogenic bacterium Erwinia chrysanthemi. Chrysobactin has siderophore activity .
    Chrysobactin
  • HY-128525R

    Bacterial Reference Standards Reactive Oxygen Species (ROS) Infection Inflammation/Immunology
    Enterobactin (Standard) is the analytical standard of Enterobactin. This product is intended for research and analytical applications. Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals .
    Enterobactin (Standard)
  • HY-N15176

    DNA/RNA Synthesis Cancer
    Bisucaberin is a natural siderophore, is a DNA synthesis inhibitor. Bisucaberin shows cytostasis for tumor cells. Bisucaberin sensitizes tumor cells to macrophage-mediated cytolysis .
    Bisucaberin
  • HY-122395

    Endogenous Metabolite Cancer
    Triornicin is a siderophore. Triornicin can be used in cancer research .
    Triornicin
  • HY-N14935

    Biochemical Assay Reagents Infection
    Agrobactin is a catechol-type siderophore (microbial iron transport compound) .
    Agrobactin
  • HY-N13871

    Antibiotic Bacterial Infection
    Anguibactin is an antibiotic that acts as a siderophore. Anguibactin has a strong affinity with Fe 3+ .
    Anguibactin
  • HY-118009

    ISD-I 207

    Biochemical Assay Reagents Others
    Azotochelin (ISD-I 207) is a biscatecholate siderophore found in the strain of Azotobacter vinelandii .
    Azotochelin
  • HY-139887

    Bacterial Infection
    Antibacterial agent 63, a conjugate of aztreonam to a siderophore mimetic, shows activity against gram-negative bacteria.
    Antibacterial agent 63
  • HY-132915

    Bacterial Infection
    Anti gram-positive/negative bacteria agent 1 is an antibiotic conjugate with an artificial MECAM-based siderophore.
    Anti gram-positive/negative bacteria agent 1
  • HY-129580

    Bacterial Fungal Infection
    Nannochelin B is a novel citrate-hydroxamate siderophore with a growth-inhibitory activity against some bacteria and fungi .
    Nannochelin B
  • HY-172023

    Bacterial Infection
    apo-Enterobactin is a derivative of Enterobactin (HY-128525). Enterobactin is a bacterial siderophore that promotes iron absorption .
    apo-Enterobactin
  • HY-N14943

    Bacterial Infection
    Pseudoalterobactin A is a siderophore found in Pseudoalteromonas sp.KP20-R. Pseudoalterobactin A has a strong affinity for iron ions .
    Pseudoalterobactin A
  • HY-159969

    Bacterial Antibiotic Infection
    MLEB-22043 is a synthetic siderophore-monobactam conjugate that is taken up into bacteria via its synthetic siderophore component by TonB-dependent transporters. Once inside the bacteria, it exerts antibacterial activity through its β-lactam component. MLEB-22043 is a broad-spectrum antibiotic with significant inhibitory activity against Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa .
    MLEB-22043
  • HY-117738

    Others Others
    Benarthin is a catechol-type siderophore isolated from the marine actinomycete Streptomyces YM5-799 that exhibits iron-chelating properties .
    Benarthin
  • HY-113379

    Tyrosinase Infection
    2,3-Diaminopropionic acid is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid is the inhibitor for polyphenoloxidase (PPO) .
    2,3-Diaminopropionic acid
  • HY-W013673

    Tyrosinase Infection
    2,3-Diaminopropionic acid hydrochloride is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid hydrochloride is the inhibitor for polyphenoloxidase (PPO) .
    2,3-Diaminopropionic acid hydrochloride
  • HY-N14944

    Bacterial Infection
    Pseudoalterobactin B is a siderophore found in Pseudoalteromonas sp.KP20-R. Pseudoalterobactin B has a strong affinity for iron ions .
    Pseudoalterobactin B
  • HY-139698

    LCB10-0200

    Antibiotic Bacterial Infection
    GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.
    GT-1
  • HY-17628
    Cefiderocol
    10+ Cited Publications

    S-649266

    Bacterial Antibiotic Infection
    Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
    Cefiderocol
  • HY-163383

    L-EOP

    Bacterial Infection
    L-Ent-oxPt IV (L-EOP) is a Oxaliplatin (HY-17371)-based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage .
    L-Ent-oxPt(IV)
  • HY-135498

    Bacterial Infection
    Ferrioxamine E is a bacterial siderophore produced by a variety of bacteria including S. glaucescens, M. luteus, and P. mendocina. Ferrioxamines, including ferrioxamine E, are the sole iron source for Salmonella, and have been used as growth enriching agents in the detection of Salmonella in food and industrial applications.
    Ferrioxamine E
  • HY-19882

    Bacterial Infection
    BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively .
    BAL-30072
  • HY-122280R

    Reference Standards Endogenous Metabolite Infection
    Calcium gluconate (Standard) is the analytical standard of Calcium gluconate. This product is intended for research and analytical applications. Calcium Gluconate Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Aerobactin (Standard)
  • HY-151944

    Bacterial Antibiotic Infection
    Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (Ciprofloxacin (HY-B0356)) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) .
    Antibacterial agent 128
  • HY-17628S1

    S-649266-d6

    Isotope-Labeled Compounds Antibiotic Bacterial Infection
    Cefiderocol-d6 (S-649266-d6) is a deuterated labeled Cefiderocol (HY-17628). Cefiderocol is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less .
    Cefiderocol-d6
  • HY-128525

    Bacterial Reactive Oxygen Species (ROS) Infection Inflammation/Immunology
    Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals .
    Enterobactin
  • HY-124237

    Bacterial Others
    N-Octanoyl-DL-homoserine lactone is a member of N-acyl homoserine lactones (AHLs) family, also one of the signal molecule of quorum-sensing (QS) signals. N-Octanoyl-DL-homoserine lactone can regulate the production of siderophores and present positive correlation in Aeromonas sobria strain AS7. N-Octanoyl-DL-homoserine lactone can also regulate the secretion of proteases and stimulate the production of total volatile basic nitrogen (TVB-N) .
    N-Octanoyl-DL-homoserine lactone
  • HY-P1997

    Desferrichrome; DFC; N-Desferriferrichrome

    Biochemical Assay Reagents Others
    Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
    Ferrichrome Iron-free
  • HY-157433

    Bacterial Infection
    Mab-SaS-IN-1 (compoud 1H) is Mab-SaS inhibitor with the IC50 of 2 μM. Mab-SaS-IN-1 can be used for study of antibiosis by blocking iron uptake and metabolism .
    Mab-SaS-IN-1

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