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Results for "

SRF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) CCR (1) CD47 (1) Interleukin Related (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) NTPDase (1) Ras (9) ROCK (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118748

Suprafenacine SRF	Microtubule/Tubulin	Cancer
Suprafenacine is a cell permeable, tubulin-destabilizing molecule which bind microtubules at the colchicine-binding site and inhibit polymerization. Suprafenacine can induce G2/M cell cycle arrest and apoptosis, and can be used for cancer research .

HY-P990024

Casdozokitug SRF-388	Interleukin Related	Cancer
Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 .

HY-P99533

Urabrelimab 1 Publications Verification SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P990068

Perenostobart SRF617	NTPDase	Inflammation/Immunology Cancer
Perenostobart (SRF617) is a human IgG4 antibody with inhibitory activity against CD39 ATPase. Perenostobart inhibits CD39-mediated hydrolysis of extracellular ATP to AMP, with IC₅₀ values of 1.9 nM (HEK293 OE cells), 0.7 nM (MOLP-8 cells), and 1.2 nM (RBC-lysed whole blood). Perenostobart enhances CD4 ⁺ T-cell proliferation, promotes dendritic cell maturation, and boosts inflammasome activation in macrophages in the presence of ATP. Perenostobart demonstrates significant single-agent anti-tumor efficacy in MOLP-8 and H520 xenograft models. Perenostobart can be used for the study of cancer .

HY-153078

*MRTF/SRF-IN-1*	Ras	Cancer
MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis .

HY-120855

CCG-100602 2 Publications Verification	Ras	Cardiovascular Disease
CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF .

HY-RS13760

SRF Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SRF Human Pre-designed siRNA Set A contains three designed siRNAs for SRF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SRF Human Pre-designed siRNA Set A SRF Human Pre-designed siRNA Set A

HY-RS17529

Srf Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Srf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Srf Mouse Pre-designed siRNA Set A Srf Mouse Pre-designed siRNA Set A

HY-RS23985

Srf Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Srf Rat Pre-designed siRNA Set A contains three designed siRNAs for Srf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Srf Rat Pre-designed siRNA Set A Srf Rat Pre-designed siRNA Set A

HY-P991061

Tagmokitug CHS-114; SRF-114	CCR	Cancer
Tagmokitug (CHS-114) is a fully human IgG1 antibody that targets CCR8. Tagmokitug has the potential for the study of head and neck squamous cell carcinoma (HNSCC). The isotype control for Tagmokitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-108361

CCG-203971 1 Publications Verification	Ras	Inflammation/Immunology Cancer
CCG-203971 is a second-generation *Rho/MRTF/SRF* pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC₅₀ =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC₅₀ of 4.2 μM. Potential anti-metastasis Agent .

HY-130011

CCG-232964	ROCK Ras	Neurological Disease Cancer
CCG-232964 is an orally active inhibitor of *Rho/MRTF/SRF*. CCG-232964 inhibits LPA-induced CTGF gene expression .

HY-13991

CCG-1423 Maximum Cited Publications 13 Publications Verification	Ras Apoptosis	Cancer
CCG-1423 is an inhibitor of *Rho/MRTF/SRF* pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes .

HY-111432

CCG-232601	Ras	Others
CCG-232601 (compound 8f) is a potent and orally active *Rho/MRTF/SRF* transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma .

HY-13991R

CCG-1423 (Standard)	Ras Apoptosis	Cancer
CCG-1423 (Standard) is the analytical standard of CCG-1423. This product is intended for research and analytical applications. CCG-1423 is an inhibitor of Rho/MRTF/SRF pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes .

HY-162904

BPU17	Mitochondrial Metabolism	Cardiovascular Disease
BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent .

HY-162968

MRTF-A-IN-1	Ras	Cardiovascular Disease Metabolic Disease
MRTF-A-in-1 (Compound 14) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging .

HY-162969

MRTF-A-IN-2	Ras	Cardiovascular Disease Metabolic Disease
MRTF-A-in-2 (Compound 16) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging .

Cat. No.	Product Name	Target	Research Area

HY-P990024

Casdozokitug SRF-388	Interleukin Related	Cancer
Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 .

HY-P99533

Urabrelimab 1 Publications Verification SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P990068

Perenostobart SRF617	NTPDase	Inflammation/Immunology Cancer
Perenostobart (SRF617) is a human IgG4 antibody with inhibitory activity against CD39 ATPase. Perenostobart inhibits CD39-mediated hydrolysis of extracellular ATP to AMP, with IC₅₀ values of 1.9 nM (HEK293 OE cells), 0.7 nM (MOLP-8 cells), and 1.2 nM (RBC-lysed whole blood). Perenostobart enhances CD4 ⁺ T-cell proliferation, promotes dendritic cell maturation, and boosts inflammasome activation in macrophages in the presence of ATP. Perenostobart demonstrates significant single-agent anti-tumor efficacy in MOLP-8 and H520 xenograft models. Perenostobart can be used for the study of cancer .

HY-P991061

Tagmokitug CHS-114; SRF-114	CCR	Cancer
Tagmokitug (CHS-114) is a fully human IgG1 antibody that targets CCR8. Tagmokitug has the potential for the study of head and neck squamous cell carcinoma (HNSCC). The isotype control for Tagmokitug can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Compare	Product Name	Species	Source

HY-P71821

	PTK7 Protein, Human (P.pastoris, His) CCK 4; CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; Tyrosine-protein kinase-like 7	Human	P. pastoris
	The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Human (P.pastoris, His) is the recombinant human-derived PTK7 protein, expressed by P. pastoris , with N-6*His labeled tag.

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HY-P87085

	SRF Antibody (YA6778) c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; Serum response factor antibody; SRF antibody; c fos serum response element binding factor antibody; c fos serum response element binding transcription factor antibody; ELK3 antibody; ERP antibody; MCM 1 antibody; MCM1 antibody; OTTHUMP00000039820 antibody; SAP2 antibody; Serum response factor antibody; SRF antibody; SRF serum response factor c fos serum response element binding transcription factor antibody; SRF_HUMAN antibody;	WB, ICC/IF, IHC-P, FC, IP	Human, Mouse, Rat
	SRF Antibody (YA6778) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SRF.

HY-P83523

	General Transcription Factor II I Antibody (YA3268) GTF2I; BAP135; WBSCR6; General transcription factor II-I; GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BAP-135; BTK-associated protein 135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome chromosomal region	WB, IHC-F, IHC-P, ICC/IF	Human
	General Transcription Factor II I Antibody (YA3268) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to General Transcription Factor II I.

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SRF Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SRF Human Pre-designed siRNA Set A contains three designed siRNAs for SRF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Srf Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Srf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Srf Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Srf Rat Pre-designed siRNA Set A contains three designed siRNAs for Srf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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