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Results for "

SPT

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125351
    SPT-IN-1
    1 Publications Verification

    		 Ceramidase Metabolic Disease
    SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research .
    SPT-IN-1
  • HY-170794
    ALT-007

    		Acyltransferase Ceramidase Metabolic Disease
    ALT-007 is an orally active serine palmitoyltransferase (SPT) inhibitor that selectively reduces the levels of toxic very-long-chain deoxysphingolipids to enhance protein homeostasis. ALT-007 restores aging-related loss of muscle mass in a mouse model of sarcopenia. ALT-007 enhances protein homeostasis in both mouse and C. elegans models of aging and disease. ALT-007 can be used for age-related neuromuscular diseases research .
    ALT-007
  • HY-158009
    SGF29-IN-1

    		Others Cancer
    SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)–associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia .
    SGF29-IN-1
  • HY-115498
    ARN14494

    		Apoptosis NO Synthase Interleukin Related COX Neurological Disease Inflammation/Immunology
    ARN14494 is a potent and selective serine palmitoyltransferase (SPT) inhibitor, with an IC50 of 27.3 nM. ARN14494 affects the CNS in terms of anti-inflammation and neuroprotection. ARN14494 protects neurons from β-amyloid 1-42-induced neurotoxicity through a variety of mechanisms, including anti-oxidation, anti-apoptosis, and anti-inflammation. ARN14494 can be used for Alzheimer’s disease research .
    ARN14494
  • HY-N6798
    Myriocin
    5+ Cited Publications

    Thermozymocidin; ISP-I

    		 HCV Antibiotic Infection
    Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection .
    Myriocin
  • HY-N6798R
    Myriocin (Standard)

    Thermozymocidin (Standard); ISP-I (Standard)

    		 Reference Standards HCV Antibiotic Infection
    Myriocin (Standard) is the analytical standard of Myriocin. This product is intended for research and analytical applications. Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection[1][2][3].
    Myriocin (Standard)
  • HY-RS00473
    AGXT Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    AGXT Human Pre-designed siRNA Set A contains three designed siRNAs for AGXT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    AGXT Human Pre-designed siRNA Set A
    AGXT Human Pre-designed siRNA Set A

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