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Results for "

STR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (8) Bacterial (12) Bcl-2 Family (1) Cholecystokinin Receptor (1) Fungal (2) HDAC (1)
By Research Areas:	Cancer (6) Infection (13) Neurological Disease (4)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14855A

(S)-Tedizolid 2 Publications Verification (S)-TR 700; (S)-DA 7157	Bacterial Antibiotic	Infection
(S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.

HY-B1906

Streptomycin Maximum Cited Publications 32 Publications Verification Agrept; Agrimycin; STReptomycin A	Antibiotic Bacterial	Infection Neurological Disease
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .

HY-112416

AZD4320 2 Publications Verification	Bcl-2 Family	Cancer
AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC₅₀s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively.

HY-161412

STR-V-53	HDAC	Cancer
STR-V-53 is an HDAC inhibitor (IC₅₀ in nM).STR-V-53 increases histone acetylation in tumor cells by inhibiting the activity of these enzymes, which in turn regulates gene expression.STR-V-53 inhibits tumor growth, and induces apoptosis .

HY-14855AR

(S)-Tedizolid (Standard) (S)-TR 700 (Standard); (S)-DA 7157 (Standard)	Bacterial Antibiotic	Infection
(S)-Tedizolid (Standard) is the analytical standard of (S)-Tedizolid. This product is intended for research and analytical applications. (S)-Tedizolid is the S-enantiomer of Tedizolid. Tedizolid is a novel oxazolidinone with activity against Gram-positive pathogens. (S)-Tedizolid is the less active isomer.

HY-B1906R

Streptomycin (Standard)	Antibiotic Bacterial	Infection Neurological Disease
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .

HY-N15072

Naphthomycinol	Others	Neurological Disease
Naphthomycinol is a neuroprotective agent found in Str. sp. PF7 .

HY-N14885

Pyridindolol K1	Antibiotic Bacterial	Infection
Pyridindolol K1 is an alkaloid antibiotic found in Str. Sp. K93-0711 .

HY-N14817

Neocopiamycin B	Fungal	Infection
Neocopiamycin B is found in the strain of Str. hygroscopicus var. crystallogenes. Neocopiamycin B has antifungal activity .

HY-N14381

Leptofuranin A	Others	Cancer
Leptofuranin A is found in the strain of Str. tanashiensis. Leptofuranin A causes the stagnation of normal cells, but it can cause the death of transformed cells .

HY-N14314

Norplicacetin	Bacterial	Infection
Norplicacetin is originally found in Str. plicatus NCIB 11305. Norplicacetin has the effect of anti-Gram-positive bacteria and mycobacterium .

HY-N14384

Leptofuranin D	Others	Cancer
Leptofuranin D is found in the strain of Str. tanashiensis. Leptofuranin D causes the stagnation of normal cells, but it can cause the death of transformed cells .

HY-N14191

Malonylniphimycin	Antibiotic Bacterial Fungal	Infection
Malonylniphimycin is a macrolide antibiotic found in Streptomyces str. hygroscopicus B-7. Malonylniphimycin is resistant to Gram-positive bacteria, fungi and yeasts .

HY-N14383

Leptofuranin C	Others	Cancer
Leptofuranin C is found in the strain of Str. tanashiensis. Leptofuranin C causes the stagnation of normal cells, but it can cause the death of transformed cells .

HY-N14382

Leptofuranin B	Others	Cancer
Leptofuranin B is found in the strain of Str. tanashiensis. Leptofuranin B causes the stagnation of normal cells, but it can cause the death of transformed cells .

HY-111019A

SCH 34343 sodium	Antibiotic Bacterial	Infection
SCH 34343 sodium is a potent β-lactam Antibiotic with bactericidal activity against Streptococcus pneumoniae, viridans streptococci, streptococci of groups A, B, C and G, and Str. bovis .

