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Results for "

Rhamnocitrin

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

4

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1353
    Rhamnocitrin
    1 Publications Verification

    		 p38 MAPK Cardiovascular Disease Inflammation/Immunology
    Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
    Rhamnocitrin
  • HY-N11472
    Rhamnocitrin 3-glucoside

    Rhamnocitrin-3-O-β-D-glucopyranoside

    		 Others Others
    Rhamnocitrin 3-glucoside (Rhamnocitrin-3-O-β-D-glucopyranoside) is a natural product that can be isolated from Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (AM) .
    Rhamnocitrin 3-glucoside
  • HY-N1353R
    Rhamnocitrin (Standard)

    		Others p38 MAPK Cardiovascular Disease Inflammation/Immunology
    Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
    Rhamnocitrin (Standard)
  • HY-N10645
    Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside

    		Others Others
    Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside is a flavonol O-glycoside, isolated from Astragali semen of leguminous plants .
    Rhamnocitrin 3-O-β-D-apiofuranosyl(1→2)-β-D-glucopyranoside

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