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SKF38393

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12520A
    SKF 38393 hydrochloride
    Maximum Cited Publications
    18 Publications Verification

    (±)-SKF-38393 hydrochloride; SKF-38393A

    Dopamine Receptor Neurological Disease
    SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
    SKF 38393 hydrochloride
  • HY-12520

    Dopamine Receptor Neurological Disease Cancer
    SKF 38393 is a selective dopamine D1 receptor agonist. SKF 38393 activates the cAMP signaling pathway and promotes dopamine release in the developing rat striatum. SKF 38393 inhibits MCF-7 breast cancer cell proliferation (IC50=0.1 μM). SKF 38393 is promising for research of neurodevelopmental disorders, dopamine-related diseases (e.g., Parkinson’s, dopamine deficiency), and cancers .
    SKF 38393
  • HY-12237

    (±)-SKF-38393 hydrobromide

    Dopamine Receptor Neurological Disease
    SKF 38393 ((±)-SKF-38393) hydrobromide is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
    SKF 38393 hydrobromide
  • HY-12520B

    (±)-SKF-38393 hydrochloride; SKF-38393A hydrochloride

    Dopamine Receptor Potassium Channel Neurological Disease
    (R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel .
    (R)-SKF 38393 hydrochloride
  • HY-12520AR

    Dopamine Receptor Neurological Disease
    SKF 38393 (hydrochloride) (Standard) is the analytical standard of SKF 38393 (hydrochloride). This product is intended for research and analytical applications. SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
    SKF 38393 hydrochloride (Standard)
  • HY-B1752

    LY 171555; (-)-LY 141865

    Dopamine Receptor Neurological Disease
    Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release .
    Quinpirole

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