Search Result
Results for "
SPDP
" in MedChemExpress (MCE) Product Catalog:
28
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-100216
-
SPDP
5 Publications Verification
SPDP Crosslinker; Py-ds-Prp-OSu
|
ADC Linker
|
Cancer
|
|
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
-
- HY-141352
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-W800714
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SPDP-Gly-Gly-methoxy is a linker with SPDP and methyl ester moiety. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions.
|
-
-
- HY-W800711
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.
|
-
-
- HY-W800713
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SPDP-Gly-Pro-acid is a linker with SPDP and carboxylic acid moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
-
- HY-133543
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-133386
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-141354
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG24-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133385
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-133384
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-141353
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-PEG12-acid is a cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-141357
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-126717
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-130195
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-141356
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-124377
-
|
|
PROTAC Linkers
|
Cancer
|
|
SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-141358
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-PEG36-NHS ester is a cleavable 36 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-141123
-
|
|
ADC Linker
|
Cancer
|
|
SPDP-C6-Gly-Leu-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-167333
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-167340
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167335
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167338
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167341
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-167336
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167324
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167331
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167332
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167321
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-167328
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167320
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG2000-SPDP can be used in drug delivery research .
|
-
-
- HY-167327
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167326
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167334
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167318
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167323
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167322
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167339
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA10000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167330
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA2000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG5000-SPDP can be used in drug delivery research .
|
-
-
- HY-167325
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA4000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-167337
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA1000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-167319
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA5000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG3000-SPDP can be used in drug delivery research .
|
-
-
- HY-167329
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLLA3000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG1000-SPDP can be used in drug delivery research .
|
-
-
- HY-W441017
-
|
|
Liposome
|
Others
|
|
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
|
-
-
- HY-126496
-
|
|
ADC Linker
|
Cancer
|
|
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
|
-
-
- HY-126493A
-
-
-
- HY-126497
-
|
|
ADC Linker
|
Cancer
|
|
LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
|
-
-
- HY-126493
-
|
|
Drug-Linker Conjugates for ADC
Microtubule/Tubulin
|
Cancer
|
|
DM4-SPDP is a agent-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody agent conjugate . SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls .
|
-
-
- HY-136309
-
|
|
ADC Linker
|
Cancer
|
|
Ald-PEG23-SPDP is a cleavable 23 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-126495
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-LC-SPDP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.
|
-
-
- HY-126495A
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-140138
-
|
|
ADC Linker
|
Cancer
|
|
PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W440901
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
|
-
- HY-W440900
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-SPDP, MW 3400 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs ( Reagent grade, for research use only.
|
-
- HY-W440899
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-SPDP, MW 1000 is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor. Reagent grade, for research use only.
|
-
- HY-128960
-
-
- HY-W800720
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-2-amino-4-(2-(pyridin-2-yl)disulfanyl)butanoic acid is a small molecule reagent with a 2-thiopyridine linked to a short amino acid. SPDP is a thiol-specific labeling reagent, commonly used in reversibly binding cysteine residues on proteins. The disulfide bond it forms with the cysteine is selectively cleaved in the reducing environment of the cell cytoplasm.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-167333
-
|
|
Drug Delivery
|
|
PLLA2000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167340
-
|
|
Drug Delivery
|
|
PLLA10000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167335
-
|
|
Drug Delivery
|
|
PLLA1000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167338
-
|
|
Drug Delivery
|
|
PLLA10000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167341
-
|
|
Drug Delivery
|
|
PLLA10000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167336
-
|
|
Drug Delivery
|
|
PLLA1000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167324
-
|
|
Drug Delivery
|
|
PLLA4000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167331
-
|
|
Drug Delivery
|
|
PLLA2000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167332
-
|
|
Drug Delivery
|
|
PLLA2000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167321
-
|
|
Drug Delivery
|
|
PLLA5000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167328
-
|
|
Drug Delivery
|
|
PLLA3000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167320
-
|
|
Drug Delivery
|
|
PLLA5000-PEG2000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG2000-SPDP can be used in drug delivery research .
|
-
- HY-167327
-
|
|
Drug Delivery
|
|
PLLA3000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167326
-
|
|
Drug Delivery
|
|
PLLA3000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167334
-
|
|
Drug Delivery
|
|
PLLA1000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167318
-
|
|
Drug Delivery
|
|
PLLA5000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167323
-
|
|
Drug Delivery
|
|
PLLA4000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167322
-
|
|
Drug Delivery
|
|
PLLA4000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167339
-
|
|
Drug Delivery
|
|
PLLA10000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA10000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167330
-
|
|
Drug Delivery
|
|
PLLA2000-PEG5000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA2000-PEG5000-SPDP can be used in drug delivery research .
|
-
- HY-167325
-
|
|
Drug Delivery
|
|
PLLA4000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA4000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167337
-
|
|
Drug Delivery
|
|
PLLA1000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA1000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-167319
-
|
|
Drug Delivery
|
|
PLLA5000-PEG3000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA5000-PEG3000-SPDP can be used in drug delivery research .
|
-
- HY-167329
-
|
|
Drug Delivery
|
|
PLLA3000-PEG1000-SPDP is a polylactic acid derivative that can form micelles in water and the SPDP moiety can react with thiols. PLLA3000-PEG1000-SPDP can be used in drug delivery research .
|
-
- HY-W441017
-
|
|
Drug Delivery
|
|
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
|
-
- HY-W440901
-
|
|
Drug Delivery
|
|
DSPE-PEG-SPDP, MW 5000 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents. The core can encapsulate hydrophilic nutrients, such as protein/peptide and mRNA/DNA/siRNA etc. while the lipid bilayer can solubilize hydrophobic drugs, such as doxorubicin, curcumin etc. The SPDP moiety can react with thiol molecule to form a disulfide bond. Reagent grade, for research use only.
|
-
- HY-W440900
-
|
|
Drug Delivery
|
|
DSPE-PEG-SPDP, MW 3400 is an amphiphilic polyPEG which forms lipid bilayer in water. It can be used to encapsualte therapeutic agents, such as hydrophilic nutrierns (protein/peptide, mRNA/DNA/siRNA) or hdyrophobic drugs ( Reagent grade, for research use only.
|
-
- HY-W440899
-
|
|
Drug Delivery
|
|
DSPE-PEG-SPDP, MW 1000 is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor. Reagent grade, for research use only.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W441017
-
|
|
|
Phospholipids
|
|
DSPE-SPDP is a phospholipid molecule. DSPE-SPDP can orient itself to form lipid bilayer in water. DSPE-SPDP can be used for the research of various biochemical .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