HY-N14886

Pyridindolol K2	Antibiotic Bacterial	Infection
Pyridindolol K2 is an alkaloid antibiotic found in Str. Sp. K93-0711. Pyridindolol K2 can inhibit the adhesion of HL-60 cells .

HY-30263

4-Heptyloxyphenol p-(Heptyloxy)phenol	Bacterial	Infection
4-Heptyloxyphenol (p-(heptyloxy)phenol) has antibacterial activity agaisnt P. gingivalis, S. artemidis, Str. sobrinus (MIC: 0.10, 0.21, 0.14 mM) .

HY-101352

LY 225910	Cholecystokinin Receptor	Neurological Disease
LY 225910 is a selective antagonist for cholecystokinin receptor (CCK2 receptor), which affects the excitatory response to morphine, and leads to morphine sensitization .

HY-N14924

Oganomycin GA	Bacterial	Infection
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .

HY-N14926

Oganomycin GB	Bacterial	Infection
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .

Streptomycin 30+ Cited Publications Agrept; Agrimycin; STReptomycin A	Microorganisms Source classification	Antibiotic Bacterial
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .

Streptomycin (Standard)	Microorganisms Source classification	Antibiotic Bacterial
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .

Naphthomycinol	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Others
Naphthomycinol is a neuroprotective agent found in Str. sp. PF7 .

Pyridindolol K1	Structural Classification Alkaloids Microorganisms Source classification Pyridine Alkaloids	Antibiotic Bacterial
Pyridindolol K1 is an alkaloid antibiotic found in Str. Sp. K93-0711 .

Neocopiamycin B	Structural Classification Natural Products Microorganisms Source classification	Fungal
Neocopiamycin B is found in the strain of Str. hygroscopicus var. crystallogenes. Neocopiamycin B has antifungal activity .

Leptofuranin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Leptofuranin A is found in the strain of Str. tanashiensis. Leptofuranin A causes the stagnation of normal cells, but it can cause the death of transformed cells .

Norplicacetin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Norplicacetin is originally found in Str. plicatus NCIB 11305. Norplicacetin has the effect of anti-Gram-positive bacteria and mycobacterium .

Leptofuranin D	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Leptofuranin D is found in the strain of Str. tanashiensis. Leptofuranin D causes the stagnation of normal cells, but it can cause the death of transformed cells .

Malonylniphimycin	Structural Classification Microorganisms Antibiotics Cyclopeptides Source classification	Antibiotic Bacterial Fungal
Malonylniphimycin is a macrolide antibiotic found in Streptomyces str. hygroscopicus B-7. Malonylniphimycin is resistant to Gram-positive bacteria, fungi and yeasts .

Leptofuranin C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Leptofuranin C is found in the strain of Str. tanashiensis. Leptofuranin C causes the stagnation of normal cells, but it can cause the death of transformed cells .

Leptofuranin B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Others
Leptofuranin B is found in the strain of Str. tanashiensis. Leptofuranin B causes the stagnation of normal cells, but it can cause the death of transformed cells .

Pyridindolol K2	Structural Classification Alkaloids Microorganisms Source classification Pyridine Alkaloids	Antibiotic Bacterial
Pyridindolol K2 is an alkaloid antibiotic found in Str. Sp. K93-0711. Pyridindolol K2 can inhibit the adhesion of HL-60 cells .

Oganomycin GA	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Oganomycin GA is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria .

Oganomycin GB	Structural Classification Natural Products Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Oganomycin GB is Streptomyces str. oganonensis Y-G 19Z and Oganomycin A is produced when p-hydroxycinnamate sodium salt is added to the fermentation medium. Under the action of D-amino acid oxidase, A generates glutaryl derivative, GA; A and GA were converted to B and GB by acid hydrolysis to remove sulfate esters. The effect of B on d-amino acid oxidase was also changed to GB. A and B were more stable than A and B of cemycin, and had stronger effect against Gram-positive and Gram-negative bacteria than Gram-positive bacteria. The antibacterial activity of A and B was higher than that of GA and GB .

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