Search Result

Results for "

Relative configuration

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Apoptosis (1) Biochemical Assay Reagents (1) Drug Isomer (1) EGFR (1) Estrogen Receptor/ERR (3) Fungal (1) GABA Receptor (1) Histone Methyltransferase (1) Isotope-Labeled Compounds (1) mAChR (1) mGluR (1) PARP (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (1) Prostaglandin Receptor (1) PROTACs (1) Raf (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) SGLT (1) Tyrosinase (2)
By Research Areas:	Cancer (5) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (4) Neurological Disease (1)

By Targets:

Androgen Receptor (1)

Apoptosis (1)

Biochemical Assay Reagents (1)

Drug Isomer (1)

EGFR (1)

Estrogen Receptor/ERR (3)

Fungal (1)

GABA Receptor (1)

Histone Methyltransferase (1)

Isotope-Labeled Compounds (1)

mAChR (1)

mGluR (1)

PARP (1)

Platelet-activating Factor Receptor (PAFR) (1)

Potassium Channel (1)

Prostaglandin Receptor (1)

PROTACs (1)

Raf (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (2)

SGLT (1)

Tyrosinase (2)

By Research Areas:

Cancer (5)

Endocrinology (1)

Infection (1)

Inflammation/Immunology (1)

Metabolic Disease (4)

Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W337569

(±)-Voriconazole (±)-UK-109496	Fungal	Others
(±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent .

HY-160440

rel-VU6021625	mAChR Drug Isomer	Others
rel-VU6021625 is the relative configuration of VU6021625 (HY-160440A). VU6021625 is a potent and selective mAChR M4 antagonist with IC₅₀ values of 0.44 nM and 57 nM for human M4, rat M4, respectively .

HY-18941B

(rel)-Eglumegad (rel)-LY354740; (rel)-Eglumetad	mGluR	Neurological Disease
(rel)-Eglumegad ((rel)-LY354740) is a relative configuration of Eglumegad (HY-18941). Eglumegad is a highly potent and selective group II (mGlu2/3) receptor agonist with EC₅₀s of 5 and 24 nM for transfected human mGlu2 and mGlu3 receptors, respectively .

HY-109092A

rel-Licogliflozin rel-LIK066	SGLT	Metabolic Disease Inflammation/Immunology
rel-Licogliflozin is a relative configuration of Licogliflozin (HY-109092). Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor .

HY-18957A

rel-Lifirafenib rel-BGB-283	Raf EGFR	Cancer
rel-Lifirafenib (rel-BGB-283) is the relative configuration of Lifirafenib (HY-18957). Lifirafenib is a potent Raf Kinase and EGFR inhibitor .

HY-N15739

(rel)-ent-Chromazonarol	Biochemical Assay Reagents	Others
(rel)-ent-Chromazonarol is the relative configuration of ent-Chromazonarol and is a sesquiterpene hydroquinone compound. (rel)-ent-Chromazonarol can be isolated from the sponge Disidea pallescens .

HY-Y1683R

DL-Menthol (Standard) Racementhol (Standard)	Reference Standards GABA Receptor	Others
DL-Menthol (Standard) is the analytical standard of DL-Menthol. This product is intended for research and analytical applications. DL-Menthol is a relative configuration of (-)-Menthol. DL-Menthol relates to the activation of GABAA receptor .

HY-13607A

(rel)-BMS-641988	Androgen Receptor	Cancer
(rel)-BMS-641988 is a relative configuration of BMS-641988. BMS-641988 is a potent nonsteroidal androgen receptor antagonist. BMS-641988 has the potential for the research of prostate cancer .

HY-117283

rel-Aprikalim rel-RP 52891	Potassium Channel	Others
rel-Aprikalim (rel-RP 52891) is the relative configuration of Aprikalim (HY-121183). Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K ⁺ (KATP) channels in guinea pig ventricular myocytes .

HY-103451A

rel-(R,R)-THC	Estrogen Receptor/ERR	Metabolic Disease
rel-(R,R)-THC is the relative configuration of (R,R)-THC (HY-103451). (R,R)-THC is an ERα agonist and an ERβ antagonist, with K_is of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6 .

HY-101512D

rel-A-395 hydrochloride	Histone Methyltransferase	Cancer
rel-A-395 hydrochloride is the relative configuration of A-395 (HY-101512) hydrochloride. A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC₅₀ of 18 nM .

HY-113068

(rel)-β-Tocopherol	Tyrosinase	Metabolic Disease
(rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol .

HY-100449A

(S)-AL-8810	Prostaglandin Receptor	Endocrinology
(S)-AL 8810 is an 11β-fluoro analog of PGF2α that acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the inverse, (S), or "natural" configuration at C-15 relative to AL 8810, which is 15-(R) .

HY-N12207

Neohelmanthicin C	Others	Others
Neohelmanthicin C is a phenylpropionic acid compound .

HY-128838A

(rel)-PROTAC ERRα Degrader-1 1 Publications Verification	Estrogen Receptor/ERR	Others
(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1. PROTAC ERRα Degrader-1 comprises a MDM2 ligand binding group, a linker and an estrogen-related receptor alpha (ERRa) binding group. PROTAC ERRα Degrader-1 is an estrogen-related receptor alpha (ERRa) degrader .

HY-90001S3

rel-Ritonavir-d6 rel-ABT 538-d₆; rel-RTV-d₆	Isotope-Labeled Compounds	Infection
rel-Ritonavir-d₆ (rel-ABT 538-d₆) is the deuterium labeled rel-Ritonavir. rel-Ritonavir is a relative configuration of Ritonavir (HY-90001). Ritonavir (ABT 538) is an inhibitor of HIV protease used to study of HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC₅₀ of 1.61 μM .

HY-106899A

(rel)-MK 287 (rel)-L-680573	Platelet-activating Factor Receptor (PAFR)	Others
(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287, a tetrahydrofuran analog, potently inhibited [ ³H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K_is of 6.1 nM, 3.2 nM and 5.49 nM, respectively. MK 287 inhibits PAF-induced lethality in mice and PAF-induced bronchoconstriction in guinea pigs .

HY-122359A

rel-Levormeloxifene rel-L-Centchroman; Ormeloxifene	Estrogen Receptor/ERR Apoptosis Reactive Oxygen Species (ROS)	Cancer
rel-Levormeloxifene (rel-L-Centchroman) is the relative configuration of Levormeloxifene (HY-122359). rel-Levormeloxifene is a selective estrogen receptor modulator (SERM). rel-Levormeloxifene inhibits proliferation of leukemia cells with IC₅₀ about 7 μM, arrests cell cycle at G0/G1 phase, and induces apoptosis. rel-Levormeloxifene induces differentation of myelogenesis leukemia, and enhances ROS production in K562 cells .

HY-114324A

rel-PROTAC PARP1 degrader	PROTACs PARP	Cancer
rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC₅₀ of 6.12 μM.

HY-113068R

(rel)-β-Tocopherol (Standard)	Reference Standards Tyrosinase	Metabolic Disease
(rel)-β-Tocopherol (Standard) is the analytical standard of (rel)-β-Tocopherol. This product is intended for research and analytical applications. (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol .

Cat. No.	Product Name	Category	Target	Chemical Structure