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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

STEAP1 Antibody

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Inhibitory Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P990673
    Vandortuzumab

    DSTP-3086S Antibody; RG-7450 Antibody

    		 Transmembrane Glycoprotein Inflammation/Immunology
    Vandortuzumab is a CHO-expressed humanized antibody targeting STEAP1. Vandortuzumab has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 148.74 kDa. The isotype control for Vandortuzumab can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
    Vandortuzumab
  • HY-138633
    PROTAC BRD4 Degrader-10

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively .
    PROTAC BRD4 Degrader-10
  • HY-P990688
    Xaluritamig

    AMG-509

    		 CD3 Inflammation/Immunology Cancer
    Xaluritamig (AMG-509) is a humanized bi-specific antibody targeting STEAP1 and CD3. Xaluritamig consists of two STEAP1 binding domains, a CD3e binding fragment variable domain and an Fc domain to prevent effector function. Xaluritamig binds T cells to facilitate T cell-mediated lysis. Xaluritamig can be used for the study of STEAP1-expressing prostate cancer and Ewing sarcoma .
    Xaluritamig
  • HY-138635
    PROTAC BRD4 Degrader-12

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively .
    PROTAC BRD4 Degrader-12
  • HY-138634
    GNE-987 GSH linker-2

    		PROTAC-Linker Conjugates for PAC Epigenetic Reader Domain Cancer
    GNE-987 GSH linker-2 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 GSH linker-2 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively .
    GNE-987 GSH linker-2
  • HY-138632
    PROTAC BRD4 Degrader-9

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC BRD4 Degrader-9 (compound 8a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively .
    PROTAC BRD4 Degrader-9

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