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Results for "

SEB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Apoptosis (1) Caspase (1) IFNAR (1) MyD88 (1) Small Interfering RNA (siRNA) (2) TNF Receptor (1)
By Research Areas:	Inflammation/Immunology (3) Neurological Disease (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Z-Asp-CH2-DCB	Caspase Apoptosis	Inflammation/Immunology
Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development .

T6167923 10+ Cited Publications	MyD88	Inflammation/Immunology
T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC₅₀s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively .

Adatanserin WY-50324; SEB-324	5-HT Receptor	Neurological Disease
Adatanserin (WY-50324) is a high affinity, selective and partial agonist for the 5-HT_1A receptor with a K_i of 1 nM. Adatanserin is a moderate affinity 5-HT₂ receptor antagonist with a K_i of 73 nM. Adatanserin shows significant anxiolytic and antidepressant activity in an animal conflict model .

Adatanserin hydrochloride WY-50324 hydrochloride; SEB-324 hydrochloride	5-HT Receptor	Neurological Disease
Adatanserin hydrochloride is a high affinity, selective and partial agonist for the 5-HT_1A receptor with a K_i of 1 nM. Adatanserin hydrochloride is a moderate affinity 5-HT₂ receptor antagonist with a K_i of 73 nM. Adatanserin hydrochloride shows significant anxiolytic and antidepressant activity in an animal conflict model .

EM-163	TNF Receptor IFNAR	Inflammation/Immunology
EM-163 is a summative BB-Loop analog. EM-163 can alleviate inflammation and prevent death from toxic shock by targeting the TIR domain of MyD88. EM-163 can be used in the study of SEB poisoning (SEB: Staphylococcal enterotoxin B) .

SETBP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SETBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SETBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SETBP1 Human Pre-designed siRNA Set A SETBP1 Human Pre-designed siRNA Set A

Setbp1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Setbp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Setbp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Setbp1 Mouse Pre-designed siRNA Set A Setbp1 Mouse Pre-designed siRNA Set A

Species:	Human (1) Staphylococcus aureus (1)
Tag:	His (2)
Source:	P. pastoris (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	Enterotoxin type B Protein, S. aureus (P.pastoris, His) 2 Publications Verification entBEnterotoxin type B; SEB	Staphylococcus aureus	P. pastoris
	Enterotoxin B (SEB) is an antigen derived from Staphylococcus aureus (S. aureus) that can be recognized and bound by MHC class II molecules on antigen-presenting cells. Enterotoxin B also interacts with T cell receptors (TCRs), triggering massive activation of CD4+ and CD8+ T cells, leading to the release of proinflammatory cytokines (TNF-α, IFN-γ) and Th2-type cytokines (IL-4, IL-5, IL-13), regulating inflammatory responses. Enterotoxin B also exerts anti-tumor potential in fibrosarcoma models, inducing tumor necrosis. Enterotoxin type B Protein, S. aureus (P.pastoris, His) is a recombinant Enterotoxin B protein expressed by P. pastoris yeast with N-6*His tag.

	RBM38 Protein, Human (His) RNPC1; SEB4	Human	E. coli
	RBM38 Protein, Human (His) is the recombinant human-derived RBM38, expressed by E. coli , with His labeled tag. ,

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SETBP1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SETBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for SETBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Setbp1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Setbp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Setbp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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